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SCNN1A Produits

(Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009].

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Catégories SCNN1A en vedette

SCNN1A Anticorps

High quality antibodies with extensive validation data.

SCNN1A Kits ELISA

Reliable ELISA kits for a wide range of species.

SCNN1A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SCNN1A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IF, IP, ICC
Validations
  • (19)
  • (5)
N° du produit ABIN863203
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IF, ICC
Validations
  • (19)
  • (5)
N° du produit ABIN863204
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IF, IP, ICC
Validations
  • (19)
  • (4)
N° du produit ABIN863202
Quantité 100 μg
Fiche technique Fiche technique

SCNN1A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959542
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959543
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Competition ELISA
Validations
N° du produit ABIN2112065
Quantité 96 tests
Fiche technique Fiche technique

SCNN1A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3122893
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3076645
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3122894
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits SCNN1A

Sudarikova, Bychkov, Kulbatskii, Chubinskiy-Nadezhdin, Shlepova, Shulepko, Koshelev, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer." dans: Frontiers in oncology, Vol. 12, pp. 904742, (2022) (PubMed).

Bychkov, Kirichenko, Shulepko, Mikhaylova, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." dans: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).

Khedr, Palygin, Pavlov, Blass, Levchenko, Alsheikh, Brands, El-Meanawy, Staruschenko: "Increased ENaC activity during kidney preservation in Wisconsin solution." dans: BMC nephrology, Vol. 20, Issue 1, pp. 145, (2020) (PubMed).

Scortegagna, Berthon, Settas, Giannakou, Garcia, Li, James, Liddington, Vilches-Moure, Stratakis, Ronai: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." dans: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).

Blass, Klemens, Brands, Palygin, Staruschenko: "Postprandial Effects on ENaC-Mediated Sodium Absorption." dans: Scientific reports, Vol. 9, Issue 1, pp. 4296, (2019) (PubMed).

Li, Chen, Yang, He, He, Xia, Zhang, Xiang: "Single-walled carbon nanohorn aggregates promotes mitochondrial dysfunction-induced apoptosis in hepatoblastoma cells by targeting SIRT3." dans: International journal of oncology, Vol. 53, Issue 3, pp. 1129-1137, (2018) (PubMed).

Liang, Wang, Yang, Niu, Hu, Zhang, Wu, Yu, Chen, Song, Zhang, Ma: "Oxidized low-density lipoprotein stimulates epithelial sodium channels in endothelial cells of mouse thoracic aorta." dans: British journal of pharmacology, Vol. 175, Issue 8, pp. 1318-1328, (2018) (PubMed).

Czikora, Alli, Sridhar, Matthay, Pillich, Hudel, Berisha, Gorshkov, Romero, Gonzales, Wu, Huo, Su, Verin, Fulton, Chakraborty, Eaton, Lucas: "Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction." dans: Frontiers in immunology, Vol. 8, pp. 842, (2017) (PubMed).

Pavlov, Levchenko, Ilatovskaya, Moreno, Staruschenko: "Renal sodium transport in renin-deficient Dahl salt-sensitive rats." dans: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 17, Issue 3, (2017) (PubMed).

Yamamoto, Hotta, Maeda, Kataoka, Maeda, Hamakawa, Sasaki, Yasui, Asai, Kimura: "Mineralocorticoid receptor stimulation induces urinary storage dysfunction via upregulation of epithelial sodium channel expression in the rat urinary bladder epithelium." dans: Journal of pharmacological sciences, Vol. 130, Issue 4, pp. 219-25, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à SCNN1A

sodium channel epithelial 1 alpha subunit (Scnn1a), sodium channel epithelial 1 alpha subunit (SCNN1A), sodium channel, nonvoltage-gated 1 alpha (Scnn1a), sodium channel, non voltage gated 1 alpha subunit L homeolog (scnn1a.L), alphaxENaC, BESC2, besc2, ENaC, ENAC, ENaCa, enaca, ENaCalpha, mENaC, SCNEA, SCNN1, Scnn1, scnn1, SCNN1A

Protein level used designations for SCNN1A

  • SCNEA
  • alpha-ENaC
  • alpha-NaCH
  • amiloride-sensitive sodium channel subunit alpha
  • epithelial Na(+) channel subunit alpha
  • epithelial sodium channel alpha subunit
  • nonvoltage-gated sodium channel 1 subunit alpha
  • sodium channel, nonvoltage-gated, type I, alpha
  • alpha ENaC-2
  • amiloride-sensitive epithelial sodium channel alpha subunit
  • amiloride-sensitive sodium channel subunit alpha 2
  • nasal epithelial sodium channel alpha subunit
  • sodium channel, nonvoltage-gated 1 alpha
  • ENaC alpha
  • amiloride-sensitive epithelial sodium channel
  • sodium channel, nonvoltage-gated, type I, alpha polypeptide
  • alpha ENaC
  • epithelial sodium channel ENaC alpha subunit
  • alpha cENaC 431
  • amiloride-sensitve epithelial sodium channel alpha subunit
  • alpha-subunit renal epithelial sodium channel
  • epithelium sodium channel alpha subunit
  • sodium channel, nonvoltage-gated 1, alpha
  • amiloride-sensitive sodium channel alpha subunit
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