SETD2 Produits
(SET Domain Containing 2 (SETD2))
Catégories
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008].
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Catégories SETD2 en vedette
SETD2 Anticorps
High quality antibodies with extensive validation data.
SETD2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (4)
- (10)
N° du produit
ABIN1682666
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (4)
N° du produit
ABIN7193416
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (1)
- (2)
N° du produit
ABIN238587
Quantité
100 μg
Fiche technique
Fiche technique
SETD2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6205033
Quantité
96 tests
Fiche technique
Fiche technique
SETD2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN2669625
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus
Validations
- (1)
N° du produit
ABIN2669663
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits SETD2
: "HnRNPL inhibits the osteogenic differentiation of PDLCs stimulated by SrCl2 through repressing Setd2." dans: Journal of cellular and molecular medicine, Vol. 23, Issue 4, pp. 2667-2677, (2020) (PubMed).: "H3K36me3-mediated mismatch repair preferentially protects actively transcribed genes from mutation." dans: The Journal of biological chemistry, Vol. 293, Issue 20, pp. 7811-7823, (2019) (PubMed).
: "Setd2 is associated with strontium-induced bone regeneration." dans: Acta biomaterialia, Vol. 53, pp. 495-505, (2018) (PubMed).
: "Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity." dans: Cell, Vol. 170, Issue 3, pp. 492-506.e14, (2017) (PubMed).
: "SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing." dans: Nucleic acids research, Vol. 45, Issue 1, pp. 92-105, (2017) (PubMed).
: "Histone methyltransferase Setd2 is critical for the proliferation and differentiation of myoblasts." dans: Biochimica et biophysica acta. Molecular cell research, Vol. 1864, Issue 4, pp. 697-707, (2017) (PubMed).
: "SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. ..." dans: Oncogene, Vol. 34, Issue 46, pp. 5699-708, (2015) (PubMed).
: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." dans: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, (2010) (PubMed).
: "Organization of chromatin and histone modifications at a transcription site." dans: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).
: "Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase." dans: The Journal of biological chemistry, Vol. 280, Issue 42, pp. 35261-71, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à SETD2
SET domain containing 2 (Setd2), SET domain containing 2 (SETD2), HBP231, HIF-1, HIP-1, HYPB, Kif9, KMT3A, p231HBP, SET2Protein level used designations for SETD2
- histone-lysine N-methyltransferase SETD2
- kinesin family member 9
- huntingtin interacting protein 1
- huntingtin yeast partner B
- huntingtin-interacting protein B
- lysine N-methyltransferase 3A
Avez-vous cherché autre chose?
- SETD1B
- SETD1A
- SETBP1
- SET7/9
- SET7
- SET/TAF-I
- SET Domain, Bifurcated 1
- SET Domain Containing (Lysine Methyltransferase) 8
- SET Binding Factor 2
- SET and MYND Domain Containing 2a
- SET and MYND Domain Containing 1
- Sestrin 2
- SESTD1
- SESN3
- SESN1
- Seryl-tRNA Synthetase
- serum/glucocorticoid Regulated Kinase 2
- serum/glucocorticoid Regulated Kinase 1
- Serum Amyloid A3 Pseudogene
- SERTM1
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