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SGCB Produits

(Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))

Catégories

This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008].

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Catégories SGCB en vedette

SGCB Anticorps

High quality antibodies with extensive validation data.

SGCB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

SGCB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (6)
N° du produit ABIN562847
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse, Rat
Application IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (4)
N° du produit ABIN738051
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
N° du produit ABIN7262903
Quantité 200 μL
Fiche technique Fiche technique

SGCB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Sandwich ELISA
Validations
N° du produit ABIN419867
Quantité 96 tests
Fiche technique Fiche technique

SGCB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124984
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319800
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1319798
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits SGCB

Brody, Vanhoutte, Schips, Boyer, Bakshi, Sargent, York, Molkentin: "Defective Flux of Thrombospondin-4 through the Secretory Pathway Impairs Cardiomyocyte Membrane Stability and Causes Cardiomyopathy." dans: Molecular and cellular biology, Vol. 38, Issue 14, (2018) (PubMed).

Siemionow, Cwykiel, Heydemann, Garcia, Marchese, Siemionow, Szilagyi: "Dystrophin Expressing Chimeric (DEC) Human Cells Provide a Potential Therapy for Duchenne Muscular Dystrophy." dans: Stem cell reviews, Vol. 14, Issue 3, pp. 370-384, (2018) (PubMed).

Pozsgai, Griffin, Heller, Mendell, Rodino-Klapac: "Systemic AAV-Mediated β-Sarcoglycan Delivery Targeting Cardiac and Skeletal Muscle Ameliorates Histological and Functional Deficits in LGMD2E Mice." dans: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 4, pp. 855-869, (2017) (PubMed).

Pozsgai, Griffin, Heller, Mendell, Rodino-Klapac: "β-Sarcoglycan gene transfer decreases fibrosis and restores force in LGMD2E mice." dans: Gene therapy, Vol. 23, Issue 1, pp. 57-66, (2016) (PubMed).

Vanhoutte, Schips, Kwong, Davis, Tjondrokoesoemo, Brody, Sargent, Kanisicak, Yi, Gao, Rabinowitz, Volk, McNally, Molkentin: "Thrombospondin expression in myofibers stabilizes muscle membranes." dans: eLife, Vol. 5, (2016) (PubMed).

Zhang, Cai, Chang, Yu, Wu, Yan, Zhai, Bi, Zhao, Xu, Tan, Qu, Lin: "Evidence of associations of APOBEC3B gene deletion with susceptibility to persistent HBV infection and hepatocellular carcinoma." dans: Human molecular genetics, Vol. 22, Issue 6, pp. 1262-9, (2013) (PubMed).

Esapa, Waite, Locke, Benson, Kraus, McIlhinney, Sillitoe, Beesley, Blake: "SGCE missense mutations that cause myoclonus-dystonia syndrome impair epsilon-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA." dans: Human molecular genetics, Vol. 16, Issue 3, pp. 327-42, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à SGCB

sarcoglycan beta (SGCB), sarcoglycan, beta (dystrophin-associated glycoprotein) (Sgcb), Sarcoglycan beta (Scgbeta), SarcoGlycaN (sgn-1), uncharacterized LOC5567384 (LOC5567384), beta-sarcoglycan (CpipJ_CPIJ006944), sarcoglycan, beta (Sgcb), sarcoglycan beta L homeolog (sgcb.L), sarcoglycan beta (Sgcb), sarcoglycan, beta (dystrophin-associated glycoprotein) (sgcb), 43kDa, A3b, AI747103, AI844814, beta-sarcoglycan, beta-SG, CG5657, Dmel\\CG5657, DmSCG-beta, dscgbeta, fa03a05, LGMD2E, scg-beta, SGC, wu:fa03a05, zgc:110833

Protein level used designations for SGCB

  • 43 kDa dystrophin-associated glycoprotein
  • 43DAG
  • beta-SG
  • beta-sarcoglycan
  • beta-sarcoglycan(43kD dystrophin-associated glycoprotein)
  • limb girdle muscular dystrophy 2E (non-linked families)
  • sarcoglycan, beta (43kD dystrophin-associated glycoprotein)
  • sarcoglycan beta
  • CG5657-PA
  • Scgbeta-PA
  • beta-sarcolgycan
  • SarcoGlycaN family member (sgn-1)
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