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anti-Human RHOC Anticorps:
anti-Rat (Rattus) RHOC Anticorps:
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Human Monoclonal RHOC Primary Antibody pour IF, ELISA - ABIN513476
Saito, Ohmasa, Shomori, Dimitriadis, Ohiwa, Shimizu, Tsounapi, Kinoshita, Satoh: Rhos and Rho kinases in the rat prostate: their possible functional roles and distributions. dans Molecular and cellular biochemistry 2011
Human Monoclonal RHOC Primary Antibody pour ELISA, WB - ABIN513475
Han, Li, Hu, Yu, Zheng, Guo, Zheng, Yi, Zhou: Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation. dans Endocrinology 2010
Human Polyclonal RHOC Primary Antibody pour IF (p), IHC (p) - ABIN687157
He, Wei, Du, Meng, Zheng, Lai, Yao, Zhou, Wang, Luo, Ma, Zhang: Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells. dans Cellular signalling 2017
Human Polyclonal RHOC Primary Antibody pour ELISA, WB - ABIN559936
Han, Yang, Li, Li, Zheng, Yu, Zhang, Zheng, Yi, Li, Guo, Zhou: RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia. dans Cell and tissue research 2016
Cow (Bovine) Polyclonal RHOC Primary Antibody pour IHC, WB - ABIN2786344
Sousa, Espreafico: Suppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets. dans BMC cancer 2008
Human Monoclonal RHOC Primary Antibody pour ELISA, WB - ABIN394719
Wu, Wu, Rosenthal, Rhee, Merajver: Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers. dans Cancer 2010
Show all 6 Pubmed References
a SDF-1 (Montrer CXCL12 Anticorps)/CXCR4 (Montrer CXCR4 Anticorps)-RhoA (Montrer RHOA Anticorps) and RhoC-ROS (Montrer ROS1 Anticorps)-cytoskeleton pathway that regulates Jurkat cell migration in response to SDF-1 (Montrer CXCL12 Anticorps).
Studied the involvement in epithelial ovarian cancer (EOC) of lncRNA ABHD11 (Montrer ABHD11 Anticorps)-AS1 (Montrer PTGDR Anticorps) in and the regulation of EOC by RhoC.
Out of multiple members of this family, RhoA (Montrer RHOA Anticorps) and RhoC are important factors. RhoA (Montrer RHOA Anticorps) is supposed to increase tumor proliferation when overexpressed while RhoC is responsible for tumor initiation.
Spatiotemporal analysis of RhoA (Montrer RHOA Anticorps)/RhoB/RhoC activation in primary human endothelial cells has been uncovered.
YMO1 (Montrer EPB41L5 Anticorps) suppresses tumor invasion and metastasis by inhibiting RhoC activity.
this studies show the ability of miR (Montrer MLXIP Anticorps)-10b to activate the expression of c-Jun (Montrer JUN Anticorps) through RhoC and NF1 (Montrer NF1 Anticorps), which represents a novel pathway for promoting migration and invasion of human cancer cells
swapping residue 188 identity effectively flips the membrane binding profile of wild-type RhoA (Montrer RHOA Anticorps) and RhoC through positive arginine contribution rather than negative phosphoserine regulation
HOTAIR is regulated by the RhoC-MRTF-A-SRF signaling pathway in breast cancer cells.
E2F transcription factor 1 (E2F1 (Montrer E2F1 Anticorps)) downregulated micrRNA miR (Montrer MLXIP Anticorps)-519d directly and miR (Montrer MLXIP Anticorps)-519d downregulated Ras homolog gene family member C (RhoC) directly.
These results reveal a previously unidentified pathway downstream of RHO that regulates the polarity of migrating cells through Golgi reorientation in a FAM65A-, CCM3 (Montrer PDCD10 Anticorps)- and MST3 (Montrer STK24 Anticorps)- and MST4 (Montrer MST4 Anticorps)-dependent manner.
what was seen for RhoC, mDia1 silencing through RNAi inhibited phagosome formation. Additionally, the coexpression of mDia1 with constitutively active mutant RhoC-G14V or expression of active mutant mDia1-DeltaN3 drastically inhibited the uptake of IgG-Es. These data suggest that RhoC modulates phagosome formation be modifying actin cytoskeletal remodeling via mDia1
RhoC co-localizes with Fam65b (Montrer FAM65B Anticorps) in stereocilia and regulates Fam65b (Montrer FAM65B Anticorps) oligomerization what is critical for hair cell function.
Inhibition of ovarian epithelial carcinoma tumorigenesis and progression by miR106b proceeds through the RhoC pathway.
RHOC and RAB38 (Montrer RAB38 Anticorps) are dispensable for osteoclast function.
A p27(kip1 (Montrer CDKN1B Anticorps))-binding protein, p27RF-Rho (Montrer LAMTOR1 Anticorps), promotes cancer metastasis via activation of RhoA (Montrer RHOA Anticorps) and RhoC.
We found that both RhoA and RhoC, but not RhoB, were required for initiation of centrosome duplication, and overactivation of RhoA, as well as RhoC, but not RhoB, promoted centrosome duplication and centrosome amplification.
RhoC has a role in metastasis of lung cancer in mice
loss of RhoC does not affect tumor development but decreases tumor cell motility and metastatic cell survival leading to a drastic inhibition of metastasis
RhoC promotes melanoma progression via separate mechanisms that regulate the PI3K/Akt (Montrer AKT1 Anticorps) pathway and the ROCK signaling pathway.
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
ras homolog gene family, member C
, rho-related GTP-binding protein RhoC
, RAS-related homolog 9
, oncogene RHO H9
, rho cDNA clone 9
, rhoC GTPase
, small GTP binding protein RhoC
, aplysia ras-related homolog 9 (RhoC)
, ras homolog 9 (RhoC)
, silica-induced gene 61 protein
, GTP-binding protein
, GTPase cRhoC