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SRPK2 Protéines

(SFRS Protein Kinase 2 (SRPK2))

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up- regulation. Plays an essential role in splicesomal B complex formation via the phosphorylation of DDX23/PRP28.

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SRPK2 Protein (AA 1-681) (His tag)

custom-made SRPK2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Srpk2 Protein, UniprotID O54781

3 images

N° du produit ABIN7562408

Détails

SRPK2 Protein (AA 1-688) (His tag)

custom-made SRPK2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant SRPK2 Protein, UniprotID P78362

3 images

N° du produit ABIN7555628

Détails

SRPK2 Protein (AA 1-699) (GST tag)

SRPK2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for SFRS Protein Kinase 2 (SRPK2) (AA 1-699) protein (GST tag) (ABIN1321350)

1 image

N° du produit ABIN1321350

Détails

SRPK2 Protein (AA 1-688) (GST tag)

SRPK2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for SFRS Protein Kinase 2 (SRPK2) (AA 1-688) protein (GST tag) (ABIN1321348)

1 image

N° du produit ABIN1321348

Détails

SRPK2 Protein (AA 1-689) (GST tag)

SRPK2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for SFRS Protein Kinase 2 (SRPK2) (AA 1-689) protein (GST tag) (ABIN1321346)

1 image

N° du produit ABIN1321346

Détails

SRPK2 Protein (AA 1-688) (GST-pstS1)

SRPK2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA

Image no. 1 for SFRS Protein Kinase 2 (SRPK2) (AA 1-688) protein (GST-pstS1) (ABIN1321352)

1 image

N° du produit ABIN1321352

Détails

SRPK2 Protein (GST tag)

SRPK2 Origine: Humain Hôte: Cellules d'insectes Recombinant 70 % - 90 % Func Active

N° du produit ABIN5509157

Détails

SRPK2 Protein (AA 380-617) (His tag)

SRPK2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC

N° du produit ABIN7416547

Détails

SRPK2 Protein (AA 1-681) (Strep Tag)

custom-made SRPK2 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, ELISA, SDS

N° du produit ABIN3131748

Détails

SRPK2 Protein (AA 1-688) (Strep Tag)

custom-made SRPK2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, ELISA, SDS

N° du produit ABIN3095669