UBA3 Protein (AA 1-463) (His tag)

N° du produit ABIN667686

Détail du produit

Antigène: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-463

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette UBA3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: UBA3, 1-463aa, Human, His tag, E.coli

Pureté: > 90 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Autre désignation: UBA3 (UBA3 Produits)

Synonymes: UBE1C Protein, hUBA3 Protein, Ube1c Protein, ube1c Protein, wu:fb75e04 Protein, wu:fc37b11 Protein, zgc:55528 Protein, A830034N06Rik Protein, AI256736 Protein, AI848246 Protein, AW546539 Protein, ubiquitin like modifier activating enzyme 3 Protein, ubiquitin-like modifier activating enzyme 3 Protein, ubiquitin like modifier activating enzyme 3 S homeolog Protein, UBA3 Protein, Uba3 Protein, uba3 Protein, uba3.S Protein

Sujet: UBA3, also known as NEDD8-activating enzyme E1 catalytic subunit, is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Recombinant human UBA3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: UBE1C. NCBI no.: AAH22853

Poids moléculaire: 54.4 kDa (487aa)