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WNT3 Produits

(Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Catégories

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008].

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Catégories WNT3 en vedette

WNT3 Anticorps

High quality antibodies with extensive validation data.

WNT3 Kits ELISA

Reliable ELISA kits for a wide range of species.

WNT3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

WNT3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (8)
N° du produit ABIN1490901
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
  • (4)
N° du produit ABIN185634
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN1490900
Quantité 100 μL
Fiche technique Fiche technique

WNT3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975653
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960541
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960542
Quantité 96 tests
Fiche technique Fiche technique

WNT3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1325359
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3075575
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409761
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits WNT3

Freis, Keller, Ludwig, Meese, Jauckus, Rehnitz, Capp, Strowitzki, Germeyer: "Altered miRNA-profile dependent on ART outcome in early pregnancy targets Wnt-pathway." dans: Reproduction (Cambridge, England), Vol. 154, Issue 6, pp. 799-805, (2018) (PubMed).

Kraushar, Viljetic, Wijeratne, Thompson, Jiao, Pike, Medvedeva, Groszer, Kiledjian, Hart, Rasin: "Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 31, pp. 10911-26, (2015) (PubMed).

Kuma, Yamada, Wang, Kitamura, Yamaguchi, Iwai, Izumi, Tamura, Otsuji, Kohno: "Role of WNT10A-expressing kidney fibroblasts in acute interstitial nephritis." dans: PLoS ONE, Vol. 9, Issue 7, pp. e103240, (2014) (PubMed).

Fujimaki, Hidaka, Asashima, Takemasa, Kuwabara: "Wnt protein-mediated satellite cell conversion in adult and aged mice following voluntary wheel running." dans: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7399-412, (2014) (PubMed).

Mattes, Weber, Peres, Chen, Davidson, Houart, Scholpp: "Wnt3 and Wnt3a are required for induction of the mid-diencephalic organizer in the caudal forebrain." dans: Neural development, Vol. 7, pp. 12, (2012) (PubMed).

Wu, Ginther, Kim, Mosher, Chung, Slamon, Vadgama: "Expression of Wnt3 activates Wnt/?-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells." dans: Molecular cancer research : MCR, Vol. 10, Issue 12, pp. 1597-606, (2012) (PubMed).

Okamoto, Inoue, Iwamura, Terashima, Soya, Asashima, Kuwabara: "Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 10, pp. 3570-82, (2011) (PubMed).

Schmitt, Shi, Wolf, Lu, King, Zou: "Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping." dans: Nature, Vol. 439, Issue 7072, pp. 31-7, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à WNT3

Wnt family member 3 (WNT3), Wnt family member 3 (Wnt3), wingless-type MMTV integration site family, member 3 (wnt3), proto-oncogene Wnt-3 (LOC468297), wingless-type MMTV integration site family member 3 (WNT3), Wnt family member 3A (WNT3A), Wnt family member 3 (wnt3), wingless-type MMTV integration site family, member 3 (Wnt3), wingless-type MMTV integration site family member 3 L homeolog (wnt3.L), Ci-Wnt3, Int-4, INT4, int4, wnt-3, Wnt-3, WNT3, wnt3, wnt3-A, wnt3l, Xwnt-3, Xwnt3

Protein level used designations for WNT3

  • WNT-3 proto-oncogene protein
  • proto-oncogene Int-4 homolog
  • proto-oncogene Wnt-3
  • Wingless-type MMTV integration site 3, homolog
  • wingless-related MMTV integration site 3
  • wingless-type MMTV integration site family member 3
  • wingless-type MMTV integration site family, member 3
  • wingless-related MMTV integration site 3A
  • proto-oncogene Wnt-3-like
  • proto-oncogene Int-4
  • proto-oncogene protein Wnt-3
  • Xwnt-3 region near C-terminus
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