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WISP2 Produits

(WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

Catégories

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008].

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Catégories WISP2 en vedette

WISP2 Anticorps

High quality antibodies with extensive validation data.

WISP2 Kits ELISA

Reliable ELISA kits for a wide range of species.

WISP2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

WISP2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN390188
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IP
Validations
  • (1)
  • (2)
N° du produit ABIN948739
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (3)
N° du produit ABIN563830
Quantité 100 μg
Fiche technique Fiche technique

WISP2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971204
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6973573
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960561
Quantité 96 tests
Fiche technique Fiche technique

WISP2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325343
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3075541
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7508309
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits WISP2

Ji, Jia, Jia, Ji, Hargest, Jiang: "WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-? pathways." dans: British journal of cancer, Vol. 113, Issue 6, pp. 921-33, (2015) (PubMed).

Conde, Scotece, Abella, Gómez, López, Villar, Hermida, Pino, Gómez-Reino, Gualillo: "Identification of novel adipokines in the joint. Differential expression in healthy and osteoarthritis tissues." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0123601, (2015) (PubMed).

Huang, Caputo, Noordmans, Yazdani, Monteiro, van den Born, van Goor, Heeringa, Korstanje, Hillebrands: "Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice." dans: PloS one, Vol. 9, Issue 3, pp. e91850, (2015) (PubMed).

Banerjee, Saxena, Sengupta, Tawfik, Mayo, Banerjee: "WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation." dans: Neoplasia (New York, N.Y.), Vol. 5, Issue 1, pp. 63-73, (2003) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." dans: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à WISP2

WNT1 inducible signaling pathway protein 2 (WISP2), WNT1 inducible signaling pathway protein 2 S homeolog (wisp2.S), WNT1 inducible signaling pathway protein 2 (wisp2), WNT1 inducible signaling pathway protein 2 (Wisp2), ccn5, CCN5, Ccn5, Crgr4, CT58, CTGF-L, Ctgfl, MGC84196, Rcop1, WISP2

Protein level used designations for WISP2

  • WNT1 inducible signaling pathway protein 2
  • Wnt-1 inducible-signaling pathway protein 2
  • WNT1 inducible signaling pathway 2
  • zWISP2-c23
  • CCN family member 5
  • WISP-2
  • WNT1-inducible-signaling pathway protein 2
  • connective tissue growth factor-like protein
  • connective tissue growth factor-related protein 58
  • wnt-1 signaling pathway protein 2
  • CTGF-L
  • CCN family protein COP-1
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