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WNK1 Produits

(WNK Lysine Deficient Protein Kinase 1 (WNK1))
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010].

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Catégories WNK1 en vedette

WNK1 Anticorps

High quality antibodies with extensive validation data.

WNK1 Kits ELISA

Reliable ELISA kits for a wide range of species.

WNK1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

WNK1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6256585
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7169222
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6266031
Quantité 100 μL
Fiche technique Fiche technique

WNK1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380142
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN2747913
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN2747914
Quantité 96 tests
Fiche technique Fiche technique

WNK1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5569680
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325348
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307180
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits WNK1

Wade, Fang, Liu, Li, Yang, Subramanya, Maouyo, Mason, Ellison, Welling: "WNK1 kinase isoform switch regulates renal potassium excretion." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 22, pp. 8558-63, (2006) (PubMed).

Anselmo, Earnest, Chen, Juang, Kim, Zhao, Cobb: "WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 29, pp. 10883-8, (2006) (PubMed).

Xu, Lee, Min, Lenertz, Heise, Stippec, Goldsmith, Cobb: "WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension." dans: Cell research, Vol. 15, Issue 1, pp. 6-10, (2005) (PubMed).

Nuaray-Fejes-Tuoth, Snyder, Fejes-Tuoth: "The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 50, pp. 17434-9, (2004) (PubMed).

Xu, Min, Stippec, Lee, Goldsmith, Cobb: "Regulation of WNK1 by an autoinhibitory domain and autophosphorylation." dans: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48456-62, (2002) (PubMed).

Omasa, Chen, Mantalaris, Tsai, Wu: "Molecular cloning and sequencing of the human heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase from bone marrow culture." dans: DNA sequence : the journal of DNA sequencing and mapping, Vol. 13, Issue 3, pp. 133-7, (2002) (PubMed).

Veríssimo, Jordan: "WNK kinases, a novel protein kinase subfamily in multi-cellular organisms." dans: Oncogene, Vol. 20, Issue 39, pp. 5562-9, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à WNK1

WNK lysine deficient protein kinase 1 (WNK1), WNK lysine deficient protein kinase 1 L homeolog (wnk1.L), WNK lysine deficient protein kinase 1 (wnk1), serine/threonine-protein kinase WNK1 (LOC100056745), WNK lysine deficient protein kinase 1 (Wnk1), with no lysine (K) kinase 1 (WNK1), 6430573H23Rik, ATWNK1, EG406236, HSAN2, hsan2, HSN2, hsn2, Hsn2, KDP, kdp, mKIAA0344, p65, pha2c, PRKWNK1, prkwnk1, Prkwnk1, PSK, psk, T9J14.14, T9J14_14, with no lysine (K) kinase 1, WNK1, ZIK4

Protein level used designations for WNK1

  • WNK lysine deficient protein kinase 1 isoform
  • erythrocyte 65 kDa protein
  • prostate-derived sterile 20-like kinase
  • protein kinase with no lysine 1
  • serine/threonine-protein kinase WNK1
  • WNK lysine deficient protein kinase 1
  • serine/threonine-protein kinase WNK1-like
  • protein kinase lysine-deficient 1
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