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WNK4 Produits

(WNK Lysine Deficient Protein Kinase 4 (WNK4))
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009].

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Catégories WNK4 en vedette

WNK4 Anticorps

High quality antibodies with extensive validation data.

WNK4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

WNK4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7169234
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (2)
N° du produit ABIN528800
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (2)
  • (1)
N° du produit ABIN540240
Quantité 100 μL
Fiche technique Fiche technique

WNK4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5569662
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325354
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3096394
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits WNK4

Huguet, Le Dudal, Livrozet, Bazin, Frochot, Perez, Haymann, Brocheriou, Daudon, Letavernier: "High frequency and wide range of human kidney papillary crystalline plugs." dans: Urolithiasis, (2018) (PubMed).

Kim, Yang, Kim, Kang, Kim, Cho: "Role of nitric oxide and WNK-SPAK/OSR1-KCC2 signaling in daily changes in GABAergic inhibition in the rat dorsal raphe neurons." dans: Neuropharmacology, Vol. 135, pp. 355-367, (2018) (PubMed).

Bhuiyan, Song, Yuan, Begum, Kofler, Kahle, Yang, Lin, Alper, Subramanya, Sun: "WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 37, Issue 8, pp. 2780-2794, (2017) (PubMed).

Li, Hatano, Xu, Wan, Yang, Weinstein, Palmer, Wang: "Gender difference in kidney electrolyte transport. I. Role of AT1a receptor in thiazide-sensitive Na+-Cl- cotransporter activity and expression in male and female mice." dans: American journal of physiology. Renal physiology, Vol. 313, Issue 2, pp. F505-F513, (2017) (PubMed).

Andrukhova, Smorodchenko, Egerbacher, Streicher, Zeitz, Goetz, Shalhoub, Mohammadi, Pohl, Lanske, Erben: "FGF23 promotes renal calcium reabsorption through the TRPV5 channel." dans: The EMBO journal, Vol. 33, Issue 3, pp. 229-46, (2014) (PubMed).

Ohno, Uchida, Ohashi, Nitta, Ohta, Chiga, Sasaki, Uchida: "Immunolocalization of WNK4 in mouse kidney." dans: Histochemistry and cell biology, Vol. 136, Issue 1, pp. 25-35, (2011) (PubMed).

Uchida: "Pathophysiological roles of WNK kinases in the kidney." dans: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 4, pp. 695-702, (2010) (PubMed).

Subramanya, Liu, Ellison, Wade, Welling: "WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction." dans: The Journal of biological chemistry, Vol. 284, Issue 27, pp. 18471-80, (2009) (PubMed).

Song, Hu, Riazi, Tiwari, Wade, Ecelbarger: "Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats." dans: American journal of physiology. Renal physiology, Vol. 290, Issue 5, pp. F1055-64, (2006) (PubMed).

Kahle, Gimenez, Hassan, Wilson, Wong, Forbush, Aronson, Lifton: "WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 2064-9, (2004) (PubMed).

Synonymes et noms alternatifs relatifs à WNK4

WNK lysine deficient protein kinase 4 (WNK4), WNK lysine deficient protein kinase 4 (Wnk4), 2010002J11Rik, Ac2-059, PHA2B, Pha2b, PRKWNK4, Prkwnk4, WNK4

Protein level used designations for WNK4

  • WNK lysine deficient protein kinase 4
  • protein kinase lysine-deficient 4
  • protein kinase with no lysine 4
  • serine/threonine-protein kinase WNK4
  • protein kinase, lysine deficient 4
  • WNK4 Ser/Thr kinase
  • protein kinase, lysine-deficient 4
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