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XPO1 Produits

(Exportin 1 (XPO1))

Catégories

The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jul 2008].

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Catégories XPO1 en vedette

XPO1 Anticorps

High quality antibodies with extensive validation data.

XPO1 Kits ELISA

Reliable ELISA kits for a wide range of species.

XPO1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

XPO1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN7267067
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC
Validations
  • (7)
N° du produit ABIN4886771
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7152317
Quantité 100 μg
Fiche technique Fiche technique

XPO1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955675
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1132696
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1132695
Quantité 96 tests
Fiche technique Fiche technique

XPO1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1325446
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3096383
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7413031
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits XPO1

Kalita, Kapinos, Zheng, Rencurel, Zilman, Lim: "Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage." dans: The Journal of cell biology, Vol. 221, Issue 3, (2022) (PubMed).

Seervi, Sumi, Chandrasekharan, Sharma, SanthoshKumar: "Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway." dans: Cellular oncology (Dordrecht), Vol. 42, Issue 5, pp. 645-661, (2020) (PubMed).

Steyaert, Scheveneels, Vanneste, Van Damme, Robberecht, Callaerts, Bogaert, Van Den Bosch: "FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins." dans: Human molecular genetics, Vol. 27, Issue 23, pp. 4103-4116, (2019) (PubMed).

García-Aguirre, Alamillo-Iniesta, Rodríguez-Pérez, Vélez-Aguilera, Amaro-Encarnación, Jiménez-Gutiérrez, Vásquez-Limeta, Samuel Laredo-Cisneros, Morales-Lázaro, Tiburcio-Félix, Ortega, Magaña, Winder et al.: "Enhanced nuclear protein export in premature aging and rescue of the progeria phenotype by modulation of CRM1 activity. ..." dans: Aging cell, Vol. 18, Issue 5, pp. e13002, (2019) (PubMed).

Vélez-Aguilera, de Dios Gómez-López, Jiménez-Gutiérrez, Vásquez-Limeta, Laredo-Cisneros, Gómez, Winder, Cisneros: "Control of nuclear β-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function." dans: Biochimica et biophysica acta. Molecular cell research, Vol. 1865, Issue 2, pp. 406-420, (2018) (PubMed).

Seipel, Marques, Bozzini, Meinken, Mueller, Pabst: "Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid Leukemia." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 3, pp. 746-56, (2016) (PubMed).

Oka, Mura, Yamada, Sangel, Hirata, Maehara, Kawakami, Tachibana, Ohkawa, Kimura, Yoneda: "Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes." dans: eLife, Vol. 5, pp. e09540, (2016) (PubMed).

Vercruysse, De Bie, Neggers, Jacquemyn, Vanstreels, Schmid-Burgk, Hornung, Baloglu, Landesman, Senapedis, Shacham, Dagklis, Cools, Daelemans: "The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, (2016) (PubMed).

Bagheri, Badduke, Qiao, Colnaghi, Abramowicz, Alcantara, Dunham, Wen, Wildin, Nowaczyk, Eichmeyer, Lehman, Maranda, Martell, Shan, Lewis, ODriscoll, Gregory-Evans, Rajcan-Separovic: "Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis." dans: JCI insight, Vol. 1, Issue 3, pp. e85461, (2016) (PubMed).

Sharma, Åkerström, Sharma, Chow, Teow, Abrenica, Booth, Booth, Mirazimi, Lal: "SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus." dans: PLoS ONE, Vol. 6, Issue 5, pp. e19436, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à XPO1

embargoed (emb), exportin 1 (cgd3_3060), exportin 1 (Tc00.1047053511725.150), exportin 1 (Tb11.01.5940), exportin 1 (BBOV_II007220), putative exportin 1 (LMJF_32_1100), chromosome region maintenance protein 1 (xpo1), exportin 1 (Xpo1), exportin 1 (XPO1), exportin-1 (LOC100165622), exportin 1 (CRM1 homolog, yeast) (XPO1), exportin-1 (LOC100633509), exportin 1 S homeolog (xpo1.S), 18.m06600, AA420417, CG13387, CRM1, Crm1, crm1, DCRM1, dCRM1, DDBDRAFT_0183812, DDBDRAFT_0234066, DDB_0183812, DDB_0234066, Dmel\\CG13387, Emb, emb, exp1, Exp1, exportin-1, l(2)k16715, LOC100220104, Xpo, XPO-1, XPO1, Xpo1

Protein level used designations for XPO1

  • CG13387-PA
  • Exportin-1
  • chromosomal region maintenance 1
  • emb-PA
  • exportin
  • exportin 1
  • exportin-1
  • exportin 1 (CRM1 homolog, yeast)
  • exportin 1-like
  • exportin-1-like
  • CRM1, yeast, homolog
  • chromosome region maintenance 1 protein homolog
  • exportin 1 (CRM1, yeast, homolog)
  • exportin-1 (required for chromosome region maintenance)
  • nuclear export factor CRM1
  • CRM1/XPO1 protein
  • exp1
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