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XPA Produits

(Xeroderma Pigmentosum, Complementation Group A (XPA))

Catégories

This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009].

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Catégories XPA en vedette

XPA Anticorps

High quality antibodies with extensive validation data.

XPA Kits ELISA

Reliable ELISA kits for a wide range of species.

XPA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

XPA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC (p), IP, ICC
Validations
  • (1)
  • (4)
N° du produit ABIN2855566
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
N° du produit ABIN948624
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN652730
Quantité 400 μL
Fiche technique Fiche technique

XPA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381596
Quantité 96 tests
Fiche technique Fiche technique

XPA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325438
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3075637
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7422931
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits XPA

Manandhar, Lowery, Boulware, Lin, Lu, Wood: "Transcriptional consequences of XPA disruption in human cell lines." dans: DNA repair, Vol. 57, pp. 76-90, (2017) (PubMed).

Saquilabon Cruz, Kong, Silva, Khatibzadeh, Thai, Berns, Yokomori: "Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites." dans: Nucleic acids research, Vol. 44, Issue 3, pp. e27, (2016) (PubMed).

ODowd, Zavala, Brown, Mori, Fortunato: "HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome." dans: PLoS pathogens, Vol. 8, Issue 11, pp. e1003038, (2012) (PubMed).

Saijo, Matsuda, Kuraoka, Tanaka: "Inhibition of nucleotide excision repair by anti-XPA monoclonal antibodies which interfere with binding to RPA, ERCC1, and TFIIH." dans: Biochemical and biophysical research communications, Vol. 321, Issue 4, pp. 815-22, (2004) (PubMed).

Araújo, Nigg, Wood: "Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome." dans: Molecular and cellular biology, Vol. 21, Issue 7, pp. 2281-91, (2001) (PubMed).

Evans, Fellows, Coffer, Wood: "Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein." dans: The EMBO journal, Vol. 16, Issue 3, pp. 625-38, (1997) (PubMed).

Aboussekhra, Biggerstaff, Shivji, Vilpo, Moncollin, Podust, Protić, Hübscher, Egly, Wood: "Mammalian DNA nucleotide excision repair reconstituted with purified protein components." dans: Cell, Vol. 80, Issue 6, pp. 859-68, (1995) (PubMed).

Tanaka, Miura, Satokata, Miyamoto, Yoshida, Satoh, Kondo, Yasui, Okayama, Okada: "Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain." dans: Nature, Vol. 348, Issue 6296, pp. 73-6, (1990) (PubMed).

Synonymes et noms alternatifs relatifs à XPA

Xeroderma pigmentosum group A-like (Xpac), XPA, DNA damage recognition and repair factor (XPA), xeroderma pigmentosum, complementation group A (Xpa), XPA, DNA damage recognition and repair factor (Xpa), xeroderma pigmentosum, complementation group A L homeolog (xpa.L), AI573865, CG6358, DhR14, DhXPA, Dmel\\CG6358, DmXPA, dmXPA, Dxpa, dxpa, EG:EG0007.8, XP1, Xpa, XPAC, Xpac, xpac, XPA_DROME, xxpa

Protein level used designations for XPA

  • CG6358-PA
  • Xpac-PA
  • xeroderma pigmentosum group A-like
  • DNA repair protein complementing XP-A cells
  • excision repair-controlling
  • xeroderma pigmentosum group A-complementing protein
  • DNA repair protein complementing XP-A cells homolog
  • xeroderma pigmentosum group A-complementing protein homolog
  • xpacch protein
  • xpacx1 protein
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