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CD14 anticorps

Il existe 4+ publications pour ce produit. L’anticorps anti-CD14 Monoclonal Souris est utilisé pour la détection de CD14 dans des échantillons de Humain. Il a été validé pour FACS, ELISA et IHC (p).
Pubmed (4 références)
N° du produit ABIN93977
279,31 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 2 à 4 jours ouvrables

Aperçu rapide pour CD14 anticorps (ABIN93977)

Antigène

Voir toutes CD14 Anticorps
CD14

Reactivité

  • 367
  • 61
  • 39
  • 26
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Humain

Hôte

  • 291
  • 89
  • 35
  • 14
  • 3
  • 1
  • 1
  • 1
Souris

Clonalité

  • 363
  • 68
  • 3
Monoclonal

Conjugué

  • 194
  • 39
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Cet anticorp CD14 est non-conjugé

Application

  • 274
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Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

B-A8
Discover our top product CD14 Anticorps primaire

  • Fonction

    Anti-Hu CD14 Purified

    Réactivité croisée (Details)

    Human

    Attributs du produit

    The mouse monoclonal antibody B-A8 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked extracellular membrane glycoprotein expressed on the surface of monocytes, macrophages and weakly on granulocytes, also expressed by most tissue macrophages.

    Purification

    Purified by protein-A affinity chromatography.

    Pureté

    > 95 % (by SDS-PAGE)

    Immunogène

    Human monocytes

    Isotype

    IgG1
  • anti-CD14 (CD14) (AA 54-83), (N-Term) antibody
    anti-CD14 (CD14) (AA 54-83), (N-Term) antibody

    CD14 Reactivité: Humain FACS, WB, IF, IHC (p) Hôte: Lapin Polyclonal RB14105 unconjugated

    anti-CD14 (CD14) (AA 20-214) antibody
    anti-CD14 (CD14) (AA 20-214) antibody

    CD14 Reactivité: Humain, Souris FACS, WB, IHC, ELISA Hôte: Souris Monoclonal 4B4F12 unconjugated

    anti-CD14 (CD14) (AA 20-214) antibody
    anti-CD14 (CD14) (AA 20-214) antibody

    CD14 Reactivité: Humain IHC, ELISA, ICC Hôte: Souris Monoclonal 1H5D8 unconjugated

    anti-CD14 (CD14) (AA 25-148) antibody
    anti-CD14 (CD14) (AA 25-148) antibody

    CD14 Reactivité: Humain FACS, WB, IHC Hôte: Souris Monoclonal LPSR-2385 unconjugated

    anti-CD14 (CD14) antibody
    anti-CD14 (CD14) antibody

    CD14 Reactivité: Humain IHC, ELISA Hôte: Souris Monoclonal 1A3B6 unconjugated

    anti-CD14 (CD14) (AA 20-345) antibody
    anti-CD14 (CD14) (AA 20-345) antibody

    CD14 Reactivité: Humain FACS, WB, IHC, IF, ELISA Hôte: Souris Monoclonal 14G1F3 unconjugated

    anti-CD14 (CD14) (AA 230-345) antibody
    anti-CD14 (CD14) (AA 230-345) antibody

    CD14 Reactivité: Humain FACS, WB, IHC, ELISA Hôte: Souris Monoclonal 1D1F8 unconjugated

    anti-CD14 (CD14) (AA 65-327) antibody
    anti-CD14 (CD14) (AA 65-327) antibody

    CD14 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated

    anti-CD14 (CD14) (Internal Region) antibody
    anti-CD14 (CD14) (Internal Region) antibody

    Verified CD14 Reactivité: Humain FACS, WB, ELISA Hôte: Chèvre Polyclonal unconjugated

    anti-CD14 (CD14) (AA 25-148) antibody
    anti-CD14 (CD14) (AA 25-148) antibody

    CD14 Reactivité: Humain WB, IHC Hôte: Souris Monoclonal LPSR-2397 unconjugated

  • Indications d'application

    ELISA: The antibody B-A8 has been tested as the capture antibody in a sandwich ELISA for analysis of human CD14 in combination with antibody MEM-18 (cat. no. 1B-212-C100). Flow cytometry: recommended dilution: 1 μg/mL, Immunohistochemistry (paraffin sections): recommended dilution: 2-10 μg/mL, positive tissue: PML brain sections, positive staining on human PML brain sections was mainly observed on monocytes in the lumenal side of brain blood vessels, and on some perivascular cells adjacent to medium-sized vessels. Heat retrieval of antigen is recommeded.

    Restrictions

    For Research Use only

  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Do not freeze

    Stock

    4 °C

    Stockage commentaire

    Store at 2-8°C. Do not freeze.
  • Yates, Rovis, Mitchell, Afzali, Tsang, Garin, Lechler, Lombardi, Garden: "The maintenance of human CD4+ CD25+ regulatory T cell function: IL-2, IL-4, IL-7 and IL-15 preserve optimal suppressive potency in vitro." dans: International immunology, Vol. 19, Issue 6, pp. 785-99, (2007) (PubMed).

    Kuusniemi, Lapatto, Holmberg, Karikoski, Rapola, Jalanko: "Kidneys with heavy proteinuria show fibrosis, inflammation, and oxidative stress, but no tubular phenotypic change." dans: Kidney international, Vol. 68, Issue 1, pp. 121-32, (2005) (PubMed).

    Matasić, Dietz, Vuk-Pavlović: "Dexamethasone inhibits dendritic cell maturation by redirecting differentiation of a subset of cells." dans: Journal of leukocyte biology, Vol. 66, Issue 6, pp. 909-14, (2000) (PubMed).

    Goyert, Ferrero, Rettig, Yenamandra, Obata, Le Beau: "The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors." dans: Science (New York, N.Y.), Vol. 239, Issue 4839, pp. 497-500, (1988) (PubMed).

  • Antigène

    CD14

    Autre désignation

    CD14

    Sujet

    CD14 Molecule,CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where it serves as a multifunctional lipopolysaccharide receptor. It is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.,LPS-receptor, LPSR, MCLR

    ID gène

    929

    UniProt

    P08571

    Pathways

    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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