HIF1A anticorps
Aperçu rapide pour HIF1A anticorps (ABIN659179)
Antigène
Voir toutes HIF1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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Immunogène
- This HIF1A monoclonal antibody is generated from mouse immunized with HIF1A recombinant protein.
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Isotype
- IgM kappa
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Indications d'application
- WB: 1:100~1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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: "20(s)-Protopanaxadiol (PPD) increases the radiotherapy sensitivity of laryngeal carcinoma." dans: Food & function, Vol. 8, Issue 12, pp. 4469-4477, (2018) (PubMed).
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- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
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Autre désignation
- HIF1A
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Sujet
- Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.
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Poids moléculaire
- 92670
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NCBI Accession
- NP_001230013, NP_001521, NP_851397
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UniProt
- Q16665
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, L'effet Warburg
Antigène
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