HIF1A anticorps (AA 432-528)
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- Antigène Voir toutes HIF1A Anticorps
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
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Épitope
- AA 432-528
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Porc, Singe, Mouton, Furet
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp HIF1A est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Chromatin Immunoprecipitation (ChIP), Gel Shift (GS)
- Specificité
- Reacts with human HIF-1 alpha
- Réactivité croisée
- Souris, Boeuf (Vache), Lapin, Mouton
- Réactivité croisée (Details)
- Cross reacts with proteins from monkey, sheep, mouse, rat, rabbit, pig, bovine and ferret.
- Purification
- Purified (protein A)
- Immunogène
- Fusion protein containing amino acids 432-528 of human HIF-1alpha
- Clone
- H1alpha67
- Isotype
- IgG2b
- Top Product
- Discover our top product HIF1A Anticorps primaire
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- Indications d'application
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC1:100-1:300 WB1:500-1:1000 ICC/ IF1:100-1:500 IP1:10 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.5 mg/mL
- Buffer
- Tris-glycine, 150 mM NaCl pH 7.5, Sodium azide 0.05 %
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 4°C. Do not freeze.
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- Antigène
- HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
- Autre désignation
- Hypoxia-Inducible Factor 1-alpha (HIF1A Produits)
- Synonymes
- anticorps hif1a, anticorps AA959795, anticorps HIF1alpha, anticorps MOP1, anticorps bHLHe78, anticorps HIF-1A, anticorps HIF-1alpha, anticorps HIF1, anticorps HIF1-ALPHA, anticorps PASD8, anticorps HIF1-alpha, anticorps hif-1a, anticorps hypoxia inducible factor 1 alpha, anticorps hypoxia inducible factor 1, alpha subunit, anticorps hypoxia inducible factor 1 alpha subunit, anticorps HIF (Hypoxia Inducible Factor) homologa, anticorps hif-1a, anticorps Hif1a, anticorps HIF1A, anticorps hif1a, anticorps hif-1
- Sujet
- HIF-1 is a nuclear protein involved in mammalian oxygen homeostasis. This occurs as a posttranslational modification by prolyl hydroxylation. HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits. Both subunits are constantly translated. However, under normoxic conditions, human HIF-1 alpha is hydroxylated at Pro402 or Pro564 by a set of HIF prolyl hydroxylases, is polyubiquinated, and eventually degraded in proteosomes.
- ID gène
- 3091
- UniProt
- Q16665
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, L'effet Warburg
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