HLA-DRB1 anticorps
Aperçu rapide pour HLA-DRB1 anticorps (ABIN238469)
Antigène
Voir toutes HLA-DRB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Attributs du produit
- Synonyms: MHC class II antigen DRB1, DR1, DR-1, HLA class II histocompatibility antigen, DRB1-1 betachain
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Purification
- Protein A affinity chromatography.
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Immunogène
- Purified, insoluble DR1 beta chain (DRB1*0101) expressed in E. coli inclusion bodies.
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Isotype
- IgG2b
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anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) (AA 30-266) antibody
HLA-DRB1 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) antibodyHLA-DRB1 Reactivité: Humain, Singe WB, FACS, IHC, IF Hôte: Souris Monoclonal LN-3 unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) (AA 27-264) antibodyHLA-DRB1 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) (AA 30-58) antibodyHLA-DRB1 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB21019 unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) antibodyHLA-DRB1 Reactivité: Humain WB, IHC, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) (AA 1-266) antibodyHLA-DRB1 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) antibodyHLA-DRB1 Reactivité: Humain IHC Hôte: Lapin Monoclonal 478R unconjugated Recombinant Antibody
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) antibodyHLA-DRB1 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) (AA 31-266) antibody (Biotin)HLA-DRB1 Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal Biotin
anti-Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1) (AA 30-266) antibodyHLA-DRB1 Reactivité: Humain WB, IF, ELISA Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western Blotting. Flow Cytometry: The antibody MEM-267 stains immature dendritic cells that express emptycell surface MHC molecules, but not cells that express predominantly peptide loadedforms. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4 containing 15 mM sodium azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))
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Autre désignation
- HLA Class II DR beta 1 / HLA-DRB1
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Sujet
- HLA-DR1 belongs to the HLA class II beta chain paralogues. The MHC Class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. MHC Class II molecules are expressed in antigen presenting cells (APC). The beta chain is approximately 26-28 kDa. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.Synonyms: DR-1, DR1, DRB1-1 beta chain, HLA class II histocompatibility antigen, MHC class II antigen DRB1
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UniProt
- P04229
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Pathways
- TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Antigène
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