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HLA-DRB1 anticorps (AA 30-58)

HLA-DRB1 Reactivité: Humain WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB21019 unconjugated
N° du produit ABIN390872
  • Antigène Voir toutes HLA-DRB1 Anticorps
    HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))
    Épitope
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 30-58
    Reactivité
    • 95
    • 31
    • 11
    • 11
    • 11
    • 11
    • 10
    • 8
    Humain
    Hôte
    • 53
    • 43
    Lapin
    Clonalité
    • 52
    • 44
    Polyclonal
    Conjugué
    • 41
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HLA-DRB1 est non-conjugé
    Application
    • 61
    • 45
    • 39
    • 25
    • 18
    • 18
    • 14
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This HLA-D_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids of human HLA-D_1.
    Clone
    RB21019
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HLA-DRB1 Anticorps primaire
  • Indications d'application
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))
    Autre désignation
    HLA-DRB1 (HLA-DRB1 Produits)
    Synonymes
    anticorps MGC108235, anticorps DRB1, anticorps DRw10, anticorps HLA-DR1B, anticorps HLA-DRB, anticorps SS1, anticorps major histocompatibility complex, class II, DR beta 1, anticorps hla-drb1, anticorps HLA-DRB1
    Sujet
    HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons.
    ID gène
    3123
    UniProt
    P04229
    Pathways
    TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Cancer Immune Checkpoints
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