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PABPC4 anticorps (Middle Region)

Il existe 2+ publications pour ce produit. L’anticorps anti-PABPC4 Polyclonal Lapin est utilisé pour la détection de PABPC4 dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Cheval et Lapin. Il a été validé pour WB.

1 image

(2 références)

N° du produit ABIN310043

150,78 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour PABPC4 anticorps (Middle Region) (ABIN310043)

Antigène

Voir toutes PABPC4 Anticorps

PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Reactivité

Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp PABPC4 est non-conjugé

Application

Western Blotting (WB)

Discover our top product PABPC4 Anticorps primaire

Épitope
7

3

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2

2

1

1

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1

1

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1
Middle Region

Séquence

RPNPRWQQGG RPQGFQGMPS AIRQSGPRPT LRHLAPTGSE CPDRLAMDFG

Homologie

Cow: 93%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit

This is a rabbit polyclonal antibody against PABPC4. It was validated on Western Blot using a cell lysate as a positive control.

Purification

Affinity Purified

Immunogène

The immunogen is a synthetic peptide directed towards the middle region of human PABPC4
anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 350-450) antibody
PABPC4 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (N-Term) antibody
PABPC4 Reactivité: Humain, Chien WB, IHC Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 18-229) antibody
PABPC4 Reactivité: Humain WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 181-230) antibody
PABPC4 Reactivité: Humain, Souris, Rat, Chien, Cheval, Singe, Roussette (Chauve-souris) WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (Internal Region) antibody
PABPC4 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IP Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 219-247) antibody
PABPC4 Reactivité: Humain WB Hôte: Lapin Polyclonal RB37035 unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 1-660) antibody
PABPC4 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (AA 432-481) antibody
PABPC4 Reactivité: Humain, Rat, Cobaye, Cheval, Lapin, Singe WB Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (Middle Region) antibody
PABPC4 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin WB Hôte: Lapin Polyclonal unconjugated

anti-Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4) (N-Term) antibody
PABPC4 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio) WB, IHC Hôte: Lapin Polyclonal unconjugated

Indications d'application

Optimal working dilutions should be determined experimentally by the investigator.

Commentaires

Antigen size: 644 AA

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation

Avoid repeated freeze-thaw cycles.

Stock

-20 °C

Stockage commentaire

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Liu, Yin, Wang, Ju, Chen, Qiu, Li, Peng, Lu: "Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis." dans: Journal of genetics and genomics = Yi chuan xue bao, Vol. 39, Issue 8, pp. 369-74, (2012) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
Antigène

PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Autre désignation

PABPC4

Sujet

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: APP-1, APP1, PABP4, iPABP
Protein Interaction Partner: FBXW11, UBC, IVNS1ABP, STAU1, RPA3, RPA2, RPA1, WWOX, SUZ12, RNF2, EZH2, BMI1, NCAPD2, DDX5, TARDBP, SRPK2, CLK3, YWHAQ, UBD, EIF2AK2, PAN2, UBL4A, SMAD9, ITGA4, IL7R, IFIT3, IFIT1, IFIT2, FN1, IGBP1, NUBP2, CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A,
Protein Size: 644

Poids moléculaire

71 kDa

ID gène

8761

NCBI Accession

NM_003819, NP_003810

UniProt

Q13310

Pathways

SARS-CoV-2 Protein Interactome