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STAT3 anticorps (pSer727)

Cet anticorps anti-STAT3 Polyclonal Lapin (Clone RB5791) (ABIN389664) détecte spécifiquement STAT3 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Western blot analysis of lysates from A431 cell line, untreated or treated with EGF, 100 ng/mL, 5 min,using Phospho-STAT3 Antibody (ABIN389664 and ABIN2839644) (upper) or tubulin (lower). (STAT3 anticorps (pSer727))

Fluorescent confocal image of SY5Y cells stained with phospho-STAT3- antibody. (STAT3 anticorps (pSer727))

Confocal immunofluorescent analysis of Phospho-STAT3- Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (STAT3 anticorps (pSer727))

4 images

N° du produit ABIN389664

434,77 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour STAT3 anticorps (pSer727) (ABIN389664)

Antigène

Voir toutes STAT3 Anticorps

STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))

Reactivité

Humain, Souris

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp STAT3 est non-conjugé

Application

Western Blotting (WB), Immunofluorescence (IF)

Clone

RB5791

Discover our top product STAT3 Anticorps primaire

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pSer727

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This STAT3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S727 of human STAT3.

Isotype

Ig Fraction
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (C-Term) antibody
KO Validated STAT3 Reactivité: Humain WB, IF, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pTyr705) antibody
STAT3 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IP, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pSer727) antibody
STAT3 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IP, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (C-Term) antibody
STAT3 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 640-770) antibody
STAT3 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pSer727) antibody
STAT3 Reactivité: Humain, Souris, Rat WB, IHC (p), FACS, IF (cc) Hôte: Lapin Monoclonal 4G1 unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 670-769) antibody
STAT3 Reactivité: Humain WB, ELISA, IF, PLA Hôte: Souris Monoclonal 4D6 unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (C-Term) antibody
Verified STAT3 Reactivité: Humain, Souris IHC, ELISA, IF, FACS Hôte: Chèvre Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 233-330) antibody
STAT3 Reactivité: Humain, Souris, Rat, Lapin WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pTyr705) antibody
STAT3 Reactivité: Humain, Souris, Rat, Porc, Lapin, Poulet WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

Indications d'application

IF: 1:100. IF: 1:10~50. IF: 1:200. WB: 1:500

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption

6 months
Antigène

STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))

Autre désignation

STAT3

Sujet

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. It mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein.

Poids moléculaire

88068

ID gène

6774

NCBI Accession

NP_003141, NP_644805, NP_998827

UniProt

P40763

Pathways

Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor