anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) Anticorps

The membrane-associated protein encoded by ABCA2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ABCA2 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCA2 20 Q9BZC7
ABCA2 11305  
ABCA2 79248 Q9ESR9
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Top anti-ABCA2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 77 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Chèvre Inconjugué ELISA   0.1 mg Connectez-vous pour afficher 3 to 5 Days
302,50 €
Détails
Chien Chèvre Inconjugué IHC (p), ELISA Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 3 to 4 Days
249,70 €
Détails
Humain Lapin Inconjugué IP Immunoprecipitation: ABCA2 Antibody [NBP1-30453] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-ABCA2 antibodyNBP1-30453 used for IP at 10 mcg/mg lysate. ABCA2 was also immunoprecipitated by rabbit anti-ABCA2 antibodyNBP1-30452, which recognizes an upstream epitope. 100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Lapin Inconjugué IP, WB Western Blot: ABCA2 Antibody [NBP1-30452] - Whole cell lysate from 293T cells. ABCA2 was also immunoprecipitated by rabbit anti-ABCA2 antibody NBP1-30453. 100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Lapin Inconjugué IHC (p), IP, IHC Immunohistochemistry-Paraffin: ABC2 Antibody [ABIN2616758] - FFPE section of human thyroid carcinoma. Antibody: Affinity purified rabbit anti-ABC2 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit 100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry-Paraffin: ABCA2 Antibody [NBP2-14249] Staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells. 0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Souris Rat PE FACS, WB   100 Tests Connectez-vous pour afficher 11 to 14 Days
530,79 €
Détails
Souris Rat PE FACS   100 Tests Connectez-vous pour afficher 11 to 14 Days
810,16 €
Détails

ABCA2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ABCA2 Anticorps mieux référencés

  1. Human Polyclonal ABCA2 Primary Antibody pour ELISA - ABIN451656 : Macé, Cousin, Ricard, Génin, Spanakis, Lafargue-Soubigou, Génin, Fournel, Roche, Haussy, Massey, Soubigou, Bréfort, Benoit, Brice, Campion, Hollis, Pradier, Benavides, Deleuze: ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease. dans Neurobiology of disease 2005 (PubMed)

Plus d’anticorps contre ABCA2 partenaires d’interaction

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) interaction partners

  1. Our findings indicate a considerable and direct relationship between mRNA expression levels of ABCA2, ABCA3 (Montrer ABCA3 Anticorps), MDR1 (Montrer TBC1D9 Anticorps), and MRP1 (Montrer MDM4 Anticorps) genes and positive minimal residual disease (MRD) measured after one year of treatment.

  2. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin (Montrer NCSTN Anticorps) maturation and intracellular localization.

  3. SLC2A1/GLUT1 (Montrer SLC2A1 Anticorps), SLC1A3/EAAT1 (Montrer SLC1A3 Anticorps), and SLC1A2/EAAT2 (Montrer SLC1A2 Anticorps) were the main SLC (Montrer CCL21 Anticorps) proteins whereas ABCG2/BCRP (Montrer ABCG2 Anticorps), ABCB1/MDR1 (Montrer ABCB4 Anticorps), ABCA2 and ABCA8 (Montrer ABCA8 Anticorps) were the main ABC (Montrer ABCB6 Anticorps) quantified in isolated brain microvessels

  4. A possible biochemical mechanism links ABCA2 expression, amyloid precursor protein (Montrer APP Anticorps) processing, and Alzheimer's disease.

  5. we demonstrate that ABCA2-deficiency inhibits prostate tumor metastasis in vivo and decreases chemotactic potential of cells

  6. roles for this largest known ABC (Montrer ABCB6 Anticorps) protein in neural transmembrane lipid export

  7. Reciprocal regulation of expression of the ABCA2 promoter by the early growth response-1 (Montrer EGR1 Anticorps) and Sp-family transcription factors.

  8. It is likely that expression of ABCA2 by two independent promoters constitutes locus of regulation controlling expression of the protein to meet requirements in different tissues.

  9. Increased expression of ABCA2 may be causally linked with altered expression of genes associated with the pathogenesis of Alzheimer disease.

  10. Among the 45 ABCA2 single nucleotide polymorphisms(SNPs) we tested, one synonymous SNP (rs908832) was found significantly associated with AD in both samples.

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) interaction partners

  1. Study suggests that ABCA2 modulation of sphingolipid metabolism activates a signaling pathway that regulates amyloid precursor protein (Montrer APP Anticorps) transcription

  2. control of ABCA2 expression level may be a key locus of regulation for esterification of plasma membrane-derived cholesterol through modulation of sphingolipid metabolism.

  3. Data from knockout mice suggest that Abca2 functions in penile erection; Abca2 knockout mice are more susceptible to estrogen-induced convulsions than wildtype mice; Abca2 appears to be involved in biotransformation of therapeutic estrogens.

  4. Lack of ABCA2 generates abnormalities in intracellular lipid distribution/trafficking in macrophages, increasing susceptibility to apoptosis in response to oxidized lipids and reduced atherosclerotic lesion development in LDL receptor (Montrer LDLR Anticorps) knockout mice.

  5. The ATP-binding cassette transporter-2 (ABCA2) is a key regulator of cholesterol homeostasis and low-density lipoprotein receptor (Montrer LDLR Anticorps) metabolism in neuronal cells.

  6. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin (Montrer NCSTN Anticorps) maturation and intracellular localization.

  7. ABC-me (Montrer ABCB10 Anticorps) is a novel gene that determines the ability to tolerate cardiac ischemia/reperfusion.

  8. ABCA2 has a role in myelin compaction in spinal cord and cerebrum, and in phenotypic tremor

  9. ABCA2 is expressed in non-myelin-forming as well as in myelin-forming Schwann cells. ABCA2 may be involved in transport of a substance associated with cellular maturation rather than initial myelin formation in both types of Schwann cells.

  10. ABCA2 is involved in the intracellular metabolism of sphingolipids in the brain, particularly SM and gangliosides in oligodendrocytes and certain neurons.

ABCA2 profil antigène

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ABCA2

  • ATP-binding cassette, sub-family A (ABC1), member 2 (ABCA2) anticorps
  • ATP-binding cassette, sub-family A (ABC1), member 2 (abca2) anticorps
  • SMG8 nonsense mediated mRNA decay factor (smg8) anticorps
  • ATP-binding cassette, sub-family A (ABC1), member 2 (Abca2) anticorps
  • ATP-binding cassette, subfamily A (ABC1), member 2 (Abca2) anticorps
  • Abc2 anticorps
  • AI413825 anticorps
  • c17orf71 anticorps
  • D2H0S1474E anticorps
  • mKIAA1062 anticorps
  • si:dkey-266h7.1 anticorps

Protein level used designations for ABCA2

ATP-binding cassette, sub-family A (ABC1), member 2 , ATP-binding cassette sub-family A member 2-like , protein smg-8 homolog , protein smg8 , smg-8 homolog, nonsense mediated mRNA decay factor , ATP-binding cassette 2 , ATP-binding cassette sub-family A member 2 , ATP-binding cassette transporter 2 , ATP-binding cassette, sub-family A, member 2

GENE ID SPECIES
100067889 Equus caballus
426955 Gallus gallus
100124617 Danio rerio
100231140 Taeniopygia guttata
100498548 Xenopus (Silurana) tropicalis
100017432 Monodelphis domestica
779744 Xenopus (Silurana) tropicalis
20 Homo sapiens
11305 Mus musculus
480669 Canis lupus familiaris
100299651 Bos taurus
79248 Rattus norvegicus
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