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anti-Coagulation Factor VIII (F8) Anticorps

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. De plus, nous expédions Factor VIII Kits (48) et Factor VIII Protéines (33) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
F8 14069 Q06194
F8 2157 P00451
F8 302470  
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Top anti-Factor VIII Anticorps sur anticorps-enligne.fr

Showing 10 out of 355 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué ELISA Detection limit for recombinant GST tagged F8 is approximately 3 ng/mL as a capture antibody. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Western Blot: Factor VIII antibody (S2194) [ABIN4493381] - in extracts from HuvEc cells. Immunocytochemistry/Immunofluorescence: Factor VIII Antibody [ABIN4493381] - Factor VIII antibody was tested 1:50 in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). Image objective 40x. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
451,25 €
Détails
Chien Lapin Inconjugué IF (p), IHC (p) Formalin-fixed and paraffin embedded rat tibia tissue labeled with Anti-Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed : Mouse C57 cells labeled with Anti- Factor VIII (FVIII) Polyclonal Antibody (ABIN668601) , Unconjugated at 1:300, followed by conjugation to the secondary antibody was Goat Anti-Rabbit IgG, PE conjugated  at 1:200 for 40 minutes at 37 °C DAPI (5 µg/mL, blue) was used to stain the cell nuclei 100 μL Connectez-vous pour afficher 5 to 7 Days
315,94 €
Détails
Humain Lapin Inconjugué IF (p), IHC (p) Formalin-fixed and paraffin embedded human skin labeled with Anti-Factor VIII Polyclonal Antibody, Unconjugated (ABIN872493) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 5 to 7 Days
315,94 €
Détails
Chien Lapin Inconjugué IHC, ELISA, WB 0.1 mg Connectez-vous pour afficher 6 to 11 Days
368,76 €
Détails
Humain Souris Inconjugué EIA, RIA, WB   0.5 mg Connectez-vous pour afficher 8 to 10 Days
605,00 €
Détails
Humain Lapin Inconjugué IF (cc), IF (p), IHC (p) Formalin-fixed and paraffin embedded:human colon carcinoma labeled with Anti-factor VIII(FVIII) (human) Polyclonal Antibody (ABIN728000), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded:human colon carcinoma labeled with Anti-factor VIII(FVIII)(human) Polyclonal Antibody , Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 5 to 7 Days
315,94 €
Détails
Humain Souris Inconjugué ELISA, WB Figure 1: Western blot analysis using F8 mouse mAb against truncated Trx-F8 recombinant protein (1) . 100 μL Connectez-vous pour afficher 6 to 8 Days
453,56 €
Détails
Humain Souris Inconjugué EIA, IHC (fro), WB   0.5 mg Connectez-vous pour afficher 8 to 10 Days
495,00 €
Détails
Humain Lapin Inconjugué WB Host: Rabbit  Target Name: F8  Sample Tissue: 721_B Whole Cell  Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 2 µg/mL Lysate Quantity: 241 µg/laneGel Concentration: 2.12 % 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails

F8 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Factor VIII Anticorps mieux référencés

  1. Human Monoclonal Factor VIII Primary Antibody pour ELISA - ABIN394620 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. dans Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN394620

  2. Dog (Canine) Polyclonal Factor VIII Primary Antibody pour IF (p), IHC (p) - ABIN668601 : Yu, Zhang, Jiang, Wang, Zhang: Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction. dans Molecular medicine reports 2015 (PubMed)
    Show all 3 references for ABIN668601

  3. Human Polyclonal Factor VIII Primary Antibody pour IF (cc), IF (p) - ABIN728000 : Zhou, Zhu, Zou, Wang: Changes in number and biological function of endothelial progenitor cells in hypertension disorder complicating pregnancy. dans Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2008 (PubMed)
    Show all 2 references for ABIN728000

  4. Human Monoclonal Factor VIII Primary Antibody pour ELISA, WB - ABIN969123 : Shovlin, Sulaiman, Govani, Jackson, Begbie: Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism. dans Thrombosis and haemostasis 2007 (PubMed)
    Show all 2 references for ABIN969123

  5. Human Monoclonal Factor VIII Primary Antibody pour EIA, RIA - ABIN120341 : Rotblat, OBrien, OBrien, Goodall, Tuddenham: Purification of human factor VIII:C and its characterization by Western blotting using monoclonal antibodies. dans Biochemistry 1985 (PubMed)
    Show all 2 references for ABIN120341

  6. Human Polyclonal Factor VIII Primary Antibody pour IF (p), IHC (p) - ABIN872493 : Tang, Liu, Dong, Li, Li, Hou, Zheng, Lin, Ren: Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts. dans Inflammation 2014 (PubMed)
    Show all 2 references for ABIN872493

  7. Human Polyclonal Factor VIII Primary Antibody pour ICC, IF - ABIN449338 : Zhu, Liu, Miao, Qu, Chi: Enhanced plasma factor VIII activity in mice via cysteine mutation using dual vectors. dans Science China. Life sciences 2012 (PubMed)
    Show all 2 references for ABIN449338

  8. Human Monoclonal Factor VIII Primary Antibody pour EIA, IHC (fro) - ABIN112268 : Stel, van der Kwast, Veerman: Detection of factor VIII/coagulant antigen in human liver tissue. dans Nature 1983 (PubMed)

  9. Dog (Canine) Polyclonal Factor VIII Primary Antibody pour IHC, ELISA - ABIN1582291 : Shen, Li, Chung, Gillies: Retinal vascular changes after glial disruption in rats. dans Journal of neuroscience research 2010 (PubMed)

Plus d’anticorps contre Factor VIII partenaires d’interaction

Zebrafish Coagulation Factor VIII (F8) interaction partners

  1. gene is flanked by factor VII (Montrer TH Anticorps) and factor X genes; gene encodes a protein homologous to factor VII (Montrer TH Anticorps), but lacks critical residues for factor VII (Montrer TH Anticorps) activity; functions as an inhibitor of blood coagulation in biochemical assays using zebrafish or human plasmas

Mouse (Murine) Coagulation Factor VIII (F8) interaction partners

  1. data demonstrate that infusion of platelets containing FVIII triggers neither primary nor memory anti-FVIII immune response in FVIII(null) mice

  2. Both platelet-VWF (Montrer VWF Anticorps) and plasma-VWF (Montrer VWF Anticorps) are required for optimal platelet-derived FVIII gene therapy for hemophilia A in the presence of inhibitors.

  3. These data support the investigation of FVIII orthologs as treatment modalities in both the congenital and acquired FVIII inhibitor settings.

  4. Activatable bioengineered FIX molecules with FVIII-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  5. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (Montrer LRP1 Anticorps) cluster III.

  6. a fragment containing only approximately 20% of the VWF (Montrer VWF Anticorps) sequence is sufficient to support FVIII stability in vivo

  7. Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII pool in the mouse.

  8. Endothelial cells are the predominant, and possibly exclusive, source of plasma FVIII.

  9. Micro-computed tomography analysis of distal tibia metaphyses also revealed for the first time a major impact of the FVIII/thrombin (Montrer F2 Anticorps)/PAR1 (Montrer F2R Anticorps) axis on the dynamic bone structure, showing reduced bone.

  10. Findings indicate that improving protein trans-splicing by inter-chain disulfide bonding is a promising approach for increasing the efficacy of dual-vector based FVIII gene transfer.

Human Coagulation Factor VIII (F8) interaction partners

  1. von Willebrand factor (Montrer VWF Anticorps) binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

  2. Desmopressin acetate increases F8 plasma concentration in patients with combined deficiency of factors V and VIII (Montrer COX8A Anticorps).

  3. 37 (70%) of the 53 had discordant antigen-activity ratio, majority of those mutations produced FVIII with low FVIII-specific activity. However, 4 (7.5%) of the 53 mutations produced higher specific activity of FVIII. It is possible that these mutations either produce a secretory defect or an increased metabolic turnover to account for the low levels of FVIII with these mutations.

  4. Platelet-targeted FVIII gene therapy has higher therapeutic efficacy compared to factor VIII replacement therapy may be due to accelerated thrombin (Montrer F2 Anticorps) generation.

  5. Letter: report deep intronic variants of factor VII (Montrer TH Anticorps) gene in hemophilia A.

  6. Coagulation test results showed that the presence of double Glu113Asp, Arg593Cys mutations has a slightly synergistic effect on FVIII activity.

  7. Report a dose-response relationship between high FVIII levels and risk of death in venous thrombosis patients and in individuals from the general population.

  8. Case Report: P1809L mutation in A3 induced the conformational change in the FVIII molecule that hampered antigenic determinant(s) located in the C2 domain and might result in the inhibitor development.

  9. FVIII predicted venous thrombosis recurrence in a dose-response fashion, overall and in several subgroups, and is a strong candidate component of recurrence prediction tools.

  10. Interaction between VWF (Montrer VWF Anticorps) and FVIII in treating VWD (Montrer VWF Anticorps).

Pig (Porcine) Coagulation Factor VIII (F8) interaction partners

  1. thrombin (Montrer F2 Anticorps) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (Montrer UGDH Anticorps) and by receptor-mediated up-regulation of factor XIII (Montrer UGDH Anticorps) synthesis

  2. cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Coagulation Factor VIII (F8) interaction partners

  1. Factor VIIIc (Montrer COX7A2 Anticorps) is responsible for tissue invasion during tumor progression.

Factor VIII (F8) profil antigène

Profil protéine

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Gene names and symbols associated with F8

  • coagulation factor VIIi (f7i) anticorps
  • coagulation factor VIII (F8) anticorps
  • coagulation factor VIII, procoagulant component (F8) anticorps
  • AHF anticorps
  • Cf-8 anticorps
  • Cf8 anticorps
  • DXS1253E anticorps
  • F8B anticorps
  • F8C anticorps
  • fb61d02 anticorps
  • FVIII anticorps
  • HEMA anticorps
  • wu:fb61d02 anticorps

Protein level used designations for F8

Factor VIII , procoagulant component , antihemophilic factor , coagulation factor VIII , coagulation factor VIIIc , factor VIII F8B , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII , coagulation co-factor

GENE ID SPECIES
282671 Danio rerio
14069 Mus musculus
2157 Homo sapiens
397339 Sus scrofa
403875 Canis lupus familiaris
100271720 Bos taurus
100303761 Oryctolagus cuniculus
302470 Rattus norvegicus
100359363 Ovis aries
422199 Gallus gallus
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