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The protein encoded by GDF10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. De plus, nous expédions Growth Differentiation Factor 10 Anticorps (81) et Growth Differentiation Factor 10 Protéines (22) et beaucoup plus de produits pour cette protéine.
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Study shows that GDF10 is down-regulated in patients with oral squamous cell carcinoma, and is an independent risk factor for overall survival. Its expression is regulated by TGFBR3 (Montrer TGFBR3 Kits ELISA) which shares the signaling inhibiting epithelial-mesenchymal transition.
GDF10 is a stroke-induced signal for axonal sprouting and functional recovery.
new hypoxia-inducible and SOX9 (Montrer SOX9 Kits ELISA)-regulated genes, Gdf10 and Chm-I (Montrer LECT1 Kits ELISA). In addition, Mig6 (Montrer ERRFI1 Kits ELISA) and InhbA (Montrer INHBA Kits ELISA) were induced by hypoxia, predominantly via HIF-2alpha (Montrer EPAS1 Kits ELISA)
BMP3b and BMP6 (Montrer BMP6 Kits ELISA) genes were suppressed by DNA methylation (Montrer HELLS Kits ELISA) and methylation of BMP3b is significantly frequent in Japanese malignant pleural mesotheliomas (MPMs), suggesting its pathogenic role and the ethnic difference in MPMs.
Results show that Gdf10, expressed in Bergmann glial cells, is affected by the loss of Shh (Montrer SHH Kits ELISA) as early as E18.5, suggesting a regulation of glial development by Shh (Montrer SHH Kits ELISA)
Here we show that Runx2 (Montrer RUNX2 Kits ELISA) is highly expressed in lung cancer cells and downregulates BMP-3B. The ectopic expression of Runx2 (Montrer RUNX2 Kits ELISA), but not DNA binding mutant Runx2 (Montrer RUNX2 Kits ELISA), in normal lung fibroblast cells and lung cancer cells resulted in suppression of BMP-3B levels.
data suggest that BMP-3b is secreted from adipocytes, is involved in adipocyte differentiation, and inhibits adipogenesis as a unique complex.
Sca-1 (Montrer Ly6a Kits ELISA) attenuated GDF10-dependent TGF-beta (Montrer TGFB1 Kits ELISA) signaling by disrupting the heterodimerization of TbetaRI (Montrer TGFBR1 Kits ELISA) and TbetaRII receptors.
Gdf10 is expressed in Bergmann glia and is reduced in staggerer mice.
GDF10 gene might have potential effects on body measurement traits in the above mentioned cattle populations and could be used for marker-assisted selection.
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.
growth differentiation factor 10
, bone morphogenetic protein 3B-like
, bone morphogenetic protein 3B
, bone-inducing protein
, prepro bone inducing protein
, growth/differentiation factor 10