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LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. De plus, nous expédions Loricrin Kits (6) et Loricrin Protéines (4) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 19 products:
Chemical Polyclonal LOR Primary Antibody pour ICC, IF - ABIN443470
Shigehara, Okuda, Nemer, Chedraoui, Hayashi, Bitar, Nakai, Abbas, Daou, Abe, Sleiman, Kibbi, Kurban, Shimomura: Mutations in SDR9C7 gene encoding an enzyme for vitamin A metabolism underlie autosomal recessive congenital ichthyosis. dans Human molecular genetics 2016
the late cornified envelope 1 proteins are regulated by NRF2 (Montrer NFE2L2 Anticorps) and are compensatory components for loricrin as determined by their localization within the loricrin knockout cell envelope via immunoelectron microscopy
Oct-6 (Montrer POU3F1 Anticorps) and Oct-11 (Montrer POU2F3 Anticorps) contribute to the regulation of loricrin gene transcription via interaction with AP-1 (Montrer JUN Anticorps) factors and Sp1 (Montrer SP1 Anticorps)/Sp3 (Montrer SP3 Anticorps).
In the absence of loricrin, S. aureus nasal colonisation was significantly impaired.
The decreased expression of epidermal growth factor receptor (EGFR (Montrer EGFR Anticorps)), E-cadherin (Montrer CDH1 Anticorps), occludin (Montrer OCLN Anticorps), and SIRT1 (Montrer SIRT1 Anticorps) in the skin of Flg(ft (Montrer FLG Anticorps)) mice, compared with those in C57BL/6J mice, is reported.
YY1 (Montrer YY1 Anticorps) contributes to specific loricrin gene expression in differentiated keratinocytes by suppression of its transcription in undifferentiated keratinocytes.
nectin-1 (Montrer PVRL1 Anticorps) plays a key role in the expression of loricrin in the epidermis
Skin biopsies from STAT6 transgenic mice (Montrer IVL Anticorps)were deficient in the expression and production of loricrin and involucrin.
These results indicate AASS (Montrer AASS Anticorps) knockdown decreases the lysine requirement of the cell via a reduction of lysine catabolism through the saccharopine pathway.
Mice receiving the high-protein diet had greater AASS (Montrer AASS Anticorps) mRNA compared to mice fed the adequate protein diet.
Authors report a multi-generation family with prominent ichthyosis (Montrer LBR Anticorps) and palmoplantar involvement due to a novel mutation in loricrin.
Letter: Knockdown of either filaggrin (Montrer FLG Anticorps) or loricrin increases the productions of interleukin (IL)-1alpha, IL-8 (Montrer IL8 Anticorps), IL-18 (Montrer IL18 Anticorps) and granulocyte macrophage colony-stimulating factor (Montrer CSF2 Anticorps) in stratified human keratinocytes.
Studies on human keratinocytes recognized that loricrin expression was inversely related to the expression of the cyclin-dependent kinase (Montrer CDK1 Anticorps) inhibitor p21 (Montrer CDKN1A Anticorps)
two novel heterozygous frameshift mutations in exon 2 - c.646_647insGCAGCAGGTC, p.Gln216Argfs*123 and c.798_799dupT, p.Gly267Trpfs*69 in loricrin keratoderma patients
Results describe a novel frameshift mutation leading to loricrin keratoderma presenting with colloidion membrane
We found no mutations of Loricrin in two Progressive symmetrical erythrokeratoderma families.
We describe a young man who was a collodion baby and had the typical presentation of Loricrin keratoderma. Direct DNA sequencing identified a heterozygous mutation in the loricrin gene with a single G insertion, 730insG, present in (a) the patient
There were no mutations found in the LOR gene and the true pathogenesis of progressive symmetrical erythrokeratodermia remains unknown.
identified mRNA transcripts from three genes CDSN (Montrer CDSN Anticorps), LOR and KRT9 (Montrer KRT9 Anticorps), showing strong over-expression in skin samples relative to samples from forensic body fluids, making them suitable markers for skin identification
VEGF (Montrer VEGFA Anticorps) release and the subsequent activation of VEGF receptor 2 link loricrin gene mutations to rapid cell proliferation in a cellular model of loricrin keratoderma.
This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.
, alpha-aminoadipic semialdehyde synthase, mitochondrial
, lysine oxoglutarate reductase
, saccharopine dehydrogenase