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anti-Treacher Collins-Franceschetti Syndrome 1 (TCOF1) Anticorps

TCOF1 encodes a nucleolar protein with a LIS1 homology domain. De plus, nous expédions Treacher Collins-Franceschetti Syndrome 1 Protéines (4) et Treacher Collins-Franceschetti Syndrome 1 Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
Anti-Rat TCOF1 TCOF1 291571  
TCOF1 21453 O08784
TCOF1 6949 Q13428
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Top anti-Treacher Collins-Franceschetti Syndrome 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 34 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from Jurkat/293/HeLa cells, using TC... Immunohistochemistry analysis of paraffin-embedded human lung carcinom... 100 μg Connectez-vous pour afficher 6 to 8 Days
314,29 €
Détails
Humain Lapin Inconjugué IHC (p), ELISA, WB 50 μL Connectez-vous pour afficher 11 to 14 Days
501,70 €
Détails
Humain Souris Inconjugué WB Western Blot analysis of TCOF1 expression in transfected 293T cell lin... 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué ChIP, IC, IF, IHC, WB Immunofluorescent analysis of TCOF1 staining in HEK293T cells. Formali... Immunohistochemical analysis of TCOF1 staining in human breast cancer ... 200 μL Connectez-vous pour afficher 7 to 8 Days
464,29 €
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of extracts from Jurkat/293/HeLa cells, using TC... 50 μg Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Xenopus laevis Souris Inconjugué IHC (fro), IF, WB   5 mL Connectez-vous pour afficher 8 to 10 Days
253,00 €
Détails
Humain Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 12 Days
299,73 €
Détails
Humain Lapin Inconjugué IHC, ELISA, WB 100 μg Connectez-vous pour afficher 15 to 21 Days
419,39 €
Détails
Humain Lapin Inconjugué ELISA, IF, IHC, WB   100 μL Connectez-vous pour afficher 13 Days
176,62 €
Détails
Humain Lapin Inconjugué IP Immunoprecipitation of TCOF1 transfected lysate using anti-TCOF1 MaxPa... 100 μL Connectez-vous pour afficher 8 to 9 Days
358,40 €
Détails

TCOF1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité
Mouse (Murine) , , ,

Human , , , ,
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anti-Treacher Collins-Franceschetti Syndrome 1 Anticorps mieux référencés

  1. Xenopus laevis Monoclonal TCOF1 Primary Antibody pour IHC (fro), IF - ABIN126712 : Derenzini, Romagnoli, Mingazzini, Marinozzi: Interphasic nucleolar organizer region distribution as a diagnostic parameter to differentiate benign from malignant epithelial tumors of human intestine. dans Virchows Archiv. B, Cell pathology including molecular pathology 1988 (PubMed)
    Show all 3 references for ABIN126712

  2. Human Polyclonal TCOF1 Primary Antibody pour IHC, ELISA - ABIN1533867 : So, Gonzales, Henning, Dixon, Dixon, Valdez: Another face of the Treacher Collins syndrome (TCOF1) gene: identification of additional exons. dans Gene 2004 (PubMed)

Plus d’anticorps contre Treacher Collins-Franceschetti Syndrome 1 partenaires d’interaction

Mouse (Murine) Treacher Collins-Franceschetti Syndrome 1 (TCOF1) interaction partners

  1. Tcof1 acts as a modifier of Pax3 (Montrer PAX3 Anticorps) during enteric nervous system development.

  2. identified Tcof1 as an important regulator of vagal neural crest cells (NCC (Montrer SLC12A3 Anticorps)) development and enteric nervous system formation; Tcof1 loss-of-function results in a deficiency of vagal NCC (Montrer SLC12A3 Anticorps) and their delayed colonization of the gut (Montrer GUSB Anticorps) during early embryogenesis, which mimics the early stages of Hirschsprung's disease

  3. our research has therefore identified Treacle and as novel in vivo regulators of spindle fidelity, mitotic progression, and proliferation in the maintenance and localization of neural progenitor cells.

  4. Loss-of-function mutation in Tcof1 results in defects in middle ear postnatal development and conductive hearing loss.

  5. Results show that treacle is involved in ribosomal DNA gene transcription by interacting with upstream binding factor (UBF (Montrer UBTF Anticorps)).

  6. Data show that Tcof1 and treacle synthesis play an important role in the proliferation of neuroblastoma (Montrer ARHGEF16 Anticorps) cells.

  7. Analysis of RNA isolated from wild-type and Tcof1+/- heterozygous mice embryos from strains that exhibit a lethal phenotype showed significant reduction in 2'-O-methylation at nucleotide C463 of 18S rRNA

  8. A minimal promoter fragment from -253 to +43 bp (Montrer EIF4EBP1 Anticorps) directs constitutive expression in both cell types, and dual regulation of Tcof1 appears to be through differential repression of this minimal promoter.

  9. It has been hypothesized that mutations in Tcof1 disrupt ribosome biogenesis to a degree that is insufficient to meet the proliferative needs of the neuroepithelium and neural crest cells.

Human Treacher Collins-Franceschetti Syndrome 1 (TCOF1) interaction partners

  1. Autosomal recessive POLR1D (Montrer POLR1D Anticorps) mutation with decrease of TCOF1 mRNA is responsible for Treacher Collins syndrome.

  2. findings identify TCOF1 as a DDR (Montrer DDR1 Anticorps) factor that could cooperate with ATM (Montrer ATM Anticorps) and NBS1 (Montrer NBN Anticorps) to suppress inappropriate rDNA transcription and maintain genomic integrity after DNA damage.

  3. we describe for the first time, two patients with MFD (Montrer SCYL1 Anticorps) and ID and for whom a deletion encompassing TCOF1 and CAMK2A (Montrer CAMK2A Anticorps) has been identified

  4. Mutations in TCOF1, POLR1C (Montrer POLR1C Anticorps) and POLR1D (Montrer POLR1D Anticorps) have all been implicated in causing TCS

  5. Treacle-mediated NBS1 (Montrer NBN Anticorps) recruitment into the nucleoli regulates rRNA silencing in trans in the presence of distant chromosome breaks.

  6. TCOF1 genetic mutation can be a cause of Treacher Collins syndrome in Chinese patients.

  7. Presents the case of a male with Treacher Collins syndrome with a heterozygous de novo frameshift mutation within the TCOF1 gene (c.790_791delAG,p.Ser264GlnfsX7), as well as findings from three other individuals from two families with the same mutation.

  8. 6 of 12 patients diagnosed with hemifacial microsomia exhibited a novel frameshift mutation c. 4127 ins (Montrer INS Anticorps) G in exon 24 in the TCOF1 gene.

  9. Gene rearrangements in TCOF1 are responsible for Treacher-Collins-Franceschetti syndrome.

  10. We demonstrated that adult leucocytes and mesenchymal cells from TCS patients present significantly reduced levels of TCOF1

Treacher Collins-Franceschetti Syndrome 1 (TCOF1) profil antigène

Profil protéine

This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TCOF1

  • Treacher Collins-Franceschetti syndrome 1 (Tcof1) anticorps
  • Treacher Collins-Franceschetti syndrome 1 (TCOF1) anticorps
  • Treacher Collins-Franceschetti syndrome 1 (LOC100226238) anticorps
  • Treacher Collins-Franceschetti syndrome 1 (LOC100341764) anticorps
  • Treacher Collins Franceschetti syndrome 1, homolog (Tcof1) anticorps
  • AA408847 anticorps
  • AW209012 anticorps
  • MFD1 anticorps
  • TCOF1 anticorps
  • TCS1 anticorps
  • treacle anticorps

Protein level used designations for TCOF1

Treacher Collins Franceschetti syndrome 1, homolog , Treacher Collins-Franceschetti syndrome 1 homolog , treacle protein , tcof1 gene exons 14-15-16a-16b , tcof1 gene exons 7-13 , treacle , Treacher Collins-Franceschetti syndrome 1 , treacle protein-like , treacher Collins syndrome protein homolog , Treacher Collins syndrome protein , nucleolar trafficking phosphoprotein

GENE ID SPECIES
291571 Rattus norvegicus
403592 Canis lupus familiaris
416276 Gallus gallus
471696 Pan troglodytes
513591 Bos taurus
664735 Macaca mulatta
100060348 Equus caballus
100226238 Taeniopygia guttata
100341764 Oryctolagus cuniculus
100435631 Pongo abelii
100471510 Ailuropoda melanoleuca
100591432 Nomascus leucogenys
21453 Mus musculus
6949 Homo sapiens
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