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anti-WW Domain Containing Transcription Regulator 1 (WWTR1) Anticorps

WWTR1 encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. De plus, nous expédions WWTR1 Protéines (5) et WWTR1 Kits (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
WWTR1 25937 Q9GZV5
WWTR1 97064 Q9EPK5
WWTR1 295062  
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Top anti-WWTR1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 51 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-WWTR1 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué EIA, WB WWTR1 Antibody (C-term) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the WWTR1 antibody detected the WWTR1 protein (arrow). 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué WB Western Blot: TAZ Antibody [ABIN153163] - Western blot analysis of TAZ in MDCK cells using ABIN153163 at 1:250 dilution. 0.1 mg Connectez-vous pour afficher 3 to 5 Days
363,75 €
Détails
Humain Lapin Inconjugué ChIP, ICC, IF, IHC (p), IP, SimWes, WB Detection of ABIN258561 protein using ABIN258561 on HEK 293 cell lysate. Simple Western: TAZ/WWTR1 Antibody [ABIN2585619] - Simple Western lane view shows a specific band for TAZ in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. 0.1 mL Connectez-vous pour afficher 3 to 5 Days
426,25 €
Détails
Humain Lapin Inconjugué WB WWTR1 Antibody (C-term)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the WWTR1 antibody detected the WWTR1 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Souris Inconjugué IHC, WB Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-WWTR1 mouse monoclonal antibody. (ABIN2455017) HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY WWTR1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-WWTR1. 100 μL Connectez-vous pour afficher 6 to 8 Days
366,67 €
Détails
Humain Souris Inconjugué FACS, IF, WB HEK293T cells transfected with either RC204082 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-WWTR1 antibody (ABIN2454926), and then analyzed by flow cytometry. Anti-WWTR1 mouse monoclonal antibody (ABIN2454926) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY WWTR1 (RC204082). 100 μL Connectez-vous pour afficher 6 to 8 Days
366,67 €
Détails
Humain Souris Inconjugué FACS, IF, WB HEK293T cells transfected with either RC204082 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-WWTR1 antibody (ABIN2454960), and then analyzed by flow cytometry. Anti-WWTR1 mouse monoclonal antibody (ABIN2454960) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY WWTR1 (RC204082). 100 μL Connectez-vous pour afficher 6 to 8 Days
418,10 €
Détails
Humain Souris Inconjugué FACS, IF, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails
Humain Souris Inconjugué IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails

WWTR1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,
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Mouse (Murine)
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Rat (Rattus)


anti-WWTR1 Anticorps mieux référencés

  1. Human Polyclonal WWTR1 Primary Antibody pour WB - ABIN153163 : Chan, Lim, Guo, Ng, Lee, Hunziker, Zeng, Hong: A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. dans Cancer research 2008 (PubMed)
    Show all 7 references for ABIN153163

  2. Human Polyclonal WWTR1 Primary Antibody pour ChIP, ICC - ABIN258561 : Strakova, Reed, Ihnatovych: Human transcriptional coactivator with PDZ-binding motif (TAZ) is downregulated during decidualization. dans Biology of reproduction 2010 (PubMed)
    Show all 5 references for ABIN258561

  3. Human Polyclonal WWTR1 Primary Antibody pour EIA, WB - ABIN955592 : Remue, Meerschaert, Oka, Boucherie, Vandekerckhove, Sudol, Gettemans: TAZ interacts with zonula occludens-1 and -2 proteins in a PDZ-1 dependent manner. dans FEBS letters 2010 (PubMed)
    Show all 5 references for ABIN955592

  4. Cow (Bovine) Polyclonal WWTR1 Primary Antibody pour WB - ABIN2779708 : Hong, Hwang, McManus, Amsterdam, Tian, Kalmukova, Mueller, Benjamin, Spiegelman, Sharp, Hopkins, Yaffe: TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. dans Science (New York, N.Y.) 2005 (PubMed)

Plus d’anticorps contre WWTR1 partenaires d’interaction

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Yap (Montrer YAP1 Anticorps)/Taz (Montrer TAZ Anticorps)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  2. Taz (Montrer TAZ Anticorps) is required in the anteroposterior patterning of the pronephric progenitor domain in the intermediate mesoderm, acting in part by regulating retinoic acid signaling in the pronephric progenitor field in the intermediate mesoderm.

  3. Taz (Montrer TAZ Anticorps)-depleted larvae displayed patterning defects in ventral cranial vessels that correlate with lateral displacement of thyroid follicles

  4. When transcriptional coactivators Yap (Montrer YAP1 Anticorps) and Taz (Montrer TAZ Anticorps) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  5. TAZ (Montrer TAZ Anticorps) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. SCLC cell lines of the YAP (Montrer YAP1 Anticorps)/TAZ (Montrer TAZ Anticorps) subgroup had higher sensitivity to the widely used anticancer agent for SCLC, topotecan.

  2. The activity of the YAP (Montrer YAP1 Anticorps)/TAZ (Montrer TAZ Anticorps) transcriptional coactivators, was found to be regulated by metabolic pathways, such as aerobic glycolysis and mevalonate synthesis, and by the nutrient-sensing LKB1 (Montrer STK11 Anticorps)-AMPK (Montrer PRKAA1 Anticorps) and TSC (Montrer SLC12A3 Anticorps)-mTOR (Montrer FRAP1 Anticorps) pathways. (Review)

  3. Over expression of TAZ (Montrer TAZ Anticorps) was associated with abnormal expression of beta-catenin (Montrer CTNNB1 Anticorps), which is correlated with poor prognosis of patients with adenocarcinoma of the esophagogastric junction

  4. Our findings emphasize the tumorigenic role of TAZ (Montrer TAZ Anticorps) and may serve as the basis for new treatment strategies.

  5. Immortalized fibroblasts conditionally expressing active YAP (Montrer YAP1 Anticorps) or TAZ (Montrer TAZ Anticorps) mutant proteins overcome soft matrix limitations on growth and promote fibrosis

  6. Results revealed that TAZ (Montrer TAZ Anticorps) is a differentially expressed molecule in human hepatocellular carcinoma (HCC (Montrer FAM126A Anticorps)) suggesting it as an important regulator, TAZ (Montrer TAZ Anticorps) might be as a new diagnostic biomarker in HCC (Montrer FAM126A Anticorps).

  7. Results show TAZ (Montrer TAZ Anticorps) functioned as an oncogene (Montrer RAB1A Anticorps) and promoted pancreatic cancer epithelial-mesenchymal transition and progression.

  8. this article summarizes the current understanding of the biological functions of YAP (Montrer YAP1 Anticorps) and TAZ (Montrer TAZ Anticorps), and how the regulation of these two proteins can be disrupted in cancer.[Review][

  9. TAZ (Montrer TAZ Anticorps) inhibits temozolomide induced apoptosis via upregulation of MCL-1 (Montrer MCL1 Anticorps) (myeloid cell leukemia 1) and high expression of TAZ (Montrer TAZ Anticorps) predicts a poor prognosis for GBM patients

  10. TAZ (Montrer TAZ Anticorps) and YAP (Montrer YAP1 Anticorps) are differentially regulated by hypoxia in cancer cells

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Results found that sclerostin (Montrer SOST Anticorps) enhances adipocyte differentiation in 3T3-L1 cells and reduced TAZ (Montrer TAZ Anticorps)-responsive transcriptional activity and TAZ (Montrer TAZ Anticorps)-responsive gene expression, indicating a role for TAZ (Montrer TAZ Anticorps) as a regulator of adipogenesis by sclerostin (Montrer SOST Anticorps).

  2. Expression of TAZ (Montrer TAZ Anticorps) promotes embryonic neural stem cell maintenance by enhancing stemness of neural stem cells during mammalian brain development.

  3. Tead2 (Montrer TEAD2 Anticorps) transcription factors are crucial regulators of the cellular distribution of Yap (Montrer YAP1 Anticorps) and Taz (Montrer TAZ Anticorps), and together they control the expression of genes critical for EMT (Montrer ITK Anticorps) and metastasis.

  4. findings uncover important roles for Yap (Montrer YAP1 Anticorps) and Taz (Montrer TAZ Anticorps) in cranial neural crest diversification and development

  5. Study discovered that YAP (Montrer YAP1 Anticorps)/TAZ (Montrer TAZ Anticorps) are bona fide downstream effectors of the alternative Wnt (Montrer WNT2 Anticorps) signaling pathway.

  6. Hippo signalling effectors, YAP (Montrer YAP1 Anticorps) and TAZ (Montrer TAZ Anticorps), promote both the proliferation of intestinal stem/progenitor cells and their differentiation into goblet cells.

  7. This study identifies a novel mechanism of TAZ (Montrer TAZ Anticorps) regulation by YAP (Montrer YAP1 Anticorps), which has significant implications for our understanding of Hippo pathway regulation, YAP (Montrer YAP1 Anticorps)-isoform specific signaling, and the role of these proteins in cell proliferation, apoptosis, and tumorigenesis

  8. Disrupting Yap (Montrer YAP1 Anticorps)/Taz (Montrer TAZ Anticorps) activities enhances Ret (Montrer RET Anticorps) pathway activity and contributes to pathogenesis of lower urinary tract defects

  9. Immortalized fibroblasts conditionally expressing active YAP (Montrer YAP1 Anticorps) or TAZ (Montrer TAZ Anticorps) mutant proteins overcome soft matrix limitations on growth and promote fibrosis

  10. YAP (Montrer YAP1 Anticorps)/TAZ (Montrer TAZ Anticorps) regulate transcriptional elongation from the enhancer elements by recruiting the Mediator complex and promoting phenotypes of overgrowth and tumorigenesis

WWTR1 profil antigène

Profil protéine

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Gene names and symbols associated with WWTR1

  • WW domain containing transcription regulator 1 (wwtr1) anticorps
  • WW domain containing transcription regulator 1 (WWTR1) anticorps
  • WW domain containing transcription regulator 1 (Wwtr1) anticorps
  • 2310058J06Rik anticorps
  • 2610021I22Rik anticorps
  • C78399 anticorps
  • Taz anticorps
  • WWTR1 anticorps

Protein level used designations for WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPECIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
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