phosphofurin Acidic Cluster Sorting Protein 2 Protéines (PACS2)

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. De plus, nous expédions PACS2 Anticorps (25) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
PACS2 23241 Q86VP3
PACS2 217893  
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Top PACS2 Protéines sur anticorps-enligne.fr

Showing 4 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 67 Days
10.536,00 €
Détails
Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 67 Days
10.536,00 €
Détails
HOST_HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher 6 to 8 Days
748,00 €
Détails
HOST_Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 7 to 8 Days
345,60 €
Détails

PACS2 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) partenaires d'interaction

Human phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) interaction partners

  1. cIAPs constitutively downregulate PACS-2 by polyubiquitination and proteasomal degradation, thereby restraining TRAIL-induced killing of liver cancer cells

  2. Tumor necrosis factor (Montrer TNF Protéines)-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2.

  3. subcellular localization and function of polycystin-2 (Montrer PKD2 Protéines) are directed by phosphofurin acidic cluster sorting protein (PACS)-1 and PACS-2

  4. PACS-2 as a novel sorting protein that links the endoplasmic reticulum (ER)-mitochondria axis to ER homeostasis

  5. PACS-2 is required for Nef action and sorting of itinerant membrane cargo in the TGN (Montrer TG Protéines)/endosomal system

  6. the phosphorylation state of the calnexin (Montrer CANX Protéines) cytosolic domain and its interaction with PACS-2 sort the chaperone between domains of the ER and the plasma membrane

  7. Results identify PACS-2 as an essential TRAIL effector, and show that Akt (Montrer AKT1 Protéines) cooperates with 14-3-3 (Montrer YWHAQ Protéines) to regulate the homeostatic and apoptotic properties of PACS-2 that mediate TRAIL action.

Mouse (Murine) phosphofurin Acidic Cluster Sorting Protein 2 (PACS2) interaction partners

  1. CS-2 (Montrer MYOZ1 Protéines) traffics to the nucleus where it regulates SIRT1 (Montrer SIRT1 Protéines)-mediated p53 (Montrer TP53 Protéines) deacetylation. PACS-2 binds SIRT1 (Montrer SIRT1 Protéines) in vitro and directly inhibits SIRT1 (Montrer SIRT1 Protéines)-catalyzed p53 (Montrer TP53 Protéines) deacetylation.

  2. PACS-2 is required for Nef action and sorting of itinerant membrane cargo in the TGN (Montrer TG Protéines)/endosomal system

  3. Results identify PACS-2 as an essential TRAIL effector, and show that Akt (Montrer AKT1 Protéines) cooperates with 14-3-3 (Montrer YWHAQ Protéines) to regulate the homeostatic and apoptotic properties of PACS-2 that mediate TRAIL action.

Profil protéine PACS2

Profil protéine

Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Gene names and symbols associated with PACS2

  • phosphofurin acidic cluster sorting protein 2 (PACS2)
  • phosphofurin acidic cluster sorting protein 2 (Pacs2)
  • 6720425G15Rik Protéine
  • AW208651 Protéine
  • AW489976 Protéine
  • E230011J22 Protéine
  • mKIAA0602 Protéine
  • PACS-2 Protéine
  • Pacs1l Protéine

Protein level used designations for PACS2

PACS1-like protein , PACS-2

GENE ID SPECIES
23241 Homo sapiens
217893 Mus musculus
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