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SERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. De plus, nous expédions SERPINB9 Protéines (8) et SERPINB9 Kits (7) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 113 products:
Human Monoclonal SERPINB9 Primary Antibody pour FACS - ABIN2476137
Hall, Keane: Proceedings: Dopaminergic and cholinergic interactions in the caudate nucleus in relation to the induction of sleep in the cat. dans British journal of pharmacology 1975
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Human Monoclonal SERPINB9 Primary Antibody pour IHC (fro), FACS - ABIN2476136
Hirst, Buzza, Sutton, Trapani, Loveland, Bird: Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction. dans Molecular human reproduction 2001
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Mouse (Murine) Polyclonal SERPINB9 Primary Antibody pour FACS, WB - ABIN2192172
Zhang, Byrne, Liu, Wang, Oxenius, Ashton-Rickardt: Differential survival of cytotoxic T cells and memory cell precursors. dans Journal of immunology (Baltimore, Md. : 1950) 2007
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Human Polyclonal SERPINB9 Primary Antibody pour ELISA, WB - ABIN188847
Jiang, Ellison, Alarid, Shapiro: Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells. dans Oncogene 2007
Data suggest that reactive oxygen species (ROS (Montrer ROS1 Anticorps)) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B (Montrer Gzmb Anticorps)) into the cytosol and for inactivation of serpin B9.
the negative regulation of DC priming of CD8 (Montrer CD8A Anticorps) T lymphocyte immunity by CTL killing is mitigated by the physiological inhibition of GrB by Spi6.
SPI-CI (Montrer OVA Anticorps) is a novel immune escape molecule that acts in concert with SPI (Montrer CHGA Anticorps)-6 to prevent cytotoxic lymphocyte-mediated killing of tumor cells.
Estrogen induction of PI-9 may reduce the ability of cytolytic lymphocytes-mediated immune surveillance to destroy newly transformed cells
In mCAP3 (Montrer ST14 Anticorps), an intact catalytic triad was necessary for activation of ENaC (Montrer SCNN1A Anticorps) but not for intramolecular cleavage of the protease.
protects hepatocytes against excessively vigorous granzyme B (Montrer Gzmb Anticorps)-dependent killing but may also delay immune clearance of virally infected hepatocytes
deficiency in a weak intracellular inhibitor of neutrophil elastase (Montrer ELANE Anticorps) results in an acute inflammatory response that protects from P. aeruginosa but does not cause lung disease
SPI (Montrer CHGA Anticorps)-6 is selectively up-regulated in hepatocytes in response to infiltration of the liver by NK cells that express perforin (Montrer PRF1 Anticorps) and enzymatically active granzyme B (Montrer Gzmb Anticorps).
Increased SPI (Montrer CHGA Anticorps)-6 expression is not sufficient to confer lipopolysaccharide-treated dendritic cells with resistance to direct killing in vivo.
Treatment with estrogens further increased PI-9 level while decreased that of ERalpha66 isoform thus excluding the involvement of this receptor isoform in the event. Moreover, our studies also provided evidence that tertiary tumorspheres express elevated levels of CXCR4 (Montrer CXCR4 Anticorps) and phospho-p38 (Montrer CRK Anticorps), suggesting that the high PI-9 content might be ascribed to the activation of the proliferative CXCR4 (Montrer CXCR4 Anticorps)/phospho-p38 (Montrer CRK Anticorps) axis.
We filtered four OSCC genes including SERPINB9, SERPINE2 (Montrer SERPINE2 Anticorps), GAK (Montrer GAK Anticorps), and HSP90B1 (Montrer HSP90B1 Anticorps) through the gene global prioritization score (P < 0.005).
Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1 (Montrer SERPINB1 Anticorps), SERPINB4 (Montrer SERPINB4 Anticorps) and SERPINB9 for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.
Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC (Montrer HLAE Anticorps)-I and CD1d (Montrer CD1D Anticorps) expression. Intriguingly, expression of SERPINB9, SERPINB1 (Montrer SERPINB1 Anticorps), and SERPINB4 (Montrer SERPINB4 Anticorps) is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors
Increased intracellular PI-9 activity in mononuclear phagocytes from HIV-infected patients contributes to successful intracellular infection by virulent Mycobacterium tuberculosis.
Suppression of granzyme B (Montrer Gzmb Anticorps) initiated apoptosis in protease inhibitor-9-expressing leukemia cells.
SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3 (Montrer TLR3 Anticorps), MDA5 (Montrer IFIH1 Anticorps) and RIG-I (Montrer DDX58 Anticorps) during subclinical rejection.
lung cancer cells utilise their increased PI-9 expression to protect from granzyme B (Montrer Gzmb Anticorps)-mediated cytotoxicity as an immune evasion mechanism
Inhibition of Granzyme B (Montrer Gzmb Anticorps) by PI-9 protects prostate cancer cells from apoptosis.
This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.
serine (or cysteine) peptidase inhibitor, clade B, member 9
, serpin B9
, serpin peptidase inhibitor, clade B (ovalbumin), member 9
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9
, Cytoplasmic antiproteinase 3
, serpin B9-like
, serine (or cysteine) proteinase inhibitor, clade B, member 9
, serine protease inhibitor 6
, cytoplasmic antiproteinase 3
, peptidase inhibitor 9
, protease inhibitor 9 (ovalbumin type)
, serpin peptidase inhibitor, clade B, member 9