CD79a anticorps (FITC)
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- Antigène Voir toutes CD79a (CD79A) Anticorps
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD79a est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS)
- Specificité
- This antibody reacts with CD79a positive cells by flow cytometry. This clone has been reported to be useful in distinguishing B-CLL from mantle cell lymphoma in flow cytometric assays.
- Immunogène
- IgM complex isolated from Daudi cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
- Clone
- ZL7-4
- Isotype
- IgG1
- Top Product
- Discover our top product CD79A Anticorps primaire
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- Indications d'application
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Flow Cytometry: Use 10 μL of neat antibody to label 1x10^6 cells in 100 μL. We recommend incubation times of at least 30 minutes with this antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Autre désignation
- CD79a (CD79A Produits)
- Synonymes
- anticorps CD79A, anticorps Ig-alpha, anticorps Iga, anticorps Igalpha, anticorps Ly-54, anticorps Ly54, anticorps mb-1, anticorps IGA, anticorps MB-1, anticorps IG-alpha, anticorps CD79a molecule, anticorps CD79A antigen (immunoglobulin-associated alpha), anticorps Cd79a molecule-like, anticorps CD79A, anticorps Cd79a, anticorps Cd79al
- Sujet
- A disulfide-linked heterodimer, consisting of CD79a / mb1 and CD79b / B29 polypeptides, is non-covalently associated with membrane bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. The CD79a/b heterodimer interacts with at least one tyrosine kinase (Lyn). Induction of tyrosine kinase activity after antigen binding causes phosphorylation of the CD79a/b dimer, and also of other molecules, thereby initiating intracellular signaling.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
- ID gène
- 973
- NCBI Accession
- NP_001774
- UniProt
- P11912
- Pathways
- BCR Signaling
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