CD97 anticorps

N° du produit ABIN119250

Détail du produit anti-CD97 anticorps

Antigène: CD97

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD97 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificité: The antibody recognizes an unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein-A affinity chromatography

Pureté: > 95 % pure (by SDS-PAGE)

Immunogène: PHA-activated blood cells

Clone: MEM-180

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: 1/200 - 1/400, use 10 μL of the suggested working dilution to label 10^6 cells. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD97

Antigène: CD97

Autre désignation: CD97 (CD97 Produits)

Synonymes: anticorps AA409984, anticorps TM7LN1, anticorps adhesion G protein-coupled receptor E5, anticorps Adgre5, anticorps ADGRE5

Sujet: CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.Synonyms: Leukocyte antigen CD97

ID gène: 976

NCBI Accession: NP_001020331

UniProt: P48960