ERBB4 anticorps (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian)) (pTyr1056) (HRP)

Details for Product anti-ERBB4 Antibody No. ABIN1712584, Fournisseur: Connectez-vous pour afficher
Antigène
  • erbb4
  • si:ch211-227n20.1
  • Her4
  • c-erbB-4
  • HER4
  • p180erbB4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4a (avian)
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
  • receptor tyrosine-protein kinase ErbB-4
  • v-erb-a erythroblastic leukemia viral oncogene homolog 4
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 4
  • ERBB4
  • erbb4a
  • erbb4
  • Tsp_13582
  • Erbb4
Épitope
pTyr1056
55
37
37
33
24
21
21
19
17
15
14
11
7
6
6
6
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
403
178
144
12
9
6
6
6
5
3
3
3
2
2
2
1
1
Hôte
Lapin
301
106
2
Clonalité
Polyclonal
Conjugué
Cet anticorp ERBB4 est conjugé à/à la HRP
21
18
16
16
12
10
10
10
8
8
8
5
5
5
5
5
5
5
5
3
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
212
144
126
91
70
68
28
23
15
6
5
3
2
1
1
Options
Fournisseur
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Supplier Product No.
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Immunogène KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1056 [PA(p-Y)TP]
Isotype IgG
Purification Purified by Protein A.
Autre désignation Her4 (ERBB4 Antibody Extrait)
Sujet

This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].

Synonyms: ErbB 4 phospho Y1056, p-ErbB 4 phospho Y1056, ErbB4, HER 4, HER4, Avian erythroblastic leukemia viral oncogene homolog 4, Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4, MGC138404, P180erbB4, Receptor protein tyrosine kinase erbB 4 precursor, Receptor tyrosine protein kinase erbB 4,Tyrosine kinase type cell surface receptor HER4, v erb a avian erythroblastic leukemia viral oncogene homolog like 4, v erb a erythroblastic leukemia viral oncogene homolog 4, Verba avian erythroblastic leukemia viral oncogene homolog like 4, Verba erythroblastic leukemia viral oncogene homolog 4, VERBB2.

ID gène 2066
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months
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