RPSA anticorps (Ribosomal Protein SA)

Details for Product anti-RPSA Antibody No. ABIN1713335, Fournisseur: Connectez-vous pour afficher
Antigène
  • 37LRP
  • 67LR
  • LBP/p40
  • LRP/LR
  • LamR
  • rpsa
  • LamR1
  • RPSA
  • LAMBR
  • LAMR1
  • LBP
  • LRP
  • NEM/1CHD4
  • SA
  • lamR
  • p40
  • 67kDa
  • 67lr
  • AL022858
  • Lamr
  • Lamr1
  • Lamrl1
  • MLR
  • P40
  • P40-3
  • P40-8
  • lamr1
  • zgc:55831
  • zgc:77824
  • DMRT1
  • 40S ribosomal protein SA
  • 67kD laminin receptor
  • laminin receptor 1
  • ribosomal protein SA
  • rssa
  • rpsa
  • LOC100125628
  • RPSA
  • Rpsa
Alternatives
anti-Rat (Rattus) RPSA anticorps pour ELISA
Reactivité
Humain, Rat (Rattus)
73
27
20
6
6
5
4
4
4
4
4
3
3
2
2
2
Hôte
Souris
50
24
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp RPSA est non-conjugé
3
3
3
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
55
33
20
19
14
8
4
2
2
1
1
1
1
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from middle of human LAMR1
Clone 5D4
Isotype IgG
Purification Purified by Protein G.
Autre désignation LAMR1 (RPSA Antibody Extrait)
Sujet

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Synonyms: 37LRP, P37- kDa laminin receptor precursor, MGr1-Ag, laminin receptor 1, 67kD, ribosomal protein SA, 34/67 kDa laminin receptor, 40S ribosomal protein SA, 67LR, Colon carcinoma laminin-binding protein, LAMBR, Laminin Receptor 1, LAMR 1, LAMR1, LRP, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, p40, Ribosomal Protein SA, RPSA, 67kD laminin receptor.

ID gène 3921
Pathways Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Indications d'application WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Produit citée dans: Wang, Yu, Guan, Liu, Qiao: "67-kDa Laminin receptor contributes to hypoxia-induced migration and invasion of trophoblast-like cells by mediating matrix metalloproteinase-9." dans: Clinical and experimental pharmacology & physiology, Vol. 42, Issue 5, pp. 549-58, 2015 (PubMed).