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RPSA/Laminin Receptor Produits

(Ribosomal Protein SA (RPSA))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories RPSA/Laminin Receptor en vedette

RPSA/Laminin Receptor Anticorps

High quality antibodies with extensive validation data.

RPSA/Laminin Receptor Kits ELISA

Reliable ELISA kits for a wide range of species.

RPSA/Laminin Receptor Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

RPSA/Laminin Receptor recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, FACS, StM
Validations
  • (10)
N° du produit ABIN6939957
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
N° du produit ABIN2854873
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (4)
N° du produit ABIN6147247
Quantité 100 μL
Fiche technique Fiche technique

RPSA/Laminin Receptor recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6959194
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method
Validations
N° du produit ABIN1773464
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1774688
Quantité 96 tests
Fiche technique Fiche technique

RPSA/Laminin Receptor recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318864
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1318866
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN3132971
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits RPSA/Laminin Receptor

Umbaugh, Diaz-Quiñones, Neto, Shearer, Figueiredo: "A dock derived compound against laminin receptor (37 LR) exhibits anti-cancer properties in a prostate cancer cell line model." dans: Oncotarget, Vol. 9, Issue 5, pp. 5958-5978, (2018) (PubMed).

Wang, Yu, Guan, Liu, Qiao: "67-kDa Laminin receptor contributes to hypoxia-induced migration and invasion of trophoblast-like cells by mediating matrix metalloproteinase-9." dans: Clinical and experimental pharmacology & physiology, Vol. 42, Issue 5, pp. 549-58, (2015) (PubMed).

Santamarina, Oliveira, Silva, Carnier, Mennitti, Santana, de Souza, Ribeiro, Oller do Nascimento, Lira, Oyama: "Green Tea Extract Rich in Epigallocatechin-3-Gallate Prevents Fatty Liver by AMPK Activation via LKB1 in Mice Fed a High-Fat Diet." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0141227, (2015) (PubMed).

Song, Choi, Cho, Sung, Song, Kim, Bae, Lee, Kim: "Expression of 67-kDa laminin receptor was associated with tumor progression and poor prognosis in epithelial ovarian cancer." dans: Gynecologic oncology, Vol. 125, Issue 2, pp. 427-32, (2012) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." dans: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Starborg, Gell, Brundell, Höög: "The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression." dans: Journal of cell science, Vol. 109 ( Pt 1), Issue 12, pp. 143-53, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à RPSA/Laminin Receptor

40S ribosomal protein SA (rssa), 67kD laminin receptor (rpsa), ribosomal protein SA (RPSA), ribosomal protein SA (Rpsa), ribosomal protein SA (rpsa), 40S ribosomal protein SA (LOC100144340), 37LRP, 67kDa, 67LR, 67lr, AL022858, DMRT1, LAMBR, LamR, lamR, Lamr, LamR1, LAMR1, Lamr1, lamr1, Lamrl1, LBP, LBP/p40, LRP, LRP/LR, MLR, NEM/1CHD4, p40, P40, P40-3, P40-8, rpsa, RPSA, SA, zgc:55831, zgc:77824

Protein level used designations for RPSA/Laminin Receptor

  • 37 kDa laminin receptor
  • 37/67 kDa laminin receptor
  • 67 kDa laminin receptor
  • Laminin receptor 1
  • Laminin-binding protein precursor p40
  • ribosomal protein SA
  • 40S ribosomal protein SA
  • laminin-binding protein precursor p40
  • 37LRP
  • 67LR
  • LBP/p40
  • LRP/LR
  • lamR
  • colon carcinoma laminin-binding protein
  • laminin receptor 1 (67kD, ribosomal protein SA)
  • multidrug resistance-associated protein MGr1-Ag
  • 37 kDa oncofetal antigen
  • OFA/iLRP
  • P40-3, functional
  • P40-8, functional
  • laminin receptor 1 (ribosomal protein SA)
  • 37kD Laminin receptor
  • laminin receptor 1
  • laminin receptor 1 (ribosomal protein SA, 67 kDA)
  • ribosomal protein SA pseudogene
  • laminin receptor
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