TRAF1 anticorps (Middle Region)

N° du produit ABIN2792210

Détail du produit anti-TRAF1 anticorps

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Épitope: Middle Region

Reactivité: Humain, Souris, Boeuf (Vache), Lapin, Chien, Poisson zèbre (Danio rerio), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF1 est non-conjugé

Application: Western Blotting (WB)

Séquence: DAFRPDLSSA SFQRPQSETN VASGCPLFFP LSKLQSPKHA YVKDDTMFLK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 84%

Attributs du produit: This is a rabbit polyclonal antibody against TRAF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRAF1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 416 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRAF1

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Autre désignation: TRAF1 (TRAF1 Produits)

Synonymes: anticorps CG3048, anticorps DTRAF, anticorps DTRAF1, anticorps Dmel\\CG3048, anticorps TRAF, anticorps TRAF1, anticorps Traf1, anticorps dTRAF, anticorps dTRAF1, anticorps dTraf1, anticorps dtraf1, anticorps traf1, anticorps traf4, anticorps DKFZp469G032, anticorps EBI6, anticorps MGC:10353, anticorps 4732496E14Rik, anticorps TNF receptor associated factor 1, anticorps TNF-receptor-associated factor 4, anticorps TNF receptor-associated factor 1, anticorps TRAF1, anticorps Traf4, anticorps Traf1, anticorps traf1

Sujet: This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EBI6, MGC:10353
Protein Interaction Partner: ZNF662, KLHL38, TRIM42, RTP5, SSC5D, MORN3, POM121L4P, OLIG3, CCDC116, ZNF564, SLC25A48, ALS2CR11, LOC149950, ZNF417, TMC8, ZNF572, RBM45, C1orf216, ZNF440, TBC1D16, HAUS1, SYCE1, ZNF502, C5orf30, CCDC120, FBF1, ZNF587, BEX2, LCOR, FAM161A, PLEKHN1, RASSF
Protein Size: 416

Poids moléculaire: 46 kDa

ID gène: 7185

NCBI Accession: NM_005658, NP_005649

UniProt: Q13077

Pathways: Signalisation NF-kappaB, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization