ATG3 anticorps
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- Antigène Voir toutes ATG3 Anticorps
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
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Reactivité
- Humain
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Hôte
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Mouton
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ATG3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Specific for ATG3.
- Réactivité croisée
- Humain, Souris, Rat
- Réactivité croisée (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogène
- A synthetic peptide from human ATG3 conjugated to an immunogenic carrier protein has been used as the antigen. The antigen is homologous in rat and mouse.
- Isotype
- IgG
- Top Product
- Discover our top product ATG3 Anticorps primaire
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- Indications d'application
- IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- Conseil sur la manipulation
- Avoid freeze and thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ATG3 (ATG3 Autophagy Related 3 (ATG3))
- Autre désignation
- ATG3 (ATG3 Produits)
- Synonymes
- anticorps atg3, anticorps im:6910145, anticorps wu:fb15g12, anticorps zgc:64156, anticorps APG3, anticorps APG3-LIKE, anticorps APG3L, anticorps PC3-96, anticorps 2610016C12Rik, anticorps Apg3l, anticorps Atg3l, anticorps PIG-1, anticorps Pig1, anticorps ATATG3, anticorps K11J9.1, anticorps K11J9_1, anticorps autophagy related 3, anticorps autophagy 3 (APG3), anticorps similar to S. cerevisiae ATG3 (YNR007C) part of ubiquitin-like system that mediates Atg8-phosphatidylethanolamine conjugation required for protein-vacuolar targeting and autophagy, anticorps atg3, anticorps ATG3, anticorps Atg3
- Sujet
- Autophagy is a process of bulk degradation of cytoplasmic components by the lysosome or vacuole. Human ATG3 displays the same enzymatic characteristics in vitro as yeast Apg3, a protein-conjugating enzyme essential for autophagy. FUNCTION: GABARAPL1 (GABARAPL2 or GABARAP or MAP1LC3)-modifier protein conjugating enzyme involved in its E2-like covalent binding to PE. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3 (E2-like enzyme). Preferred substrate is MAP1LC3A. Formation of the GABARAPL1-PE conjugate is essential for autophagy. SUBCELLULAR LOCATION: Cytoplasm TISSUE SPECIFICITY: Widely expressed, with a highest expression in heart, skeletal muscle, kidney, liver and placenta.,Mammalian Autophagy,APG3, APG3L, APG3-like
- UniProt
- Q9NT62
- Pathways
- Autophagy
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