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NEDD8 anticorps (N-Term)
NEDD8
Reactivité: Humain
WB, IHC (p)
Hôte: Lapin
Polyclonal
RB0639
unconjugated
Détail du produit anti-NEDD8 anticorps
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Antigène
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NEDD8
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
Épitope
Tous les épitopes à travers NEDD8 Anticorps.
AA 1-32, N-Term
Reactivité
Toutes les réactivités sur NEDD8 Anticorps
Humain
Hôte
Toutes les hôtes sur NEDD8 Anticorps
Lapin
Clonalité
Toutes les clonalités sur NEDD8 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NEDD8 Anticorps
Cet anticorp NEDD8 est non-conjugé
Application
Tous les applications à travers NEDD8 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
B, M, Rb, Rat
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This NEDD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human NEDD8.
Clone
RB0639
Isotype
Ig Fraction
Top Product
Discover our top product NEDD8 Anticorps primaire
Alternatives
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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (N-Term) antibody
NEDD8
Reactivité: Humain, Souris, Rat, Singe, Boeuf (Vache), Xenopus laevis
WB, IHC, IHC (p), IF, FACS, IP
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
(cache)
Indications d'application
WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Détails sur NEDD8
(cache)
Antigène
NEDD8
(Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
Autre désignation
NEDD8 (NEDD8 Produits )
Synonymes
anticorps NEDD-8, anticorps Rub1, anticorps CG10679, anticorps Dmel\\CG10679, anticorps NEDD8, anticorps dNEDD8, anticorps nedd8, anticorps ubiquitin, anticorps si:zc14a17.5, anticorps GB17785, anticorps DDBDRAFT_0218116, anticorps DDBDRAFT_0238041, anticorps DDB_0218116, anticorps DDB_0238041, anticorps nedd8.S, anticorps neural precursor cell expressed, developmentally down-regulated 8, anticorps neural precursor cell expressed, developmentally down-regulated gene 8, anticorps CG10679 gene product from transcript CG10679-RB, anticorps Nedd8, anticorps ubiquitin-like protein Nedd8, anticorps neural precursor cell expressed, developmentally down-regulated 8 L homeolog, anticorps NEDD8, anticorps Nedd8, anticorps nedd8, anticorps nedd8.L
Sujet
NEDD8 is a ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Poids moléculaire
9072
ID gène
4738
NCBI Accession
NP_006147
UniProt
Q15843
Pathways
Ubiquitin Proteasome Pathway
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