FGFR3 anticorps (C-Term)

N° du produit ABIN391969

Détail du produit anti-FGFR3 anticorps

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Épitope: AA 776-806, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This FGFR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 776-806 amino acids from the C-terminal region of human FGFR3.

Clone: RB01572

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur FGFR3

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Autre désignation: FGFR3 (FGFR3 Produits)

Synonymes: anticorps FGFR3, anticorps LOC100034114, anticorps ACH, anticorps CD333, anticorps CEK2, anticorps HSFGFR3EX, anticorps JTK4, anticorps FR3, anticorps Fgfr-3, anticorps Flg-2, anticorps HBGFR, anticorps Mfr3, anticorps sam3, anticorps fc27h01, anticorps wu:fc27h01, anticorps fibroblast growth factor receptor 3, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog, anticorps FGFR3, anticorps fgfr3.S, anticorps Fgfr3, anticorps fgfr3

Sujet: FGFR3 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.

Poids moléculaire: 87710

ID gène: 2261

NCBI Accession: NP_000133, NP_001156685, NP_075254

UniProt: P22607

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding