Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Presenilin 2 anticorps (N-Term)

PSEN2 Reactivité: Humain WB, IHC (p), IHC (f) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN966891
  • Antigène Voir toutes Presenilin 2 (PSEN2) Anticorps
    Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
    Épitope
    • 15
    • 9
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 59
    • 41
    • 32
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 49
    • 4
    • 3
    • 2
    • 1
    Lapin
    Clonalité
    • 54
    • 5
    Polyclonal
    Conjugué
    • 35
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Presenilin 2 est non-conjugé
    Application
    • 48
    • 19
    • 13
    • 12
    • 11
    • 10
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
     Réactivité croisée
    Souris, Rat (Rattus)
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Presenilin-2 ( PSEN2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.
    Immunogène
    A synthetic peptide corresponding to a sequence at the N-terminal of human Presenilin-2, different from the related mouse and rat sequences by two amino acids.< br/>Immunogen was affinity purified.
    Isotype
    IgG
    Top Product
    Discover our top product PSEN2 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide, Thimerosal (Merthiolate)
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Hoek, Schlegel, Eichhoff, Widmer, Praetorius, Einarsson, Valgeirsdottir, Bergsteinsdottir, Schepsky, Dummer, Steingrimsson: "Novel MITF targets identified using a two-step DNA microarray strategy." dans: Pigment cell & melanoma research, Vol. 21, Issue 6, pp. 665-76, (2008) (PubMed).

    Kaplan, Renbaum, Vreman, Wong, Levy-Lahad, Hammerman, Stevenson: "(TA)n UGT 1A1 promoter polymorphism: a crucial factor in the pathophysiology of jaundice in G-6-PD deficient neonates." dans: Pediatric research, Vol. 61, Issue 6, pp. 727-31, (2007) (PubMed).

    Levy-Lahad, Wijsman, Nemens, Anderson, Goddard, Weber, Bird, Schellenberg: "A familial Alzheimer's disease locus on chromosome 1." dans: Science (New York, N.Y.), Vol. 269, Issue 5226, pp. 970-3, (1995) (PubMed).

  • Antigène
    Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
    Autre désignation
    Presenilin-2(PS-2) (PSEN2 Produits)
    Synonymes
    anticorps AD3L, anticorps AD4, anticorps CMD1V, anticorps PS2, anticorps STM2, anticorps ALG-3, anticorps Ad4h, anticorps Alg3, anticorps PS-2, anticorps Psnl2, anticorps pre2, anticorps zf-PS2, anticorps PSNL2, anticorps PSEN2, anticorps ad4, anticorps ps2, anticorps ad3l, anticorps stm2, anticorps Ps2, anticorps presenilin 2, anticorps presenilin 2 S homeolog, anticorps presenilin 2 (Alzheimer disease 4), anticorps trefoil factor 1, anticorps PSEN2, anticorps Psen2, anticorps psen2, anticorps psen2.S, anticorps Tff1
    Sujet
    Presenilin-2 is a protein that in humans is encoded by the PSEN2 gene. [1]Kovacs et al. (1996) demonstrated that the expression patterns of PS1 and PS2 in the brain are extremely similar to each other and that messages for both are primarily detectable in neuronal populations. Immunochemical analyses indicated that PS1 and PS2 are similar in size and localize to similar intracellular compartments (endoplasmic reticulum and Golgi complex). Li et al. (1997) demonstrated that wildtype PS1 and PS2 are localized to the nuclear membrane, its associated interphase kinetochores, and the centrosomes. In melanocytic cells PSEN2 gene expression may be regulated by MITF. [2]
    Pathways
    Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Vous êtes ici:
Support technique