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KDM3A anticorps

KDM3A Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 1-00E-12 unconjugated
N° du produit ABIN969228
  • Antigène Voir toutes KDM3A Anticorps
    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
    Reactivité
    • 46
    • 10
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 15
    Souris
    Clonalité
    • 31
    • 15
    Monoclonal
    Conjugué
    • 31
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KDM3A est non-conjugé
    Application
    • 37
    • 23
    • 21
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human KDM3A expressed in E. coli.
    Clone
    1-00E-12
    Isotype
    IgG1
    Top Product
    Discover our top product KDM3A Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." dans: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).

    Nagase, Ishikawa, Suyama, Kikuno, Miyajima, Tanaka, Kotani, Nomura, Ohara: "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." dans: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 5, pp. 277-86, (1999) (PubMed).

  • Antigène
    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
    Autre désignation
    KDM3A (KDM3A Produits)
    Synonymes
    anticorps JHDM2A, anticorps JHMD2A, anticorps JMJD1, anticorps JMJD1A, anticorps TSGA, anticorps tsga, anticorps jmjd1, anticorps jhdm2a, anticorps jhmd2a, anticorps jmjd1a, anticorps 1700105C21Rik, anticorps C230043E16Rik, anticorps JHDM2a, anticorps Jmjd1, anticorps Jmjd1a, anticorps KDM2A, anticorps TGSA, anticorps Tsga, anticorps mKIAA0742, anticorps KDM3A, anticorps kdm3a, anticorps lysine demethylase 3A, anticorps lysine (K)-specific demethylase 3A, anticorps lysine-specific demethylase 3A, anticorps lysine (K)-specific demethylase 3A S homeolog, anticorps KDM3A, anticorps kdm3a, anticorps Kdm3a, anticorps LOC100453519, anticorps kdm3a.S
    Sujet

    Description: This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and α-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.

    Aliases: TSGA, JMJD1, JHDM2A, JHMD2A, JMJD1A, KIAA0742, DKFZp686A24246, DKFZp686P07111, KDM3A

    Poids moléculaire
    147 kDa
    ID gène
    55818
    HGNC
    55818
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, L'effet Warburg
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