ERBB4 anticorps (pTyr1242)
Aperçu rapide pour ERBB4 anticorps (pTyr1242) (ABIN126796)
Antigène
Voir toutes ERBB4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pTyr1242
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Specificité
- This antibody specifically recognizes erbB4 phosphorylated on Tyr 1242 at 180 kDa.
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Attributs du produit
- Synonyms: p180erbB4, c-ErbB-4, HER-4, Receptor tyrosine-protein kinase erbB-4, Proto-oncogene-likeprotein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4
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Purification
- Size exclusion chromatography
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Ingrédients
- incl. positive Control
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Immunogène
- Phosphopeptide conjugated to hemocyanin
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Isotype
- IgG
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anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 29-278) antibody
ERBB4 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1284) antibodyERBB4 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (C-Term) antibodyERBB4 Reactivité: Humain, Souris, Rat WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1159-1308) antibodyERBB4 Reactivité: Humain IHC, ELISA, FACS Hôte: Souris Monoclonal 5G6B4 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1116-1269) antibodyERBB4 Reactivité: Humain IHC Hôte: Souris Monoclonal ERBB4-2581 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1162) antibodyERBB4 Reactivité: Humain WB, IF, IHC (p) Hôte: Lapin Polyclonal RB5687 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1162) antibodyERBB4 Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1116-1269) antibodyERBB4 Reactivité: Humain, Souris IF, FACS Hôte: Souris Monoclonal HFR-1 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1159-1308) antibodyERBB4 Reactivité: Humain ELISA, FACS, ICC Hôte: Souris Monoclonal 4E7G5 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1188) antibodyERBB4 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB6051 unconjugated
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Indications d'application
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Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Protocole
- Positive control: Cell lysate from EGF-treated MDA-MB 468 cellsFormulationLyophilized cell lysate from MDA-MB-468 cells. Serum starved cells were treated for 15 min with EGF.
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS/0.09 % Na-Azide/PEG and Sucrose/50 % Glycerol
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
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Store the antibody (in aliquot) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
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Autre désignation
- ERBB4 / HER4
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Sujet
- ErbB4/Her4 is a member of the receptor tyrosine kinase subfamily that includes EGFR, erbB2/her2, and erbB3/Her3. erbB4 is a receptor for Neuregulin 1 (NRG1) and regulates cell proliferation and differentiation. Tyr 1242 is a potential SHC binding site which leads to MAPK signalling pathway.Synonyms: HER-4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell surface receptor HER4, c-ErbB-4, p180erbB4
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ID gène
- 2066
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UniProt
- Q15303
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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