Aperçu des produits pour anti-CYLD (CYLD) Anticorps

Full name:
anti-Cylindromatosis (Turban Tumor Syndrome) Anticorps (CYLD)
Chez www.anticorps-enligne.fr sont 79 Cylindromatosis (Turban Tumor Syndrome) (CYLD) Anticorps de 18 de différents fournisseurs disponibles. De plus, nous expédions CYLD Kits (9) et CYLD Protéines (8) et beaucoup plus de produits pour cette protéine. Un total de 99 CYLD produits sont actuellement listés.
Synonymes:
2010013M14Rik, 2900009M21Rik, BRSS, C130039D01Rik, CDMT, cyld, CYLD1, CYLDI, EAC, LRRGT00003, MFT, MFT1, mKIAA0849, Rp1, Rp1h, SBS, TEM, USPL2

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anti-CYLD Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal CYLD Primary Antibody pour ELISA, WB - ABIN188848 : Massoumi, Chmielarska, Hennecke, Pfeifer, Fässler: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. dans Cell 2006 (PubMed)

  2. Human Polyclonal CYLD Primary Antibody pour ICC, IF - ABIN252428 : Moranta, Regueiro, March, Llobet, Margareto, Larrarte, Larrate, Garmendia, Bengoechea: Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells. dans Infection and immunity 2010 (PubMed)

Plus d’anticorps contre CYLD partenaires d’interaction

Zebrafish Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. The crystal structures representing the catalytic states of zebrafish CYLD for Met1 (Montrer DNMT1 Anticorps)- and Lys63-linked Ub chains and two distinct precatalytic states for Met1 (Montrer DNMT1 Anticorps)-linked chains are presented.

Mouse (Murine) Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. TLR4 (Montrer TLR4 Anticorps) activates CASPASE-8 (Montrer CASP8 Anticorps) to cleave and remove the deubiquitinase cylindromatosis (CYLD) in a TRIF (Montrer RNF138 Anticorps)- and RIPK1 (Montrer RIPK1 Anticorps)-dependent manner to disable necroptosis in macrophages.

  2. CYLD contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 (Montrer NOX4 Anticorps) and may play a role in vascular remodeling.

  3. this study shows that by polarization of the T cell cytokine response, CYLD can favor the development of allergic airway disease

  4. Our findings underscore a critical tumor-suppressing role for functional intestinal epithelial CYLD in colitis-associated carcinogenesis

  5. Deubiquitinase CYLD negatively regulates MyD88 (Montrer MYD88 Anticorps)-mediated signaling by directly interacting with MyD88 (Montrer MYD88 Anticorps) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (Montrer MYD88 Anticorps) at lysine 231.

  6. CYLD interrupts the ERK (Montrer EPHB2 Anticorps)- and p38 (Montrer CRK Anticorps)-/AP-1 (Montrer JUN Anticorps) and c-Myc (Montrer MYC Anticorps) pathways to suppress Nrf2 (Montrer NFE2L2 Anticorps)-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.

  7. Our data demonstrate that inefficient negative selection in the thymus of CYLD(ex7/8) mice result from a defect in mTEC maturation.

  8. The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.

  9. Data show that the in utero death of NF-NF (Montrer NFASC Anticorps)-kappaB (Montrer NFKB1 Anticorps) essential modulator (NEMO (Montrer IKBKG Anticorps)) and cylindromatosis protein double mutant mice is mediated by TNF (Montrer TNF Anticorps) receptor 1 (TNFR1 (Montrer TNFRSF1A Anticorps)) signaling and can be rescued by TNFR1 (Montrer TNFRSF1A Anticorps) deficiency.

  10. CYLD is a central regulator of apoptotic cell death in murine hepatocytes by controlling NF-kappaB (Montrer NFKB1 Anticorps) dependent anti-apoptotic signaling.

Human Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. The data reveal SPATA2 (Montrer SPATA2 Anticorps) as a high-affinity binding partner of CYLD and HOIP (Montrer RNF31 Anticorps), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (Montrer NFKB1 Anticorps) signaling.

  2. The current investigations identified a subset of HPV-positive HNSCCs with mutations in the genes TRAF3 (Montrer TRAF3 Anticorps) (tumor necrosis factor (Montrer TNF Anticorps) receptor-associated factor 3) and CYLD (cylindromatosis lysine 63 deubiquitinase). Defects in TRAF3 (Montrer TRAF3 Anticorps) and CYLD correlated with the activation of transcriptional factor nuclear factor kappaB, episomal HPV status of tumors, and improved patient survival.

  3. The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes.

  4. STAT3 (Montrer STAT3 Anticorps) and miR (Montrer MLXIP Anticorps)-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway.

  5. CYLD Promotes TNF-alpha (Montrer TNF Anticorps)-Induced Cell Necrosis Mediated by RIP-1 (Montrer UQCRFS1 Anticorps) in Human Lung Cancer Cells

  6. Low CYLD expression is associated with hepatocellular carcinoma.

  7. miR20a directly repressed the expression of CYLD, leading to activation of the NFkappaB (Montrer NFKB1 Anticorps) pathway and the downstream targets, livin (Montrer BIRC7 Anticorps) and survivin (Montrer BIRC5 Anticorps), which potentially induced GC chemoresistance.

  8. Data show that cylindromatosis (CYLD) overexpression and livin (Montrer BIRC7 Anticorps) knockdown might improve gemcitabine chemosensitivity by decreasing autophagy and increasing apoptosis in bladder cancer (BCa (Montrer BLNK Anticorps)) cells.

  9. aberrantly expressed miR (Montrer MLXIP Anticorps)-130b may regulate cell apoptosis and proliferation of human gastric cancer cells via CYLD, which appears to be a promising therapeutic target for gastric cancer

  10. These results demonstrate the involvement of histone deacetylases in the down regulation of Cyld expression in hepatocellular carcinoma cells.

CYLD profil antigène

Antigen Summary

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CYLD

  • cylindromatosis (turban tumor syndrome) (CYLD) anticorps
  • cylindromatosis (turban tumor syndrome), a (cylda) anticorps
  • ubiquitin carboxyl-terminal hydrolase CYLD (LOC100362727) anticorps
  • cylindromatosis (turban tumor syndrome) (Cyld) anticorps
  • 2010013M14Rik anticorps
  • 2900009M21Rik anticorps
  • BRSS anticorps
  • C130039D01Rik anticorps
  • CDMT anticorps
  • cyld anticorps
  • CYLD1 anticorps
  • CYLDI anticorps
  • EAC anticorps
  • LRRGT00003 anticorps
  • MFT anticorps
  • MFT1 anticorps
  • mKIAA0849 anticorps
  • Rp1 anticorps
  • Rp1h anticorps
  • SBS anticorps
  • TEM anticorps
  • USPL2 anticorps

Protein level used designations for CYLD

cylindromatosis (turban tumor syndrome) , probable ubiquitin carboxyl-terminal hydrolase CYLD-like , ubiquitin carboxyl-terminal hydrolase CYLD , deubiquitinating enzyme CYLD , ubiquitin thioesterase CYLD , ubiquitin thiolesterase CYLD , ubiquitin-specific-processing protease CYLD , probable ubiquitin carboxyl-terminal hydrolase CYLD , retinitis pigmentosa 1 homolog , ubiquitin specific peptidase like 2

GENE ID SPECIES
100050308 Equus caballus
556823 Danio rerio
100467467 Ailuropoda melanoleuca
100547998 Meleagris gallopavo
100362727 Rattus norvegicus
74256 Mus musculus
312937 Rattus norvegicus
1540 Homo sapiens
611649 Canis lupus familiaris
536421 Bos taurus
415725 Gallus gallus
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