Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Human CYLD Anticorps:
anti-Mouse (Murine) CYLD Anticorps:
anti-Rat (Rattus) CYLD Anticorps:
Vous arrivez à notre recherche pré-filtrée.
Mouse (Murine) Polyclonal CYLD Primary Antibody pour ELISA, WB - ABIN188848
Massoumi, Chmielarska, Hennecke, Pfeifer, Fässler: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. dans Cell 2006
Human Polyclonal CYLD Primary Antibody pour ICC, IF - ABIN252428
Moranta, Regueiro, March, Llobet, Margareto, Larrarte, Larrate, Garmendia, Bengoechea: Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells. dans Infection and immunity 2010
The crystal structures representing the catalytic states of zebrafish CYLD for Met1 (Montrer DNMT1 Anticorps)- and Lys63-linked Ub chains and two distinct precatalytic states for Met1 (Montrer DNMT1 Anticorps)-linked chains are presented.
Thrombin (Montrer F2 Anticorps)-mediated MALT1 (Montrer MALT1 Anticorps) protease activation triggers acute disruption of endothelial barrier integrity via CYLD cleavage.
SPATA2 (Montrer SPATA2 Anticorps) has been described as a previously unrecognized factor in the linear ubiquitin chain assembly complex-dependent signaling pathways that serves as an adaptor between HOIP (Montrer RNF31 Anticorps) and CYLD, thereby enabling recruitment of CYLD to signaling complexes.
TLR4 (Montrer TLR4 Anticorps) activates CASPASE-8 (Montrer CASP8 Anticorps) to cleave and remove the deubiquitinase cylindromatosis (CYLD) in a TRIF (Montrer RNF138 Anticorps)- and RIPK1 (Montrer RIPK1 Anticorps)-dependent manner to disable necroptosis in macrophages.
CYLD contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 (Montrer NOX4 Anticorps) and may play a role in vascular remodeling.
this study shows that by polarization of the T cell cytokine response, CYLD can favor the development of allergic airway disease
Our findings underscore a critical tumor-suppressing role for functional intestinal epithelial CYLD in colitis-associated carcinogenesis
Deubiquitinase CYLD negatively regulates MyD88 (Montrer MYD88 Anticorps)-mediated signaling by directly interacting with MyD88 (Montrer MYD88 Anticorps) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (Montrer MYD88 Anticorps) at lysine 231.
CYLD interrupts the ERK (Montrer EPHB2 Anticorps)- and p38 (Montrer CRK Anticorps)-/AP-1 (Montrer JUN Anticorps) and c-Myc (Montrer MYC Anticorps) pathways to suppress Nrf2 (Montrer NFE2L2 Anticorps)-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.
Our data demonstrate that inefficient negative selection in the thymus of CYLD(ex7/8) mice result from a defect in mTEC maturation.
The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.
MiR (Montrer MLXIP Anticorps)-767 acted as a role of tumor promoter by targeting CYLD in human melanoma.
The data reveal SPATA2 (Montrer SPATA2 Anticorps) as a high-affinity binding partner of CYLD and HOIP (Montrer RNF31 Anticorps), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (Montrer NFKB1 Anticorps) signaling.
The current investigations identified a subset of HPV-positive HNSCCs with mutations in the genes TRAF3 (Montrer TRAF3 Anticorps) (tumor necrosis factor (Montrer TNF Anticorps) receptor-associated factor 3) and CYLD (cylindromatosis lysine 63 deubiquitinase). Defects in TRAF3 (Montrer TRAF3 Anticorps) and CYLD correlated with the activation of transcriptional factor nuclear factor kappaB, episomal HPV status of tumors, and improved patient survival.
The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes.
STAT3 (Montrer STAT3 Anticorps) and miR (Montrer MLXIP Anticorps)-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway.
CYLD Promotes TNF-alpha (Montrer TNF Anticorps)-Induced Cell Necrosis Mediated by RIP-1 (Montrer UQCRFS1 Anticorps) in Human Lung Cancer Cells
Low CYLD expression is associated with hepatocellular carcinoma.
miR20a directly repressed the expression of CYLD, leading to activation of the NFkappaB (Montrer NFKB1 Anticorps) pathway and the downstream targets, livin (Montrer BIRC7 Anticorps) and survivin (Montrer BIRC5 Anticorps), which potentially induced GC chemoresistance.
This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
deubiquitinating enzyme CYLD
, probable ubiquitin carboxyl-terminal hydrolase CYLD
, ubiquitin carboxyl-terminal hydrolase CYLD
, ubiquitin specific peptidase like 2
, ubiquitin thioesterase CYLD
, ubiquitin thiolesterase CYLD
, ubiquitin-specific-processing protease CYLD
, cylindromatosis (turban tumor syndrome)
, probable ubiquitin carboxyl-terminal hydrolase CYLD-like
, retinitis pigmentosa 1 homolog