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Aperçu des produits pour PARP1 (PARP1) Kits ELISA

Full name:
Poly (ADP-Ribose) Polymerase 1 Kits ELISA (PARP1)
Chez www.anticorps-enligne.fr sont 34 Poly (ADP-Ribose) Polymerase 1 (PARP1) Kits ELISA de 11 de différents fournisseurs disponibles. De plus, nous expédions PARP1 Anticorps (408) et PARP1 Protéines (29) et beaucoup plus de produits pour cette protéine. Un total de 499 PARP1 produits sont actuellement listés.
Synonymes:
5830444G22Rik, Adprp, Adprt, ADPRT 1, Adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, padprt-1, parp, parp-1, PARP1, ppol, sPARP-1

Plus Kits ELISA pour PARP1 partenaires d'interaction

Fruit Fly (Drosophila melanogaster) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. The results demonstrate that PARylation process in Drosophila is tightly regulated in the context of strands-breaks repair; PARP is essential during the maintenance of DNA integrity, but dispensable in the DNA repair process.

  2. A mutation of Parp also increases NAD+ levels; although, this was only observed in parkin (Montrer PARK2 Kits ELISA) mutant flies and not in the heterozygous Parp mutants, possibly owing to an increased PARP activity in the parkin (Montrer PARK2 Kits ELISA) mutants.

  3. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av (Montrer H2AFV Kits ELISA) in a nucleosome positioned in promoter regions of PARP-1-dependent genes

  4. Based on these findings, we propose a model that explains how PARP1 activity impacts nucleolar functions and, consequently, ribosomal biogenesis

  5. PARP is associated with the 5' end of Hsp70, and its enzymatic activity is rapidly induced by heat shock leading to nucleosome loss.

  6. Activation of PARP-1 overexpression in the imago results in extension of the lifespan in females and males. The lifespan increase in females with PARP-1 conditional overexpression was accompanied by decrease of fertility.

  7. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).

  8. demonstrate that this alteration specifically excludes PARP1 protein from heterochromatin and makes PARP1 unable to maintain repression of retrotransposable elements.

  9. PARP-e autoregulates Parp transcription

  10. propose that chromosomal PARP molecules become activated by developmental or environmental cues and strip nearby chromatin proteins off DNA to generate a puff

Human Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. These results provide evidence that ARTD1 regulates cell cycle re-entry and G1/S progression via cyclin E (Montrer CCNE1 Kits ELISA) expression and p27 (Montrer PAK2 Kits ELISA)(Kip 1 (Montrer CDKN1B Kits ELISA)) stability independently of its enzymatic activity, uncovering a novel cell cycle regulatory mechanism.

  2. our results indicate that carriers of different BRCA1 mutations could benefit from olaparib in a distinct way and show different toxicities to the agent, which could be especially relevant for a potential future use of PARPi as prophylactic agents in BRCA1 mutation carriers

  3. Data provide evidence that the acetylation of H2AX (Montrer H2AFX Kits ELISA) at Lys5 (Montrer AASDHPPT Kits ELISA) by TIP60 (Montrer KAT5 Kits ELISA) is required for the (ADPribosyl) ation activity and the dynamic binding of PARP-1 to chromatin after the induction of DNA damage.

  4. H. pylori-infected gastric mucosa had increased alternative non-homologous end joining, implicating that telomere shortening was caused by inflammation-mediated overproduction of reactive oxygen species and PARP-1, leading to telomere shortening

  5. In summary, the authors identified a novel mechanism by which human herpesvirus 4 LMP1 (Montrer PDLIM7 Kits ELISA) drives expression of host tumor-promoting genes by blocking generation of the inhibitory histone modification H3K27me3 through PARP1 activation.

  6. immunohistochemical BRCA1 expression in epithelial ovarian cancer holds considerable prognostic information, whereas PARP (Montrer COL11A2 Kits ELISA) expression did not influence the outcome

  7. A series of poly(ADP-ribose)polymerase (PARP)-1 inhibitors containing a novel scaffold, the 1H-thieno[3,4-d]imidazole-4-carboxamide moiety, was designed and synthesized

  8. data establish the importance of XRCC1 (Montrer XRCC1 Kits ELISA) protein complexes for normal neurological function and identify PARP1 as a therapeutic target in DNA strand break repair-defective disease

  9. Ubc9 (Montrer UBE2I Kits ELISA) plays different roles of action in antitumor agents in chemotherapy. The process requires bleomycin hydrolase (Montrer BLMH Kits ELISA) and poly(ADP-ribose) polymerase-1. The results are beneficial to deeply understanding of Ubc9 (Montrer UBE2I Kits ELISA) functions and for precise prediction of chemotherapy outcomes in tumors.

  10. Data show that the apoptotic and cytotoxic effects of BL-038 are mediated by the intrinsic mitochondria-mediated apoptotic pathway, which in turn causes the activation of caspase-9 (Montrer CASP9 Kits ELISA) and caspase-3 (Montrer CASP3 Kits ELISA), and the cleavage of poly (ADP-ribose) polymerase (PARP), to elicit apoptosis response.

Cow (Bovine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. no difference was found in the level of SBDP145 between muscles, while SBDP120 and PARP-1 cleavage products were not detected

  2. ADPRT Val762Ala and APE1 (Montrer APEX1 Kits ELISA) Asp148Glu polymorphisms are not associated with increased breast cancer risk

  3. analysis of poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites

  4. FGF2 (Montrer FGF2 Kits ELISA) stimulates poly(ADP-ribose) polymerase activity by a DNA strand breaks-independent manner which involves a mitogen-activated protein kinases (MAPK (Montrer MAPK1 Kits ELISA))-dependent pathway

Mouse (Murine) Poly (ADP-Ribose) Polymerase 1 (PARP1) interaction partners

  1. Delayed healing in ischemic and diabetic wounds is caused by PARP hyperactivity, and PARP inhibition significantly enhanced ischemic and diabetic wound healing by promoting angiogenesis.

  2. The findings highlight specific non-overlapping functions of PARP1 and PARP2 (Montrer PARP2 Kits ELISA) at H2AX (Montrer H2AFX Kits ELISA)-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 in nonhomologous end-joining-deficient cells.

  3. data establish the importance of XRCC1 (Montrer XRCC1 Kits ELISA) protein complexes for normal neurological function and identify PARP1 as a therapeutic target in DNA strand break repair-defective disease

  4. this study shows that PARP-1 inhibition plays role in puerarin-mediated protection from liver fibrosis

  5. might be involved in streptomycin ototoxicity by regulating AIF (Montrer AIFM1 Kits ELISA) translocation in cochlear hair cells

  6. Nonionizing radiofrequency exposure is capable of inducing PARP-1.

  7. our data suggest that Parp1 is involved in the plastic remodeling of chromatin structure after NT by supporting DNA repair and specific histone code modifications.

  8. ARTD1 controls osteoclast development and bone remodelling via its enzymatic activity by modulating the epigenetic marks surrounding the IL-1beta (Montrer IL1B Kits ELISA) promoter and expression of IL-1beta (Montrer IL1B Kits ELISA) and subsequently also Nfatc1 (Montrer NFATC1 Kits ELISA)/A.

  9. the role of PARP-1 in age-dependent changes in endothelial cell function and its underlying mechanism

  10. Both depletion of PARP-1 and inhibition of PARP-1 activity augmented LXR (Montrer NR1H3 Kits ELISA) ligand-induced ABCA1 (Montrer ABCA1 Kits ELISA) expression in the RAW 264.7 macrophage line and primary bone marrow-derived macrophages but did not affect LXR (Montrer NR1H3 Kits ELISA)-dependent expression of other target genes, ABCG1 (Montrer ABCG1 Kits ELISA) and SREBP-1c (Montrer SREBF1 Kits ELISA).

PARP1 profil antigène

Antigen Summary

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Alternative names and synonyms associated with PARP1

  • Poly-(ADP-ribose) polymerase (Parp) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (PARP1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (Parp1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (parp1) Elisa Kit
  • poly (ADP-ribose) polymerase family, member 1 (Parp1) Elisa Kit
  • poly ADP-ribose polymerase (Parp) Elisa Kit
  • 5830444G22Rik Elisa Kit
  • Adprp Elisa Kit
  • Adprt Elisa Kit
  • ADPRT 1 Elisa Kit
  • Adprt1 Elisa Kit
  • AI893648 Elisa Kit
  • ARTD1 Elisa Kit
  • BEST:LD21673 Elisa Kit
  • C80510 Elisa Kit
  • CG17685 Elisa Kit
  • CG17696 Elisa Kit
  • CG17718 Elisa Kit
  • CG40411 Elisa Kit
  • D.PARP Elisa Kit
  • Dm.pARTa Elisa Kit
  • Dmel\\CG40411 Elisa Kit
  • dPARP Elisa Kit
  • LD21673.3prime Elisa Kit
  • padprt-1 Elisa Kit
  • parp Elisa Kit
  • parp-1 Elisa Kit
  • PARP1 Elisa Kit
  • ppol Elisa Kit
  • sPARP-1 Elisa Kit

Protein level used designations for PARP1

CG40411-PB , CG40411-PC , Parp-PB , Parp-PC , Poly(ADP ribose) polymerase 1 , Poly(ADP)-Ribose polymerase , Poly(ADP-)Ribose polymerase , Poly(ADP-ribose) polymerase , Poly(ADP-ribose) polymerase 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) , ADP-ribosyltransferase NAD(+) , ADP-ribosyltransferase diphtheria toxin-like 1 , NAD(+) ADP-ribosyltransferase 1 , poly (ADP-ribose) polymerase family, member 1 , poly [ADP-ribose] polymerase 1 , poly(ADP-ribose) polymerase , poly(ADP-ribose) synthetase , poly(ADP-ribosyl)transferase , poly[ADP-ribose] synthase 1 , ADP-ribosyltransferase (NAD+ , ADP-ribosyltransferase 1 , ADPRT 1 , poly (ADP-ribose) polymerase) , poly(ADP-ribose) polymerase PARP-1 , poly[ADP-ribose] synthetase 1 , ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase) , PARP-1 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1 , msPARP , Poly[ADP-ribose] synthase 1

GENE ID SPECIES
3355109 Drosophila melanogaster
142 Homo sapiens
25591 Rattus norvegicus
286764 Bos taurus
397928 Xenopus laevis
396199 Gallus gallus
490385 Canis lupus familiaris
11545 Mus musculus
100689463 Cricetulus griseus
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