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anti-Human BMP10 Anticorps:
anti-Mouse (Murine) BMP10 Anticorps:
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Human Polyclonal BMP10 Primary Antibody pour IF (p), IHC (p) - ABIN1387078
Wu, Chen, Mi, Chen, Wang, Gao: Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients. dans International journal of clinical and experimental pathology 2014
Circulating Bmp10 acts via Alk1 (Montrer ACVRL1 Anticorps) to limit endothelial cell number in nascent arteries.
Data suggest BMP9/GDF2 (Montrer GDF2 Anticorps) and BMP10 synergize with TNFA (Montrer TNF Anticorps) to increase monocyte recruitment to vascular endothelial cells; process appears to be mediated mainly via ALK2/ACVR1 (Montrer ACRV1 Anticorps) (which exhibits protein kinase (Montrer CDK7 Anticorps) activity). These studies used in vitro flow monocyte adhesion assay. (BMP9 (Montrer GDF2 Anticorps) = growth differentiation factor 2 (Montrer GDF2 Anticorps); BMP10 = bone morphogenetic protein 10; TNFA (Montrer TNF Anticorps) = tumor necrosis factor alpha (Montrer TNF Anticorps); ALK2/ACVR1 (Montrer ACRV1 Anticorps) = activin A receptor type 1 (Montrer ACRV1 Anticorps))
Bone morphogenetic protein (BMP)9 (Montrer GDF2 Anticorps) and BMP10 are high affinity ligands for activin receptor-like kinase 1 (ALK1 (Montrer ACVRL1 Anticorps)).
Forced expression of BMP10 in gastric cancer (GC) cells inhibited its growth and migration, while knocking down the expression of BMP10 in GC cells promoted cell growth, migration, and metastasis.
The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells.
BMP10, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP10 signaling may play a pivotal role in disease development.
Low expression of bone morphogenetic protein-10 is associated with urothelial cancer of the bladder.
Soluble endoglin (Montrer ENG Anticorps) specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
Furin (Montrer FURIN Anticorps) is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10.
Bone morphogenetic protein-10 (BMP-10) may function as a tumor suppressor in breast cancer.
Hypertension induced expression of prohypertrophic BMP10, and the hypertrophic effect of BMP10 was modulated, at least in part, by its binding to Tcap (Montrer TCAP Anticorps) at the Z disc.
CV2 (Montrer BMPER Anticorps) binds directly to BMP10, as determined by co-immunoprecipitation, and inhibits BMP10 from initiating SMAD (Montrer SMAD1 Anticorps) signaling, as determined by luciferase reporter gene assays. BMP10 and CV2 (Montrer BMPER Anticorps) have important roles in coordinating cardiomyogenesis in progenitor cells.
result was supported by the identification of the regulation by BMP9 (Montrer GDF2 Anticorps) and BMP10 of several genes known to be involved in this process
BMP10 has an exclusive function in cardiac development, which cannot be substituted by BMP9 (Montrer GDF2 Anticorps).
Myocardin (Montrer MYOCD Anticorps) transactivated Bmp10 via binding of a serum response factor-myocardin (Montrer MYOCD Anticorps) complex to a nonconsensus CArG element in the Bmp10 promoter. A myocardin (Montrer MYOCD Anticorps)/BMP10 signaling pathway regulates cardiomyocyte proliferation & apoptosis in embryonic heart.
BMP9 (Montrer GDF2 Anticorps) and BMP10 are important in postnatal vascular remodeling of the retina and BMP10 can substitute for BMP9 (Montrer GDF2 Anticorps).
the BMP10-Tbx20 (Montrer TBX20 Anticorps) signaling cascade is important for ventricular wall development and maturation.
Results describe an essential role of bone morphogenetic protein 10 in regulating cardiac growth and chamber maturation.
The protein encoded by this gene is a member of the TGF-beta family of growth factors. Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart. In human, this protein may signal through receptor serine/threonine kinases.
bone morphogenetic protein 10
, bone morphogenetic protein 10-like
, bone morphogenetic protein-10