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Aperçu des produits pour anti-BIK (BIK) Anticorps

Full name:
anti-BCL2-Interacting Killer (Apoptosis-Inducing) Anticorps (BIK)
Chez www.anticorps-enligne.fr sont 122 BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) Anticorps de 25 de différents fournisseurs disponibles. De plus, nous expédions BIK Kits (5) et BIK Protéines (5) et beaucoup plus de produits pour cette protéine. Un total de 147 BIK produits sont actuellement listés.
Synonymes:
BIK, Biklk, BIP1, Blk, BP4, NBK, si:dkey-31f5.6
afficher tous les anticorps Gène GeneID UniProt
BIK 12124  
BIK 638 Q13323
BIK 114496  

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Réactivités les plus populaires pour anti-BIK (BIK) Anticorps

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anti-Mouse (Murine) BIK Anticorps:

anti-Human BIK Anticorps:

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anti-BIK Anticorps mieux référencés

  1. Human Polyclonal BIK Primary Antibody pour EIA, IHC (p) - ABIN358090 : Nikrad, Johnson, Puthalalath, Coultas, Adams, Kraft: The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. dans Molecular cancer therapeutics 2005 (PubMed)
    Show all 5 references for ABIN358090

  2. Human Monoclonal BIK Primary Antibody pour IP, WB - ABIN967566 : Boyd, Gallo, Elangovan, Houghton, Malstrom, Avery, Ebb, Subramanian, Chittenden, Lutz: Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. dans Oncogene 1995 (PubMed)
    Show all 5 references for ABIN967566

  3. Human Polyclonal BIK Primary Antibody pour IHC (p), WB - ABIN388114 : Gillissen, Essmann, Graupner, Stärck, Radetzki, Dörken, Schulze-Osthoff, Daniel: Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway. dans The EMBO journal 2003 (PubMed)
    Show all 3 references for ABIN388114

  4. Human Polyclonal BIK Primary Antibody pour EIA, IF - ABIN499467 : Germain, Mathai, McBride, Shore: Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. dans The EMBO journal 2005 (PubMed)
    Show all 3 references for ABIN499467

  5. Human Polyclonal BIK Primary Antibody pour IHC (p), WB - ABIN389524 : Arena, Martini, Luongo, Capelli, Larocca: Mutations of the BIK gene in human peripheral B-cell lymphomas. dans Genes, chromosomes & cancer 2003 (PubMed)
    Show all 2 references for ABIN389524

  6. Human Polyclonal BIK Primary Antibody pour WB - ABIN223382 : Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. dans Blood 2007 (PubMed)

  7. Human Polyclonal BIK Primary Antibody pour IF, WB - ABIN318742 : Mathai, Germain, Shore: BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. dans The Journal of biological chemistry 2005 (PubMed)

  8. Human Polyclonal BIK Primary Antibody pour EIA, IHC (p) - ABIN356832 : Sass, Shembade, Haimerl, Lamoureux, Hashemolhosseini, Tannapfel, Tiegs: TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. dans Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

Plus d’anticorps contre BIK partenaires d’interaction

Mouse (Murine) BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) interaction partners

  1. These studies suggest a link between Bik-mediated caspase (Montrer CASP3 Anticorps) activation and cleavage of viral proteins.

  2. OPN (Montrer SPP1 Anticorps) induces oxidative stress via the involvement of mitochondria and NOX-4 (Montrer NOX4 Anticorps). It may affect mitochondrial morphology and integrity, at least in part, via the involvement of BIK.

  3. Findings identify novel cross talk between autophagy and apoptosis, wherein targeting SQSTM1/p62 (Montrer SQSTM1 Anticorps) converts cytoprotective autophagy to an inefficient form due to cargo loading failure, leading to NBK/Bik accumulation, which triggers apoptosis.

  4. Src (Montrer SRC Anticorps) tyrosine kinase (Montrer TYRO3 Anticorps) inhibits apoptosis through the Erk1/2 (Montrer MAPK1/3 Anticorps)- dependent degradation of the death accelerator Bik.

  5. The Bik protein, even in combination with Noxa (Montrer PMAIP1 Anticorps), is not a potent suppressor of c-Myc (Montrer MYC Anticorps)-driven tumourigenesis or critical for chemotherapeutic drug-induced killing of Myc (Montrer MYC Anticorps)-driven tumours.

  6. BIKDD, a constitutively active mutant form of proapoptotic gene, BIK, effectively induces apoptosis of breast cancer cells and synergizes with lapatinib.

  7. Blk has been mapped to chromosome 15 and overexpressed in transitional B cells of A/WySnJ mice, which demonstrate a cell-autonomous defect leading to excessive apoptosis.

  8. any function of Bik in programmed cell death and stress-induced apoptosis must overlap that of other BH3-only (Montrer BBC3 Anticorps) proteins

  9. Data show that Bik and Bim (Montrer BCL2L11 Anticorps) share the role of eliminating supernumerary germ cells during the first wave of spermatogenesis, a process vital for normal testicular development.

  10. Targeted expression of BikDD, a potent proapoptotic gene driven by CCKAR (Montrer CCKAR Anticorps)-VISA (Montrer MAVS Anticorps), exhibited antitumor effects on pancreatic cancer and prolonged survival in multiple xenograft and syngeneic mouse models of pancreatic tumors with virtually no toxicity

Human BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) interaction partners

  1. These studies suggest a link between Bik-mediated caspase (Montrer CASP3 Anticorps) activation and cleavage of viral proteins.

  2. our data demonstrated that suppression of BIK in ER-positive MCF-7 cells prevents the cytotoxic effect of TAM (Montrer CCNA1 Anticorps) and favors a more aggressive phenotype, due to the molecular change of different pathways

  3. HCV RNA replication and release were significantly suppressed in BIK-depleted cells and over-expression of the RNA-dependent RNA polymerase, NS5B, was able to induce BIK expression

  4. BikDDA, a novel mutant of Bik, showed a prolonged half-life and enhanced pro-apoptotic ability in triple-negative breast cancer cells compared with BikDD.

  5. Findings identify novel cross talk between autophagy and apoptosis, wherein targeting SQSTM1/p62 (Montrer SQSTM1 Anticorps) converts cytoprotective autophagy to an inefficient form due to cargo loading failure, leading to NBK/Bik accumulation, which triggers apoptosis.

  6. Authors show that human herpesvirus 4 EBNA2 represses BIK in B-cell lymphoma-derived cell lines and that this host-virus interaction can inhibit the proapoptotic effect of transforming growth factor beta1.

  7. Data suggest BIK expression in tumor cells is not subject to direct regulation by MAP kinase (Montrer MAPK1 Anticorps) signaling; BIK expression appears to be cell-cycle-dependent and increases in G1 cell-cycle arrest which results from inhibition of MAP kinase (Montrer MAPK1 Anticorps) signaling.

  8. BIK/NBK gene expression may have important clinical implications and provide predictive, prognostic or therapeutic marker in breast cancer patients

  9. Src (Montrer SRC Anticorps) tyrosine kinase (Montrer TXK Anticorps) inhibits apoptosis through the Erk1/2 (Montrer MAPK1/3 Anticorps)- dependent degradation of the death accelerator Bik.

  10. A previously undescribed indirect epigenetic regulation of BIK in FA-C lymphoblasts is mediated by DeltaNp73, an isoform of p73 (Montrer TP73 Anticorps) lacking its transactivation domain that activates BIK through a proximal element in its promoter.

BIK profil antigène

Antigen Summary

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Alternative names and synonyms associated with BIK

  • BCL2-interacting killer (apoptosis-inducing) (BIK) anticorps
  • BCL2-interacting killer (BIK) anticorps
  • BCL2-interacting killer (Bik) anticorps
  • BCL2-interacting killer (apoptosis-inducing) (Bik) anticorps
  • BCL2-interacting killer (apoptosis-inducing) (bik) anticorps
  • BIK anticorps
  • Biklk anticorps
  • BIP1 anticorps
  • Blk anticorps
  • BP4 anticorps
  • NBK anticorps
  • si:dkey-31f5.6 anticorps

Protein level used designations for BIK

BCL2-interacting killer (apoptosis-inducing) , BCL2-interacting killer , apoptosis inducer NBK , bcl-2-interacting killer , bik-like killer protein , apoptosis-inducing NBK

GENE ID SPECIES
470232 Pan troglodytes
711479 Macaca mulatta
790946 Felis catus
12124 Mus musculus
638 Homo sapiens
114496 Rattus norvegicus
564030 Danio rerio
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