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Rat (Rattus) Dopamine d2 Receptor Kit ELISA pour Sandwich ELISA - ABIN431473
Stolyarova, Izquierdo: Distinct patterns of outcome valuation and amygdala-prefrontal cortex synaptic remodeling in adolescence and adulthood. dans Frontiers in behavioral neuroscience 2015
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Study associates polymorphisms in DRD2, DARPP-32 (Montrer PPP1R1B Kits ELISA), and COMT (Montrer COMT Kits ELISA) genes with novel category learning performance. Modeling results suggest that striatal dopaminergic genes influence selective attention processes whereas cortical genes mediate the ability to update complex rule representations.
Greater predicted DRD2 pathway prefrontal co-expression was associated with greater prefrontal activity and longer working memory reaction times in schizophrenic patients.
DRD2 A2/A1, DRD3 (Montrer DRD3 Kits ELISA) Ser9Gly, DbetaH -1021C>T, OPRM1 (Montrer OPRM1 Kits ELISA) A118G and GRIK1 (Montrer GRIK1 Kits ELISA) rs2832407C>A are not associated with alcoholism alone or in interaction.
Lowering the level of cellular FLNA (Montrer FLNA Kits ELISA) caused an elevation in RalA (Montrer rala Kits ELISA) activity and resulted in selective interference with the normal intracellular trafficking and signaling of D2R through GRK2 (Montrer ADRBK1 Kits ELISA). Knockdown of FLNA (Montrer FLNA Kits ELISA) or coexpression of active RalA (Montrer rala Kits ELISA) interfered with the recycling of the internalized D2R and resulted in the development of receptor tolerance. Active RalA (Montrer rala Kits ELISA) was found to interact with GRK2 (Montrer ADRBK1 Kits ELISA) to sequester it from D2R.
Using the human glycosylated native conformational D2R, study shows the importance of D2R extracellular N-terminus in regulating receptor availability at the cell surface, human anti-D2R antibody binding, and potential pathogenic mechanisms of these antibodies.
this study shows that D3R is palmitoylated more extensively than D2R even though the carboxyl terminus tails of D2R and D3R are highly homologous, and thus provides a new clue regarding the consensus sequence for palmitoylation.
High frequencies of the DRD2/ANKK1 A1 allele were present in Mexican populations
rs1076560(T) imparts a small but reliable risk for schizophrenia. and was associated with impaired verbal fluency and comprehension in schizophrenia. It was associated with impaired verbal fluency and comprehension in schizophrenia, and disrupted a binding site for the splicing factor ZRANB2. This work implicates rs1076560(T) as one possible risk factor for schizophrenia in the Han Chinese population.
A combined haplotype (9R-A2) of DAT-1 (Montrer SLC6A3 Kits ELISA) and DRD2 genes was associated with the murderer phenotype among Pakistani violent criminal inmates.
The Parkinson's disease-associated LRRK2 (Montrer LRRK2 Kits ELISA) mutant G2019S impairs DRD1 (Montrer DRD1 Kits ELISA) internalization, leading to an alteration in signal transduction. The mutant forms of LRRK2 (Montrer LRRK2 Kits ELISA) also affect receptor turnover by decreasing the rate of DRD2 trafficking from the Golgi complex to the cell membrane.
Studied a novel Dopamine Receptor 2 (DRD2) G/A SNP for resistance to fescue toxicosis.
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration
Results show that deleted in colorectal cancer (Montrer DCC Kits ELISA) receptors contribute to the dynamic refinement of dopamine D1 and D2 receptor expression in striatal regions across adolescence. The age-dependent expression of dopamine receptor in C57BL6 mice shows marked differences from previous characterizations in rats.
The expression of Klf15 (Montrer KLF15 Kits ELISA) is increased during neuropathic pain. TNF-alpha (Montrer TNF Kits ELISA) regulates the expression of Klf15 (Montrer KLF15 Kits ELISA). KLF15 (Montrer KLF15 Kits ELISA) regulates the expression of dopamine D2 receptor. KLF15 (Montrer KLF15 Kits ELISA) regulates neuropathic pain in mouse models.
MIce that selectively lack dopamine type 2 receptors (D2Rs) from pituitary lactotropes have chronic high prolactin (Montrer PRL Kits ELISA) levels associated with increased body weight, marked increments in fat depots, adipocyte size, and serum lipids, and a metabolic phenotype.
Data show that the fine control of excitatory transmission by glycogen synthase kinase 3 (Montrer GSK3a Kits ELISA) requires recruitment of dopamine D2-receptors and depends on the presence of serotonin 5-HT1A (Montrer HTR1A Kits ELISA)-receptors.
Study found no differences in the D2R binding following ten-day methamphetamine administration and seven-day withdrawal, possibly suggesting that alterations in the D2R are not involved in the emergence of anxiety-related symptoms and the development of psychomotor sensitization during withdrawal
Results suggest that the role of reduced D2 receptor in obesity lies not in increasing appetitive motivation and generating compulsive eating but rather in altering activity and energy expenditure, favoring reduced behavioral expenditure of energy. More broadly, these data are consistent with a fundamental role for dopamine in regulating behavioral energy expenditure.
D2R agonist treatment blocks tumor growth, induces regression of the aberrant blood supply and normalizes blood vessels. An anti-Vegf therapy is also effective to restrain tumor growth and improves vascular remodeling. Importantly, only the combination treatment suppresses intratumoral hemorrhage and restores blood vessel perfusion, suggesting that it might represent an attractive therapy targeting tumor vasculature
Data indicate a contribution of D2 dopamine receptors to the effects of repetitive transcranial magnetic stimulation (rTMS) on postsynaptic density protein-95 (PSD-95 (Montrer DLG4 Kits ELISA)) and cyclin-dependent kinase 5 (CDK5 (Montrer CDK5 Kits ELISA)) levels.
Mapped associations occur between changes in D2 and D3 dopamine receptor (Montrer DRD3 Kits ELISA) occupancy and brain hemodynamics
These data provide evidence for a predisposition to self-administer cocaine based on dopamine D2 receptor availability, and demonstrate that the brain dopamine system responds rapidly following cocaine exposure.
The amount of dopamine d1 receptor (Montrer DRD1 Kits ELISA), dopamine D2 receptor, and follicle stimulating hormone receptor (Montrer FSHR Kits ELISA) mRNA were quantified in ovarian tissues in anestrous and mares expressing estrus during the breeding season are reported.
The pig DRD2 gene was cloned, investigated its distribution in tissues and polymorphisms were identified.
The increase in NOS (Montrer NOS Kits ELISA) protein seen in both the endothelium and vascular smooth muscle in response to cerebral vasospasm is enhanced by dopamine in a D(2)R-dependent mechanism.
Findings suggest a role for dopamine D1-like receptor (Montrer DRD1 Kits ELISA) Dop1R2 in the repression of genes that coordinate metamorphosis.
Results suggest that the activation state of DAMB protein contributes to oxidative stress susceptibility in Drosophila and lead to a proposed model for paraquat neurotoxicity.
Dopamine D2 receptor play role in memory consolidation.
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia\; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
D(2) dopamine receptor
, dopamine D2 receptor
, dopamine receptor D2 isoform
, seven transmembrane helix receptor
, D2 dopamine receptor
, Dopamine D2 receptor
, dopamine receptor D2b
, dopamine D2 receptor 1
, dopamine D2 receptor 2
, D2 receptor
, dopamine receptor 2
, D(2) dopamine receptor A
, D2R 1
, dopamine receptor D2
, dopamine receptor 2 protein
, D[]-like receptor
, dopamine receptor in mushroom bodies
, dopamine-2 receptor