Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Select your species
Cdon is required to localize N-cadherin (Montrer CDH2 Kits ELISA) to the cell membrane in migratory neural crest cells for directed migration.
In the developing optic vesicle, Cdon predominantly localizes to the basolateral side of neuroepithelial cells, promotes the enlargement of the neuroepithelial basal end-foot and traps Hedgehog (Montrer SHH Kits ELISA) protein, thereby limiting its dispersion.
We identified a novel heterozygous nonsense CDON mutation in a case of Pituitary Stalk Interruption Syndrome who presented with neonatal hypoglycemia and cholestasis
CDO (Montrer CDO1 Kits ELISA) is required for proliferation and survival of lung cancer cells via Hh signaling.
These data support the view that cell-adhesion molecule (Montrer MCAM Kits ELISA)-related/downregulated by oncogenes (CDON) acts as a tumor suppressor in neuroblastomas, and that CDON is tightly regulated by miRNAs.
Single-nucleotide polymorphism in CDON is associated with biochemical recurrence in prostate cancer.
Mutations in the CDON cause holoprosencephaly. (Review)
We found that CDON is overexpressed in prostate cancer
CDON must associate with both ligand and other hedgehog (Montrer SHH Kits ELISA)-receptor components, particularly PTCH1 (Montrer PTCH1 Kits ELISA), for signaling to occur and disruption of the latter interactions is a mechanism of holoprosencephaly.
Hedgehog (Montrer SHH Kits ELISA) proteins interact with cell adhesion molecule (Montrer MCAM Kits ELISA), down-regulated by oncogenes (CDO (Montrer CDO1 Kits ELISA)) and brother of CDO (BOC (Montrer BOC Kits ELISA)) in a conserved manner
CDO (Montrer CDO1 Kits ELISA) and BOC (Montrer BOC Kits ELISA) play a role in differentiation of cells in the skeletal muscle lineage
CDO (Montrer CDO1 Kits ELISA) and BOC (Montrer BOC Kits ELISA) forms complexes with specific cadherins that mediate some of the promyogenic effects of cell-cell contact.
Study assessed the role of the Shh (Montrer SHH Kits ELISA) receptor Cdon in the development of ventral tegmental area and substantia nigra pars (Montrer EPRS Kits ELISA) compacta dopamine neurons. Results suggest that Cdon plays an important role in the encoding of diversity within the population of dopamine neurons of the midbrain, influencing both the development of the mesocortical dopamine pathway as well as behavioral outputs that involve this neural circuitry.
Results suggest that a promyogenic cell adhesion molecule (Montrer MCAM Kits ELISA) Cdo (Montrer CDO1 Kits ELISA) signaling is critical for Inward rectifier potassium channel Kir2.1 (Montrer KCNJ2 Kits ELISA) activities in the induction of myogenic differentiation.
PKN2 (Montrer PKN2 Kits ELISA) formed complexes with Cdo (Montrer CDO1 Kits ELISA), APPL1 (Montrer APPL1 Kits ELISA) and AKT (Montrer AKT1 Kits ELISA) via its C-terminal region and this interaction appeared to be important for induction of AKT (Montrer AKT1 Kits ELISA) activity as well as myoblast differentiation.
that Cdon participates in oligodendrocyte differentiation and myelination, most likely in the initial stages of development
Suggest that Cdo (Montrer CDO1 Kits ELISA) is required for the full Shh (Montrer SHH Kits ELISA) signaling activation to induce efficient dopaminergic neuron neurogenesis.
Rescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1 (Montrer PTCH1 Kits ELISA).
Cx43 (Montrer GJA1 Kits ELISA) physically interacts with Cdo (Montrer CDO1 Kits ELISA) to form dynamic complexes during myoblast differentiation
Stim1 (Montrer STIM1 Kits ELISA) protein levels were decreased in Cdo (Montrer CDO1 Kits ELISA)-deficient perinatal hindlimb muscles or primary myoblasts; this correlates with defective NFATc3 (Montrer NFATC3 Kits ELISA) activation in Cdo (Montrer CDO1 Kits ELISA)(-/-) myoblasts upon differentiation.
ASK1 (Montrer MAP3K5 Kits ELISA) and TAK1 (Montrer NR2C2 Kits ELISA) function as MAP3 kinases in Cdo (Montrer CDO1 Kits ELISA)-mediated p38MAPK (Montrer MAPK14 Kits ELISA) activation to promote myogenic differentiation.
Gas1 (Montrer GAS1 Kits ELISA) cooperates with Cdo (Montrer CDO1 Kits ELISA) and promotes myogenic differentiation via activation of p38MAPK (Montrer MAPK14 Kits ELISA)
This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis.
Cdon homolog (mouse)
, surface glycoprotein, Ig superfamily member
, cell adhesion molecule-related/down-regulated by oncogenes
, Cdon homolog
, immunoglobulin superfamily member
, CAM-related/down-regulated by oncogenes
, immunoglobulin superfamily member CDO
, oncogene-regulated cell adhesion molecule
, cysteine dioxygenase type 1
, cysteine dioxygenase type I