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Human Polyclonal ATG7 Primary Antibody pour IF, IHC (p) - ABIN388522
Baehrecke: Autophagy: dual roles in life and death? dans Nature reviews. Molecular cell biology 2005
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Human Polyclonal ATG7 Primary Antibody pour ICC, IF - ABIN269462
Park, Lee, Kim, Lee, Lee, Kim, Jang, Choi, Kwon, Kim: A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. dans Cancer research 2007
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Human Polyclonal ATG7 Primary Antibody pour IHC (p), WB - ABIN388521
Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. dans Nature reviews. Molecular cell biology 2005
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Human Polyclonal ATG7 Primary Antibody pour IHC (p), WB - ABIN4282130
Lee, Chen, Su, Chueh: Sirtuin 1 (SIRT1) Deacetylase Activity and NAD⁺/NADH Ratio Are Imperative for Capsaicin-Mediated Programmed Cell Death. dans Journal of agricultural and food chemistry 2015
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Human Polyclonal ATG7 Primary Antibody pour EIA, WB - ABIN118061
Aoki, Kobayashi, Tanida, Hatano, Komori, Matsumoto, Nishioka, Uemura: [A difficult case of esophageal and gastric double cancer with pleural and pericardial effusion following chemo-radiotherapy (CRT)] dans Gan to kagaku ryoho. Cancer & chemotherapy 2008
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Human Monoclonal ATG7 Primary Antibody pour WB - ABIN387793
Metzger, Saukko, Van Che, Tong, Puder, Riess, Nguyen: Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. dans Human genetics 2010
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Human Polyclonal ATG7 Primary Antibody pour IHC (p), WB - ABIN388520
Greenberg: Degrade or die: a dual function for autophagy in the plant immune response. dans Developmental cell 2005
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Human Polyclonal ATG7 Primary Antibody pour IF, IHC (p) - ABIN388523
Levine: Eating oneself and uninvited guests: autophagy-related pathways in cellular defense. dans Cell 2005
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knockdown of autophagy genes ATG5 (Montrer ATG5 Anticorps) or ATG7 resulted in reduced hematopoietic stem/progenitor cell frequencies in vitro as well as in vivo.
Nine of the 32 (28.1%) iCCA (Montrer PRRT2 Anticorps) patients had gene mutations at chromosome 3p, totaling 11 mutations across five genes. Those included five (15.6%) BAP1 (Montrer RNF2 Anticorps) mutations, two each (6.3%) of CACNA2D3 (Montrer CACNA2D3 Anticorps) and RASSF1 (Montrer RASSF1 Anticorps) mutations, and one each (3.1%) of ATG7 and PLCD1 (Montrer PLCD1 Anticorps) mutations. Six (18.8%) cases had concurrent loss of chromosome 3p and gene mutations.
knockdown of ATG7 results in decreased glycolysis and increased flux of labeled carbons through the mitochondrial tricarboxylic acid cycle.
SNP rs11706903 in ATG7 was not associated with systemic lupus erythematosus I Chinese Han population.
low serum ATG7 is associated with ulcerative colitis
The U2AF35 (Montrer U2AF1 Anticorps)(S34F) mutation alters interaction with CFIm59 (Montrer CPSF7 Anticorps), leading to increased use of a distal cleavage and polyadenylation site in the ATG7 pre-mRNA, decreasing levels of ATG7 protein and defective autophagy, ultimately leading to transformation.
the inhibition of Atg7 appears to be a valid strategy to enhance chemosensitivity, and it could indeed improve outcomes in acute myeloid leukemia (Montrer BCL11A Anticorps) therapy.
Our data demonstrate that HOTAIR promotes the activation of autophagy in HCC (Montrer FAM126A Anticorps) cells by upregulating the expression of the autophagy-related genes ATG3 (Montrer ATG3 Anticorps) and ATG7.
Autophagy-related gene ATG7 was validated as a target of miR-17 seed family.
the upregulation of autophagy-related gene (Atg) and wingless/int1 (Montrer WNT1 Anticorps) (Wnt (Montrer WNT2 Anticorps)) signaling during BMP-2 (Montrer BMP2 Anticorps)-mediated human osteoblastic differentiation, was examined.
Atg7 is critical for the survival of midbrain dopaminergic (mDA) neurons in physiological condition. Atg7 is up-regulated when exposed to MPTP (Montrer PTPN2 Anticorps), but unlike in the control mice, chronic MPTP (Montrer PTPN2 Anticorps) treatment did not lead to loss of mDA neurons in Atg7 conditional knockout mice. These results suggest that excessive Atg7-involved autophagy in the pathological condition has deleterious effects on the survival of mDA neurons.
It shows that AMBRA1 (Montrer AMBRA1 Anticorps), but not ATG7, plays a role in TCR-mediated control of glycolytic factors and mitochondrial mass, while both AMBRA1 (Montrer AMBRA1 Anticorps) and ATG7 are required for autolysosome formation.
Collectively, these data reveal that miR (Montrer MLXIP Anticorps)-20a inhibits autophagic response and promotes BCG (Montrer SLC11A1 Anticorps) survival in macrophages by targeting ATG7 and ATG16L1 (Montrer ATG16L1 Anticorps).
Beta-Atg7 (-/-) mice had proinsulin (Montrer INS Anticorps)-containing sequestosome 1 (p62 (Montrer SQSTM1 Anticorps) [also known as SQSTM1 (Montrer SQSTM1 Anticorps)])(+) aggregates in beta cells, indicating proinsulin (Montrer INS Anticorps) is regulated by autophagy in vivo. Short-term bafilomycin-A1 treatment and ATG5 (Montrer ATG5 Anticorps)/7 knockdown increased steady-state proinsulin (Montrer INS Anticorps) and hormone precursor chromogranin A (Montrer CHGA Anticorps) content. ATG5 (Montrer ATG5 Anticorps)/7 knockdown also increased glucose- and non-fuel-stimulated insulin (Montrer INS Anticorps) secretion.
gene deletion results in accumulation of RPE65 (Montrer RPE65 Anticorps) variant M450 in the retinal pigment epithelium
A conditional deletion of Atg7 in hepatocytes leads to hepatomegaly and in aged animals to liver tumors.
this study shows that knockdown of ATG7 enhances macrophage-associated (Montrer CD163 Anticorps) phagocytosis and intracellular killing of Pseudomonas aeruginosa
specific ablation of autophagy gene 7 (Atg7) from kidney proximal tubules worsened Lipopolysaccharide-induced acute kidney injury.
This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes.
autophagy-related protein 7
, Autophagy-related protein 7
, ATG7 autophagy related 7 homolog
, ATG12-activating enzyme E1 ATG7
, ubiquitin activating enzyme E1-like protein
, ubiquitin-activating enzyme E1-like protein
, ubiquitin-like modifier-activating enzyme ATG7
, autophagy-related 7
, autophagy related 7 homolog
, potential E1-like Atg12p-Atg5p conjugation enzyme Atg7