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Aperçu des produits pour anti-MAPK14 (MAPK14) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase 14 Anticorps (MAPK14)
Chez sont 177 Mitogen-Activated Protein Kinase 14 (MAPK14) Anticorps de 23 de différents fournisseurs disponibles. De plus, nous expédions MAPK14 Kits (47) et MAPK14 Protéines (34) et beaucoup plus de produits pour cette protéine. Un total de 289 MAPK14 produits sont actuellement listés.
186F5S, anon-sts23, AP22.98, AP22_98, ATMPK14, BG:DS00797.3, CG7393, CRK1, csbp, Csbp1, Csbp2, CSPB1, D-p38, D-p38 MAPK, D-p38b, Dmel\\CG7393, Dmp38b, Dm p38b, Dp38, dp38b, ESTS:186F5S, Exip, Hog, mapk14a, mitogen-activated protein kinase 14, Mpk34C, mxi2, p38, p38 beta, p38 MAPK, p38-alpha, p38a, p38alpha, p38B, p38beta, p38Hog, p38Kb, p38MAPK, Prkm14, Prkm15, RK, sapk2, sapk2a
afficher tous les anticorps Gène GeneID UniProt
MAPK14 1432 Q16539
MAPK14 26416 P47811
MAPK14 81649  

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anti-Human MAPK14 Anticorps:

anti-Mouse (Murine) MAPK14 Anticorps:

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anti-MAPK14 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal MAPK14 Primary Antibody pour IHC (fro), WB - ABIN372694 : Lin, Minden, Martinetto, Claret, Lange-Carter, Mercurio, Johnson, Karin: Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. dans Science (New York, N.Y.) 1995 (PubMed)
    Show all 5 references for ABIN372694

  2. Human Polyclonal MAPK14 Primary Antibody pour EIA, WB - ABIN4620527 : Cheung, Campbell, Nebreda, Cohen: Feedback control of the protein kinase TAK1 by SAPK2a/p38alpha. dans The EMBO journal 2003 (PubMed)
    Show all 5 references for ABIN4620527

  3. Human Polyclonal MAPK14 Primary Antibody pour EIA, WB - ABIN359424 : Dean, Sarsfield, Tsounakou, Saklatvala: p38 Mitogen-activated protein kinase stabilizes mRNAs that contain cyclooxygenase-2 and tumor necrosis factor AU-rich elements by inhibiting deadenylation. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN359424

  4. Human Monoclonal MAPK14 Primary Antibody pour ICC, FACS - ABIN1724830 : Li, Zheng, Li, Ma: Unfractionated heparin inhibits lipopolysaccharide-induced inflammatory response through blocking p38 MAPK and NF-?B activation on endothelial cell. dans Cytokine 2012 (PubMed)
    Show all 2 references for ABIN1724830

  5. Human Polyclonal MAPK14 Primary Antibody pour IHC (p), WB - ABIN197012 : Zheng, Reynolds, Jo, Wersto, Han, Xiao: Intracellular acidosis-activated p38 MAPK signaling and its essential role in cardiomyocyte hypoxic injury. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)
    Show all 2 references for ABIN197012

  6. Human Polyclonal MAPK14 Primary Antibody pour WB - ABIN197496 : van den Blink, Juffermans, ten Hove, Schultz, van Deventer, van der Poll, Peppelenbosch: p38 mitogen-activated protein kinase inhibition increases cytokine release by macrophages in vitro and during infection in vivo. dans Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 2 references for ABIN197496

  7. Cow (Bovine) Polyclonal MAPK14 Primary Antibody pour WB - ABIN2792184 : Choi, Kim, Kang, Bae, Cho, Soh, Kim, Kang, Chung, Lee, Lee: Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells. dans The Journal of biological chemistry 2006 (PubMed)

  8. Human Polyclonal MAPK14 Primary Antibody pour IHC (p), WB - ABIN197010 : Kim, Tannenbaum, White: Global phosphoproteome of HT-29 human colon adenocarcinoma cells. dans Journal of proteome research 2005 (PubMed)

  9. Cow (Bovine) Polyclonal MAPK14 Primary Antibody pour IHC, WB - ABIN2792183 : Alemán, Schierloh, de la Barrera, Musella, Saab, Baldini, Abbate, Sasiain: Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis patients. dans Infection and immunity 2004 (PubMed)

Plus d’anticorps contre MAPK14 partenaires d’interaction

Cow (Bovine) Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. results suggest that ET-1 (Montrer EDN1 Anticorps)-induced activation of proMMP-2 is mediated via cross-talk between NADPH oxidase (Montrer NOX1 Anticorps)-PKCalpha (Montrer PKCa Anticorps)-p(38)MAPK (Montrer MAPK1 Anticorps) and NFkappaB-MT1MMP (Montrer MMP14 Anticorps) signaling pathways along with a marked decrease in TIMP-2 (Montrer TIMP2 Anticorps) expression in the cells

  2. cross-talk between p(38)MAPK (Montrer MAPK1 Anticorps) and Gialpha play a pivotal role for full activation of cPLA2 (Montrer PLA2G4A Anticorps) during ET-1 (Montrer EDN1 Anticorps) stimulation of pulmonary artery smooth muscle cells.

  3. MAPK14 signalling pathway is largely involved in heat-induced sperm damage.

  4. p38 MAPK is an early redox sensor in the laminar shear stress with hydrogen peroxide being a signaling mediator.

  5. Blockade of p38 enhances chondrocyte phenotype in monolayer culture and may promote more efficient cartilage tissue regeneration for cell-based therapies.

  6. p38 phosphorylation and MMP13 (Montrer MMP13 Anticorps) expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  7. These data suggest that the p38 and JNK (Montrer MAPK8 Anticorps) signaling pathways play pivotal roles in PRRSV replication and may regulate immune responses during virus infection.

  8. findings support the hypothesis that ischemic factor stimulation of the blood-brain barrier Na-K-Cl cotransporter (Montrer SLC12A1 Anticorps) involves activation of p38 and JNK (Montrer MAPK8 Anticorps) MAPKs

  9. These data suggest a differential requirement of JNK1 (Montrer MAPK8 Anticorps) and p38 MAPK in TNF (Montrer TNF Anticorps) regulation of E2F1 (Montrer E2F1 Anticorps). Targeted inactivation of JNK1 (Montrer MAPK8 Anticorps) at arterial injury sites may represent a potential therapeutic intervention for ameliorating TNF (Montrer TNF Anticorps)-mediated EC dysfunction.

  10. p38 MAPK (MAPK14) is redox-regulated in reactive oxygen species-dependent endothelial barrier dysfunction.

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. ROS (Montrer ROS1 Anticorps)/JNK (Montrer MAPK8 Anticorps)/p38/Upd (Montrer UROD Anticorps) stress responsive module restores tissue homeostasis. This module is not only activated after cell death induction but also after physical damage and reveals one of the earliest responses for imaginal disc regeneration.

  2. Taken together, our findings indicate that the p38 MAP Kinase is an integral component of the core circadian clock of Drosophila in addition to playing a role in stress-input pathways.

  3. Data show that the genetic interaction between p38b MAPK (Montrer MAPK1 Anticorps) and Rack1 (Montrer GNB2L1 Anticorps) controls muscle aggregate formation, locomotor function, and longevity.

  4. The interaction of any of several Drosophila Delta class glutathione transferases and p38b mitogen-activated protein kinase (Montrer MAPK1 Anticorps) can affect the substrate specificity of either enzyme, which suggests induced conformational changes affecting catalysis.

  5. found a correlation between the depth of integration of individual p38 kinases into the protein interaction network and their functional significance; propose a central role of p38b in the p38 signaling module with p38a and p38c playing more peripheral auxiliary roles

  6. Loss of p38 MAPK causes early lethality and precipitates age-related motor dysfunction and stress sensitivity.

  7. The p38 pathway-mediated stress response contribute to Drosophila host defense against microbial infection.

  8. p38b MAPK (Montrer MAPK1 Anticorps) plays a crucial role in the balance between intestinal stem cell proliferation and proper differentiation in the adult Drosophila midgut.

  9. the D-p38b gene is regulated by the DREF (Montrer ZBED1 Anticorps) pathway and DREF (Montrer ZBED1 Anticorps) is involved in the regulation of proliferation and differentiation of Drosophila ISCs (Montrer NFS1 Anticorps) and progenitors

Horse (Equine) Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. p38 mitogen-activated protein kinase is crucial for bovine papillomavirus type-1 transformation of equine fibroblasts.

  2. p38 Mitogen-activated protein kinase (MAPK (Montrer MAPK1 Anticorps)) is essential for drug-induced COX-2 (Montrer PTGS2 Anticorps) expression in leukocytes, suggesting that p38 MAPK is a potential target for anti-inflammatory therapy.

  3. These findings support a function for p38 MAPK in equine neutrophil migration and suggest the potential for the ability of p38 MAPK inhibition to limit neutrophilic inflammation in the laminae during acute laminitis.

  4. Cultured equine digital vein endothelial cells were exposed to lipopolysaccharide and phosphorylation of p38 MAPK was assessed by Western blotting using phospho-specific antibodies.

Human Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. Interestingly, pre-treatment of cells with reactive oxygen species inhibitor and p38 (Montrer CRK Anticorps) inhibitor significantly decreases bauerenol-induced cytotoxicity, Bax (Montrer BAX Anticorps) upregulation, and p38 (Montrer CRK Anticorps) activation

  2. P38 MAPK, phosphorylated P38 MAPK, and RAC2 (Montrer RAC2 Anticorps) regulated in mutual feedback and negative feedback regulatory pathways, resulting in the radioresistance of G0 cells.

  3. Nur77 (Montrer NR4A1 Anticorps) decreases ET-1 (Montrer EDN1 Anticorps) expression by suppressing NF-kappaB (Montrer NFKB1 Anticorps) and p38 MAPK.

  4. The antioxidant N-acetylcysteine (NAC (Montrer NLRP1 Anticorps)) blocked the AF-induced increase of reactive oxygen species (ROS (Montrer ROS1 Anticorps)) production, the reduction of total EGFR (Montrer EGFR Anticorps), and the phosphorylation of multiple nodes in EGFR (Montrer EGFR Anticorps)/MAPK (Montrer MAPK1 Anticorps) signaling pathway. P38MAPK inhibitor SB203580, but not inhibitors of EGFR (Montrer EGFR Anticorps) (erlotinib), ERK (Montrer EPHB2 Anticorps) (FR180204) and JNK (Montrer MAPK8 Anticorps) (SP600125), suppressed AF-induced phosphorylation of EGFR (Montrer EGFR Anticorps)/p38MAPK/MAPKAPK2 (Montrer MAPKAPK2 Anticorps)/Hsp27 (Montrer HSPB1 Anticorps)

  5. Potassium supplementation has a blocking effect against salt-loading-induced IL-17A (Montrer IL17A Anticorps) production in T lymphocytes, and the protective effect was mediated through suppression of p38/MAPK-SGK1 (Montrer SGK1 Anticorps) pathway.

  6. Alpha-toxin (Montrer PLC Anticorps)-mediated permeabilization of the plasma membrane of airway epithelial cells to small cations in association with membrane potential changes results in the activation of p38 MAP kinase.

  7. A family-based genome-wide association study reveals an association of spondyloarthritis with MAPK14.

  8. LDL(-) promotes p38 MAPK phosphorylation through TLR4 (Montrer TLR4 Anticorps) and PI3k (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps) pathways. Phosphorylation of p38 MAPK is involved in NF-kB, AP-1 (Montrer FOSB Anticorps) and CREB (Montrer CREB1 Anticorps) activation, leading to LDL(-)-induced cytokine release in monocytes.

  9. acetyl-CoA carboxylase 1 (Montrer ACACA Anticorps) and senescence regulation in human fibroblasts involves oxidant mediated p38 MAPK activation

  10. We found out that the link between CIRP (Montrer CIRBP Anticorps) and Snail (Montrer SNAI1 Anticorps) is mediated by ERK (Montrer EPHB2 Anticorps) and p38 (Montrer CRK Anticorps) pathways. EMT (Montrer ITK Anticorps) is a critical component of carcinoma metastasis and invasion. As demonstrated in this study, the biological role of CIRP (Montrer CIRBP Anticorps) in EMT (Montrer ITK Anticorps) may explain why CIRP (Montrer CIRBP Anticorps) overexpression has been associated with a bad prognosis in cancer patients.

Mouse (Murine) Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. miR (Montrer MLXIP Anticorps)-128 overexpression significantly downregulated the expression levels of P38 (Montrer CRK Anticorps) andP-P38 (Montrer CRK Anticorps).

  2. Phosphorylation levels of P38 (Montrer CRK Anticorps) and JNK (Montrer MAPK8 Anticorps) in siRNA-TMEM16A (Montrer ANO1 Anticorps) group were lower than that of the Model group. Thus, TMEM16A (Montrer ANO1 Anticorps) is one of the critical components of a signal transduction pathway that links renal injury to podocyte apoptosis in DN.

  3. Findings revealed that fluoxetine protects against IL-1beta (Montrer IL1B Anticorps)-induced neuronal apoptosis via p38 (Montrer CRK Anticorps)-p53 (Montrer TP53 Anticorps) dependent pathway, which give us an insight into the potential of fluoxetine in terms of opening up novel therapeutic avenues for neurological diseases including stroke

  4. Data indicate that in baicalein (BAI)-treated groups following AngII-infusion, p38-MAPK and JNK (Montrer MAPK8 Anticorps) signaling were attenuated.

  5. Cathepsin S (Montrer CTSS Anticorps) activity controls injury-related vascular remodeling via TLR2 (Montrer TLR2 Anticorps)/p38MAPK/PI3K/Akt (Montrer AKT1 Anticorps)/p-HDAC6 (Montrer HDAC6 Anticorps) signaling pathway.

  6. TRADD (Montrer TRADD Anticorps) knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1 (Montrer NR2C2 Anticorps)/p38 MAPK but not AKT (Montrer AKT1 Anticorps) phosphorylation

  7. p38alpha MAPK (Montrer MAPK1 Anticorps) facilitates plasma membrane insertion of MRP2 (Montrer ABCC2 Anticorps) by cAMP, whereas p38beta (Montrer MAPK11 Anticorps) MAPK (Montrer MAPK1 Anticorps) mediates retrieval of PM-MRP2 (Montrer ABCC2 Anticorps) by taurolithocholate.

  8. propose that active p38-Mapk14/11 act as enablers, and Erk1/2 (Montrer MAPK1/3 Anticorps) as drivers, of primitive endoderm differentiation during inner cell mass lineage specification and segregation.

  9. Double deficiency of p38alpha and p38beta (Montrer MAPK11 Anticorps) in naive CD4 (Montrer CD4 Anticorps)(+) T cells resulted in an attenuation of MAPK (Montrer MAPK1 Anticorps)-activated protein kinase (Montrer CDK7 Anticorps) (MK)-dependent mTOR (Montrer FRAP1 Anticorps) signaling after T cell receptor engagement, and enhanced their differentiation into regulatory T cells under appropriate inducing conditions.

  10. Wnt3a (Montrer WNT3A Anticorps) induces Osx (Montrer SP7 Anticorps) expression via p38 MAPK signaling in dental follicle cells. Wnt3a (Montrer WNT3A Anticorps)-induced Osx (Montrer SP7 Anticorps) expression was inhibited in the presence of p38 mitogen-activated protein kinase (MAPK (Montrer MAPK1 Anticorps)) inhibitors (SB203580 and SB202190) at gene and protein levels, as assessed by real-time PCR and immunocytohistochemistry, respectively.

Rabbit Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. These findings suggest that the TQ-induced production of ROS (Montrer ROS1 Anticorps) causes dedifferentiation through the ERK (Montrer MAPK1 Anticorps) pathway and inflammation through the PI3K and p38 pathways in rabbit articular chondrocytes.

  2. These results suggest that p38 MAPK signal transduction pathway is critical to NO-induced chondrocyte apoptosis, and p38 plays a role by way of stimulating NF-kappaB (Montrer NFKB1 Anticorps), p53 (Montrer TP53 Anticorps) and caspase-3 (Montrer CASP3 Anticorps) activation.

Pig (Porcine) Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 (Montrer IL10 Anticorps) production through p38 MAPK activation.

  2. JNK (Montrer MAPK8 Anticorps) plays an active role in fragmentation of pig oocytes and p38 MAPK is not involved in this process.[p38MAPK]

  3. Retinal ischemia-reperfusion alters expression of mitogen-activated protein kinases, particularly ERK1/2 (Montrer MAPK1/3 Anticorps), in the neuroretina and retinal arteries.

Xenopus laevis Mitogen-Activated Protein Kinase 14 (MAPK14) interaction partners

  1. cytochrome c (Montrer CYCS Anticorps) microinjection induces p38 phosphorylation through caspase-3 (Montrer CASP3 Anticorps) activation, and caspase (Montrer CASP3 Anticorps) inhibition reduces p38 activation induced by osmostress, indicating that a positive feedback loop is engaged by hyperosmotic shock

MAPK14 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAPK14

  • mitogen-activated protein kinase 14 (MPK14) anticorps
  • mitogen-activated protein kinase 14 (MAPK14) anticorps
  • mitogen-activated protein kinase 14 (Mapk14) anticorps
  • CG7393 gene product from transcript CG7393-RA (p38b) anticorps
  • mitogen activated protein kinase 14 (Mapk14) anticorps
  • mitogen-activated protein kinase 14 (mapk14) anticorps
  • 186F5S anticorps
  • anon-sts23 anticorps
  • AP22.98 anticorps
  • AP22_98 anticorps
  • ATMPK14 anticorps
  • BG:DS00797.3 anticorps
  • CG7393 anticorps
  • CRK1 anticorps
  • csbp anticorps
  • Csbp1 anticorps
  • Csbp2 anticorps
  • CSPB1 anticorps
  • D-p38 anticorps
  • D-p38 MAPK anticorps
  • D-p38b anticorps
  • Dmel\\CG7393 anticorps
  • Dmp38b anticorps
  • Dm p38b anticorps
  • Dp38 anticorps
  • dp38b anticorps
  • ESTS:186F5S anticorps
  • Exip anticorps
  • Hog anticorps
  • mapk14a anticorps
  • mitogen-activated protein kinase 14 anticorps
  • Mpk34C anticorps
  • mxi2 anticorps
  • p38 anticorps
  • p38 beta anticorps
  • p38 MAPK anticorps
  • p38-alpha anticorps
  • p38a anticorps
  • p38alpha anticorps
  • p38B anticorps
  • p38beta anticorps
  • p38Hog anticorps
  • p38Kb anticorps
  • p38MAPK anticorps
  • Prkm14 anticorps
  • Prkm15 anticorps
  • RK anticorps
  • sapk2 anticorps
  • sapk2a anticorps

Protein level used designations for MAPK14

MAP kinase 14 , MAP kinase p38 alpha , MAPK 14 , mitogen-activated protein kinase p38 alpha , p38 mitogen activated protein kinase , CG7393-PA , p38 mitogen-activated protein kinase , p38b-PA , stress-activated p38b MAP kinase , p38 mitogen-activated kinase , cytokine suppressive anti-inflammatory drug binding protein 1 , mitogen activated protein kinase 14 , p38 MAP kinase alpha , p38 MAPK , p38 alpha , tRNA synthetase cofactor p38 , CSAIDS-binding protein 1 , mitogen-activated protein kinase 14A , stress-activated protein kinase 2a , Csaids binding protein , MAP kinase 2 , MAP kinase Mxi2 , MAX-interacting protein 2 , cytokine suppressive anti-inflammatory drug binding protein , cytokine-supressive anti-inflammatory drug binding protein , mitogen-activated protein kinase 14 , p38 MAP kinase , p38alpha Exip , reactive kinase , stress-activated protein kinase 2A , MAPK p38 , MPK2 , Mitogen-activated protein kinase 2 , mitogen-activated Mitogen-activated protein kinase 2

829797 Arabidopsis thaliana
534492 Bos taurus
403856 Canis lupus familiaris
100723285 Cavia porcellus
34780 Drosophila melanogaster
100063532 Equus caballus
421183 Gallus gallus
1432 Homo sapiens
26416 Mus musculus
100341695 Oryctolagus cuniculus
450161 Pan troglodytes
81649 Rattus norvegicus
100156630 Sus scrofa
379992 Xenopus laevis
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