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Aperçu des produits pour anti-PAK2 (PAK2) Anticorps

Full name:
anti-P21-Activated Kinase 2 Anticorps (PAK2)
Chez www.anticorps-enligne.fr sont 174 P21-Activated Kinase 2 (PAK2) Anticorps de 25 de différents fournisseurs disponibles. De plus, nous expédions PAK2 Kits (12) et PAK2 Protéines (11) et beaucoup plus de produits pour cette protéine. Un total de 210 PAK2 produits sont actuellement listés.
Synonymes:
5330420P17Rik, A130002K10Rik, AI836325, cb422, D16Ertd269e, gamma-PAK, kinase, mKIAA4182, PAK-2, pak2, Pak3, PAK65, PAKgamma, PAKI, si:dz198m22.1, wu:fb71h01, zgc:91798

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anti-Human PAK2 Anticorps:

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anti-PAK2 Anticorps mieux référencés

  1. Human Polyclonal PAK2 Primary Antibody pour EIA, IHC (p) - ABIN500439 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. dans The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 4 references for ABIN500439

  2. Human Polyclonal PAK2 Primary Antibody pour EIA, IHC (p) - ABIN500441 : Ang, Patel, Yin, Sundaram, Fritchie, Zhao, Liu, Freemerman, Wilkerson, Walter, Weissler, Shockley, Couch, Zanation, Hackman, Chera, Harris, Miller, Thorne, Hayward, Funkhouser, Olshan, Shores, Makowski, Hayes: High XRCC1 protein expression is associated with poorer survival in patients with head and neck squamous cell carcinoma. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)
    Show all 4 references for ABIN500441

  3. Human Monoclonal PAK2 Primary Antibody pour ICC, IHC - ABIN969338 : Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: A novel role for p21-activated protein kinase 2 in T cell activation. dans Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 2 references for ABIN969338

  4. Human Monoclonal PAK2 Primary Antibody pour ELISA, ICC - ABIN2869426 : Machuy, Campa, Thieck, Rudel: c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles. dans Journal of molecular biology 2007 (PubMed)
    Show all 2 references for ABIN2869426

  5. Human Polyclonal PAK2 Primary Antibody pour IHC (p), WB - ABIN318772 : Roig, Traugh: Cytostatic p21 G protein-activated protein kinase gamma-PAK. dans Vitamins and hormones 2001 (PubMed)
    Show all 2 references for ABIN318772

  6. Human Polyclonal PAK2 Primary Antibody pour IHC (p), WB - ABIN392433 : Benner, Dennis, Masaracchia: Activation of an S6/H4 kinase (PAK 65) from human placenta by intramolecular and intermolecular autophosphorylation. dans The Journal of biological chemistry 1995 (PubMed)
    Show all 2 references for ABIN392433

  7. Human Polyclonal PAK2 Primary Antibody pour EIA, IHC (p) - ABIN360318 : Martin, Bollag, McCormick, Abo: A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. dans The EMBO journal 1995 (PubMed)
    Show all 2 references for ABIN360318

  8. Human Polyclonal PAK2 Primary Antibody pour IHC, ELISA - ABIN1532071 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. dans Cell 2006 (PubMed)

  9. Human Polyclonal PAK2 Primary Antibody pour IP, WB - ABIN253074 : Qu, Misaghi, Izrael-Tomasevic, Newton, Gilmour, Lamkanfi, Louie, Kayagaki, Liu, Kömüves, Cupp, Arnott, Monack, Dixit: Phosphorylation of NLRC4 is critical for inflammasome activation. dans Nature 2012 (PubMed)

Plus d’anticorps contre PAK2 partenaires d’interaction

Zebrafish P21-Activated Kinase 2 (PAK2) interaction partners

  1. EphrinB ligands B2a and B3b, the Ephb4a (Montrer EPHB4 Anticorps) receptor and the Pak2a kinase are required for the development of pharyngeal pouches and the segmentation of the posterior facial skeleton.

  2. Essential in vivo role for betaPix (Montrer ARHGEF7 Anticorps) and Pak2a during embryonic development and a previously unrecognized pathway specifically involved in cerebrovascular stabilization. [BetaPix (Montrer ARHGEF7 Anticorps) AND Pak2a]

  3. Data provide evidence for a critical function of Pak2 in vascular integrity and demonstrate a severe disease phenotype resulting from loss of Pak2 function.

Human P21-Activated Kinase 2 (PAK2) interaction partners

  1. We found that overexpression of miR (Montrer MLXIP Anticorps)-137 inhibited the proliferation of melanoma cells, which could be phenocopied by knockdown of PAK2 using siRNAs.

  2. PAK2 is a direct effector of TSC1 (Montrer TSC1 Anticorps)-TSC2 (Montrer TSC2 Anticorps)-RHEB (Montrer RHEB Anticorps) signaling and a new target for rational drug therapy in TSC (Montrer SLC12A3 Anticorps).

  3. Nef exploits PAK2 in a stepwise mechanism in which its kinase activity cooperates with an adaptor function for the exocyst complex to inhibit host cell actin dynamics.

  4. Cytoplasmic Pak2 may promote cell proliferation in normal endometrium during menstrual cycle.

  5. Further analyses show that HDAC6 (Montrer HDAC6 Anticorps) may promote growth of GBM cells through inhibition of SMAD2 (Montrer SMAD2 Anticorps) phosphorylation to downregulate p21 (Montrer CDKN1A Anticorps)

  6. Pak1 (Montrer PAK1 Anticorps) and Pak2 counteract centrosome separation in a kinase-dependent manner.

  7. Findings indicate that repression of microRNA miR (Montrer MLXIP Anticorps)-134 and consequent up-regulation of p21-activated kinase 2 (Pak2) might contribute to paclitaxel resistance.

  8. Inhibition of PAK activation at late G2-phase centrosomes caused by Rac1 inactivation coincides with impeded activation of Aurora A (Montrer AURKA Anticorps) and the CyclinB (Montrer CCNB1 Anticorps)/Cdk1 (Montrer CDK1 Anticorps) complex and delayed mitotic entry.

  9. Data show that group I p21 (Montrer CDKN1A Anticorps)-activated kinases (Paks) Pak1 (Montrer PAK1 Anticorps) and Pak2 were much more abundant than Pak3 in meningioma.

  10. Results identified Pak2 as a possibly important mediator of ovarian cancer cell migration on extracellular matrix.

Mouse (Murine) P21-Activated Kinase 2 (PAK2) interaction partners

  1. Mechanistic insights into the role of Pak2 in hematopoietic stem cells migration and homing.

  2. Pak2 disruption decreased the survival and proliferation of multicytokine stimulated immature progenitors.

  3. The data suggest that Pak2 controls thymic Natural Killer T-cell development by providing a signal that links Egr2 (Montrer EGR2 Anticorps) to induce PLZF (Montrer ZBTB16 Anticorps), in part by regulating signaling lymphocyte activation molecule (Montrer SLAMF1 Anticorps) 6 expression.

  4. In adult endothelial cells, Pak2 depletion leads to severe apoptosis and acute angiogenesis defects, and in adult mice, endothelial Pak2 deletion leads to increased vascular permeability.

  5. Pak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral Tolerance

  6. Failure to induce proper actin cytoskeletal remodeling impaired PLCgamma1 and Erk1/2 signaling in the absence of Pak2, uncovering the critical function of Pak2 as an essential regulator that governs the actin cytoskeleton-dependent signaling

  7. thrombin (Montrer F2 Anticorps) induces monocyte/macrophage migration via PAR1 (Montrer F2R Anticorps)-Galpha12 (Montrer GNA12 Anticorps)-dependent Pyk2 (Montrer PTK2B Anticorps)-mediated Gab1 (Montrer GAB1 Anticorps) and p115 RhoGEF (Montrer ARHGEF1 Anticorps) interactions, leading to Rac1- and RhoA (Montrer RHOA Anticorps)-targeted Pak2 activation.

  8. p21 (Montrer D4S234E Anticorps)-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

  9. Pak2, but not Pak1 (Montrer PAK1 Anticorps), negatively regulates RhoA (Montrer RHOA Anticorps) via phosphorylation of the guanine nucleotide exchange factor (Montrer ARHGEF12 Anticorps) GEF-H1 (Montrer ARHGEF2 Anticorps) at an inhibitory site, leading to increased GEF-H1 (Montrer ARHGEF2 Anticorps) microtubule binding and loss of RhoA (Montrer RHOA Anticorps) stimulation

  10. Full-length PAK-2 rather than the caspase-activated PAK-2p34 is required for normal embryonic development.

Cow (Bovine) P21-Activated Kinase 2 (PAK2) interaction partners

  1. Basement membrane proteins promote PAK2 Ser (Montrer SIGLEC1 Anticorps)-20 phosphorylation through enhanced eNOS (Montrer NOS3 Anticorps) activation and NO production.

PAK2 profil antigène

Antigen Summary

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Alternative names and synonyms associated with PAK2

  • p21 (CDKN1A)-activated kinase 2a (pak2a) anticorps
  • p21 protein (Cdc42/Rac)-activated kinase 2 (pak2) anticorps
  • p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2) anticorps
  • p21 protein (Cdc42/Rac)-activated kinase 2 (Pak2) anticorps
  • 5330420P17Rik anticorps
  • A130002K10Rik anticorps
  • AI836325 anticorps
  • cb422 anticorps
  • D16Ertd269e anticorps
  • gamma-PAK anticorps
  • kinase anticorps
  • mKIAA4182 anticorps
  • PAK-2 anticorps
  • pak2 anticorps
  • Pak3 anticorps
  • PAK65 anticorps
  • PAKgamma anticorps
  • PAKI anticorps
  • si:dz198m22.1 anticorps
  • wu:fb71h01 anticorps
  • zgc:91798 anticorps

Protein level used designations for PAK2

p21 (CDKN1A)-activated kinase 2 , p21-activated kinase 2 , redhead , rhd , serine/threonine-protein kinase PAK 2 , p21 activated kinase 2 , PAK-2 , S6/H4 kinase , gamma-PAK , p58 , p21-activated kinase I , p21-activated protein kinase I

GENE ID SPECIES
266749 Danio rerio
399090 Xenopus laevis
460965 Pan troglodytes
5062 Homo sapiens
224105 Mus musculus
29432 Rattus norvegicus
513673 Bos taurus
612814 Canis lupus familiaris
424860 Gallus gallus
100009535 Oryctolagus cuniculus
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