Aperçu des produits pour PPP1R13B (PPP1R13B) Kits ELISA

Full name:
Protein Phosphatase 1, Regulatory Subunit 13B Kits ELISA (PPP1R13B)
Chez www.anticorps-enligne.fr sont 2 Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Kits ELISA de 1 de différents fournisseurs disponibles. De plus, nous expédions PPP1R13B Anticorps (60) et PPP1R13B Protéines (4) et beaucoup plus de produits pour cette protéine. Un total de 72 PPP1R13B produits sont actuellement listés.
Synonymes:
AI449786, ASPP1, AW545810, p53BP2-like, p85, pp2ca1, ppp1r13b, si:ch211-253p18.1, Tp53bp2, Trp53bp2, wu:fd42g12, zgc:153820
list all ELISA KIts Gène GeneID UniProt
PPP1R13B 21981 Q62415
PPP1R13B 23368 Q96KQ4
Rat PPP1R13B PPP1R13B 314465  

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PPP1R13B (PPP1R13B) Kits ELISA par réactivité

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Plus Kits ELISA pour PPP1R13B partenaires d'interaction

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) interaction partners

  1. After genotoxic stress, Aspp1 promotes hematopoietic stem cell (HSC (Montrer FUT1 Kits ELISA)) cycling and induces p53 (Montrer TP53 Kits ELISA)-dependent apoptosis in cells with persistent DNA damage foci. Aspp1 also attenuates HSC (Montrer FUT1 Kits ELISA) self-renewal and accumulation of DNA damage in p53 (Montrer TP53 Kits ELISA) null HSCs.

  2. Our study demonstrates a novel role for ASPP1 and ASPP2 (Montrer TP53BP2 Kits ELISA) in the death of retinal ganglion cells.

  3. Aspp1 plays a crucial role in the initial assembly and function of lymphatic vessels during mouse development in a p53 (Montrer TP53 Kits ELISA)-independent manner.

Human Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) interaction partners

  1. Increased expression of p53 (Montrer TP53 Kits ELISA) and ASPP1 and downregulation of iASPP (Montrer PPP1R13L Kits ELISA).

  2. ASPP1/2-PP1 (Montrer PPA1 Kits ELISA) complexes are required for chromosome segregation and kinetochore-microtubule attachments.

  3. ASPP1/2 interacted with centrosome linker protein (Montrer LAT Kits ELISA) C (Montrer PROC Kits ELISA)-Nap1 (Montrer CEP250 Kits ELISA). Co-depletion of ASPP1 and ASPP2 (Montrer TP53BP2 Kits ELISA) inhibited re-association of C-Nap1 (Montrer CEP250 Kits ELISA) with centrosome at the end of mitosis.

  4. ASPP1 and ASPP2 (Montrer TP53BP2 Kits ELISA) cooperate with oncogenic RAS to enhance the transcription and apoptotic function of p53 (Montrer TP53 Kits ELISA).

  5. When the Px(T)PxR (Montrer NR1I2 Kits ELISA) motif is deleted or mutated via insertion of a phosphorylation site mimic (T311D), PP-1c fails to bind to all three ASPP proteins, ASPP1, ASPP2 (Montrer TP53BP2 Kits ELISA) and iASPP (Montrer PPP1R13L Kits ELISA).

  6. the mRNA expression of ASPP1 and ASPP2 (Montrer TP53BP2 Kits ELISA) was frequently dowregulated in tumor tissues, and this decreased significantly in samples expressing wild-type p53 (Montrer TP53 Kits ELISA)

  7. ASPP1 promoter methylation may be associated with the malignant progression of non-small cell lung cancer, and ASPP1 expression promotes cellular apoptosis.

  8. The ability of ASPP1 to activate YAP (Montrer YAP1 Kits ELISA) results in the decreased expression of LATS2, which lowers the ability of p53 (Montrer TP53 Kits ELISA) to induce p21 (Montrer CDKN1A Kits ELISA), cell-cycle arrest and senescence.

  9. overexpression of ASPP1 rendered MCF-7 and MDA-MB231 breast cancer cells more sensitive to resveratrol-mediated apoptosis via the E2F (Montrer E2F1 Kits ELISA) pathway

  10. Suggest that downregulation of ASPP1 by hypermethylation may be involved in the pathogenesis and progress of gestational trophoblastic disease, probably through its effect on apoptosis.

PPP1R13B profil antigène

Antigen Summary

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Alternative names and synonyms associated with PPP1R13B

  • protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab) Elisa Kit
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (PPP1R13B) Elisa Kit
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (ppp1r13b) Elisa Kit
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b) Elisa Kit
  • protein phosphatase 1, regulatory (inhibitor) subunit 13Bb (ppp1r13bb) Elisa Kit
  • protein phosphatase 1, regulatory subunit 13B (PPP1R13B) Elisa Kit
  • protein phosphatase 1, regulatory subunit 13B (ppp1r13b) Elisa Kit
  • protein phosphatase 1, regulatory subunit 13B (Ppp1r13b) Elisa Kit
  • AI449786 Elisa Kit
  • ASPP1 Elisa Kit
  • AW545810 Elisa Kit
  • p53BP2-like Elisa Kit
  • p85 Elisa Kit
  • pp2ca1 Elisa Kit
  • ppp1r13b Elisa Kit
  • si:ch211-253p18.1 Elisa Kit
  • Tp53bp2 Elisa Kit
  • Trp53bp2 Elisa Kit
  • wu:fd42g12 Elisa Kit
  • zgc:153820 Elisa Kit

Protein level used designations for PPP1R13B

protein phosphatase type 2C alpha 1 , protein phosphatase 1, regulatory (inhibitor) subunit 13B , apoptosis-stimulating protein of p53, 1 , apoptosis-stimulating of p53 protein 1-like , apoptosis-stimulating of p53 protein 1 , protein phosphatase 1 regulatory subunit 13B , transformation related protein 53 binding protein 2 , tumor protein p53 binding protein, 2 , tumor protein p53-binding protein, 2 , apoptosis-stimulating protein of p53

GENE ID SPECIES
30703 Danio rerio
423487 Gallus gallus
453193 Pan troglodytes
490874 Canis lupus familiaris
700432 Macaca mulatta
100020778 Monodelphis domestica
100060064 Equus caballus
100357525 Oryctolagus cuniculus
100380068 Xenopus (Silurana) tropicalis
100395359 Callithrix jacchus
100438788 Pongo abelii
100481667 Ailuropoda melanoleuca
100539199 Meleagris gallopavo
21981 Mus musculus
557278 Danio rerio
23368 Homo sapiens
496341 Xenopus laevis
511414 Bos taurus
314465 Rattus norvegicus
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