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Aperçu des produits pour anti-TICAM2 (TICAM2) Anticorps

Full name:
anti-Toll-Like Receptor Adaptor Molecule 2 Anticorps (TICAM2)
Chez sont 112 Toll-Like Receptor Adaptor Molecule 2 (TICAM2) Anticorps de 24 de différents fournisseurs disponibles. De plus, nous expédions TICAM2 Protéines (12) et beaucoup plus de produits pour cette protéine. Un total de 138 TICAM2 produits sont actuellement listés.
B430113A10, MyD88-4, TICAM-2, TIRAP3, Tirp, TRAM, Trif
afficher tous les anticorps Gène GeneID UniProt
TICAM2 364867  
TICAM2 353376 Q86XR7
TICAM2 225471 Q8BJQ4

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Réactivités les plus populaires pour anti-TICAM2 (TICAM2) Anticorps

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anti-Rat (Rattus) TICAM2 Anticorps:

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anti-Mouse (Murine) TICAM2 Anticorps:

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anti-TICAM2 Anticorps mieux référencés

  1. Human Monoclonal TICAM2 Primary Antibody pour FACS - ABIN2665412 : Enokizono, Kumeta, Funami, Horiuchi, Sarmiento, Yamashita, Standley, Matsumoto, Seya, Inagaki: Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling. dans Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)
    Show all 6 references for ABIN2665412

  2. Human Polyclonal TICAM2 Primary Antibody pour EIA, IF - ABIN500929 : ONeill, Fitzgerald, Bowie: The Toll-IL-1 receptor adaptor family grows to five members. dans Trends in immunology 2003 (PubMed)
    Show all 4 references for ABIN500929

  3. Human Polyclonal TICAM2 Primary Antibody pour DB, EIA - ABIN493396 : Oshiumi, Sasai, Shida, Fujita, Matsumoto, Seya: TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN493396

  4. Human Polyclonal TICAM2 Primary Antibody pour DB, EIA - ABIN493528 : Oshiumi, Matsumoto, Funami, Akazawa, Seya: TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. dans Nature immunology 2003 (PubMed)
    Show all 3 references for ABIN493528

  5. Human Polyclonal TICAM2 Primary Antibody pour IHC (fro), WB - ABIN265137 : Vogel, Fitzgerald, Fenton: TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. dans Molecular interventions 2004 (PubMed)
    Show all 2 references for ABIN265137

  6. Human Polyclonal TICAM2 Primary Antibody pour WB - ABIN657981 : Lysakova-Devine, Keogh, Harrington, Nagpal, Halle, Golenbock, Monie, Bowie: Viral inhibitory peptide of TLR4, a peptide derived from vaccinia protein A46, specifically inhibits TLR4 by directly targeting MyD88 adaptor-like and TRIF-related adaptor molecule. dans Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)

Plus d’anticorps contre TICAM2 partenaires d’interaction

Human Toll-Like Receptor Adaptor Molecule 2 (TICAM2) interaction partners

  1. Data show that Toll (Montrer TLR4 Anticorps)/IL-1R domain-containing adaptor molecule (TICAM)-2 possesses two conserved acidic amino acids, D91 and E92, which regulate TICAM-2 self-activation and signaling.

  2. Findings were SNPs in TICAM2 (P = 3.6 x 10(-6)) and IL1B (Montrer IL1B Anticorps) (P = 4.3 x 10(-5)) associated with TB.

  3. TRAM (Montrer TRAM1 Anticorps) plays a role in TLR7 (Montrer TLR7 Anticorps) signaling through a novel signaling axis towards the activation of anti-viral immunity.

  4. TRAM (Montrer TRAM1 Anticorps) acts as a sorting adaptor not only for TLR4 (Montrer TLR4 Anticorps), but also for TLR2 (Montrer TLR2 Anticorps), to facilitate signaling to IRF7 (Montrer IRF7 Anticorps) at the endosome, which explains how TLR2 (Montrer TLR2 Anticorps) is capable of causing type I IFN induction.

  5. A putative TRAF6 (Montrer TRAF6 Anticorps)-binding motif in TRAM (Montrer TRAM1 Anticorps) may mediate a new TRAM (Montrer TRAM1 Anticorps) function in TLR4 (Montrer TLR4 Anticorps) signaling in regulating inflammatory responses, distinct from its bridging TLR4 (Montrer TLR4 Anticorps) and TRIF (Montrer TRIM69 Anticorps). A TRAM (Montrer TRAM1 Anticorps) E183A mutation abolished this.

  6. results suggest TLR adaptor molecules knockdown, such as MyD88 (Montrer MYD88 Anticorps) or TRAM (Montrer TRAM1 Anticorps), can decrease IL-6 (Montrer IL6 Anticorps) and IL-8 (Montrer IL8 Anticorps) mRNA and increase CXCL12 (Montrer CXCL12 Anticorps) mRNA expression in HGF (Montrer HGF Anticorps) and HPDLF.

  7. The homotypic interaction between TICAM-2 TIR is indispensable to present a scaffold for recruiting the monomeric moiety of the TICAM-1 (Montrer TICAM1 Anticorps) TIR dimer.

  8. induction of both IL-6 (Montrer IL6 Anticorps) and IL-8 (Montrer IL8 Anticorps) is associated with elevated TIRAP (Montrer TIRAP Anticorps) and reduced TRAM (Montrer TRAM1 Anticorps) mRNA expression

  9. Data indicate that MyD88 (Montrer MYD88 Anticorps) works together with the IL-1 (Montrer IL1A Anticorps)/IL-18 (Montrer IL18 Anticorps) receptors, can interact with two distinct sorting adaptors, TRAM (Montrer TRAM1 Anticorps) and Mal (Montrer MAL Anticorps), in a conserved manner.

  10. viral inhibitor peptide of TLR4 (Montrer TLR4 Anticorps) possibly represents a surface domain of A46 that specifically inhibits TLR4 (Montrer TLR4 Anticorps) by masking critical binding sites on MyD88 adaptor (Montrer MYD88 Anticorps)-like and TRIF-related adaptor molecule

Mouse (Murine) Toll-Like Receptor Adaptor Molecule 2 (TICAM2) interaction partners

  1. TRIF (Montrer RNF138 Anticorps)-independent pathways can be involved in the downregulation of drug metabolizing enzymes and transporters through TLR4 (Montrer TLR4 Anticorps) and 3. JNK (Montrer MAPK8 Anticorps)-dependent mechanisms likely mediate this downregulation.

  2. Data show that annexin A2 (AnxA2 (Montrer ANXA2 Anticorps)) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4 (Montrer TLR4 Anticorps))-initiated TRAM protein (Montrer TRAM2 Anticorps)-TRIF (Montrer RNF138 Anticorps) protein pathway occurring on endosomes.

  3. TRIF (Montrer RNF138 Anticorps) mediates antibacterial defense during Gram-negative pneumonia, at least in part, by inducing IFN-x03B3; at the primary site of infection.

  4. The authors confirmed that the protective effect of poly I:C against enteric infection of mice with Yersinia enterocolitica was dependent on TLR3 (Montrer TLR3 Anticorps)-mediated TRIF (Montrer RNF138 Anticorps) signaling by using TLR3 (Montrer TLR3 Anticorps)-deficient mice.

  5. MMP-12 (Montrer MMP12 Anticorps) up-regulation mediated by SARM (Montrer SARM1 Anticorps)-TRIF (Montrer RNF138 Anticorps) signaling pathway contributes to IFN-gamma (Montrer IFNG Anticorps)-independent airway inflammation and AHR (Montrer AHR Anticorps) post RSV infection in nude mice.

  6. HMGB1 (Montrer HMGB1 Anticorps) and its downstream TLR4 (Montrer TLR4 Anticorps)/Myd88 (Montrer MYD88 Anticorps)/TRIF (Montrer RNF138 Anticorps) signaling pathway play important roles in the mouse intestinal I/R injury.

  7. TLR4 (Montrer TLR4 Anticorps), TRIF (Montrer RNF138 Anticorps), and MyD88 (Montrer MYD88 Anticorps) mediate the intraocular inflammatory response in endophthalmitis caused by Bacillus cereus.

  8. TRIF (Montrer RNF138 Anticorps) is a mediator of the innate and adaptive immune interactions in the protective properties of memory immunity against Gram-negative bacteria.

  9. Inhibitory effects of SP were mediated through the regulation of TRIF (Montrer RNF138 Anticorps)-dependent signaling.

  10. These findings indicate that a balanced immune response operating through both TRIF (Montrer RNF138 Anticorps)-driven and MyD88 (Montrer MYD88 Anticorps)-driven pathways likely provides the most effective host cell intrinsic antiviral defense responses to severe SARS (Montrer SARS Anticorps)-CoV disease

TICAM2 profil antigène

Antigen Summary

TIRP is a Toll/interleukin-1 receptor (IL1R\; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4\; MIM 603030).

Alternative names and synonyms associated with TICAM2

  • toll-like receptor adaptor molecule 2 (Ticam2) anticorps
  • toll-like receptor adaptor molecule 2 (TICAM2) anticorps
  • B430113A10 anticorps
  • MyD88-4 anticorps
  • TICAM-2 anticorps
  • TIRAP3 anticorps
  • Tirp anticorps
  • TRAM anticorps
  • Trif anticorps

Protein level used designations for TICAM2

TIR domain-containing adapter molecule 2 , TMED7-TICAM2 readthrough , NF-kappa-B-activating protein 502 , TRIF-related adaptor molecule , cytoplasmic adaptor , putative NF-kappa-B-activating protein 502 , toll-like receptor adaptor protein 3 , toll/interleukin-1 receptor (TIR) domain-containing adapter protein , TIR domain-containing adapter protein , TRIF-related adapter molecule TRAM , Toll-interleukin I receptor domain (TIR)-containing adaptor molecule (TICAM) 2 , toll/interleukin-1 receptor domain-containing protein , TRIF-related adapter molecule

364867 Rattus norvegicus
100029323 Monodelphis domestica
100409449 Callithrix jacchus
100500706 Pan troglodytes
100520421 Sus scrofa
100529854 Equus caballus
100533188 Canis lupus familiaris
353376 Homo sapiens
225471 Mus musculus
539350 Bos taurus
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